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Dynamic Nanobiosensor Platform for Viral and Tumor Nucleic Acid Detection
TS-052072 — A rapid, nucleic acid-based, point-of-care diagnostic.
The current gold-standard molecular diagnostic assay, quantitative reverse transcriptase (RT)-PCR, although accurate, is labor intensive (5-step workflow) and time consuming. Due to centralized laboratory testing, the time to results for RT-PCR can vary from 1 day up to 2 weeks, depending on the s…
  • College: College of Engineering (COE)
  • Inventors: Halley, Patrick; Castro, Carlos; Lucas, Christopher; Marras, Alexander; Shahhosseini, Melika
  • Licensing Officer: Ezzell, Janel

Novel Ergonomic Scalpel Handle
TS-051663 — Alleviate and prevent occupational stresses using this novel scalpel design.
A highly unfortunate outcome of the 2020 coronavirus pandemic is the over 200,000 American deaths that have unexpectedly overloaded medical autopsy services across the United States. With this heightened need for autopsy services previously unseen occupational hazards relating to repetitive motion…
  • College: College of Medicine (COM)
  • Inventors: Sachire, Jennifer
  • Licensing Officer: Ezzell, Janel

Finding rare events by knowing where NOT to look
TS-051417 — Traditional regression analysis has been a staple in predicting cause-effect relationships. Counltess industries use these methods to predict rare events, from economic issues to cancer research, causality is often a desired result. Given the vast amount of potential variables it sometimes becomes…
  • College: College of Arts & Sciences
  • Inventors: Melamed, David; Schoon, Eric
  • Licensing Officer: Hong, Dongsung

Activation of human Argonaute3 (AGO3) using cityRNAs
TS-051298 — MicroRNAs (miRNAs) are small non-coding RNAs that control gene expression post-transcriptionally. Their sequences differ, but their lengths fall within a range of ~20-23 nucleotides because the precursor miRNAs are processed by Dicer. Dicer cleaves long double-stranded RNA (dsRNA) molecules into s…
  • College: College of Arts & Sciences
  • Inventors: Nakanishi, Kotaro; Park, Mi Seul
  • Licensing Officer: Ezzell, Janel

Modular Dc Circuit Breaker with Integrated Energy Storage for Future Dc Networks
TS-051200 — Traditional AC distribution is not suitable for a wide range of applications in regard to efficiency, cost, and power carrying capacity compared to alternative distributions. Low voltage distribution suffers from high transmission losses due to higher current requirements necessitating thicker, he…
  • College: College of Engineering (COE)
  • Inventors: Wang, Jin; Na, Risha; Zhang, Yue
  • Licensing Officer: Hong, Dongsung

Development of a live attenuated vaccine for leishmaniasis using CRISPR technology
TS-051167 — Methods of production and use of modified Leishmania species and compositions of live, attenuated organisms, immunogenic compositions, vaccines, and pharmaceutical compositions.
Leishmaniasis is a neglected tropical disease caused by infection with protozoans of the 15 genus Leishmania that is transmitted by infected sand flies. Worldwide, an estimated 1 billion people are at risk of infection in tropical and subtropical countries, with up to 1.7 million new cases in 98 c…
  • College: College of Medicine (COM)
  • Inventors: Satoskar, Abhay
  • Licensing Officer: Davis, Stewart

Wireless Identification of Viral Infection (WiVi)
TS-051091 — This invention introduces a novel method for airborne viral pandemic mitigation using WiFi access points as infrastructural spatiotemporal anchors.
New viruses are constantly being discovered. From SARS to Bird Flu, and HIV to COVID-19. The threat of global pandemics is real and methods for tracing and controlling it need to be available. It is necessary that there are capabilities available which can inform the modeling of future viral spre…
  • College: College of Engineering (COE)
  • Inventors: El Gamal, Hesham
  • Licensing Officer: Hong, Dongsung

Concept Discovery from Text via Knowledge Transfer
TS-050856 — A better way for systems to organize, file, or index documents or content based on actual or anticipated information needed in the form of a user query or natural language question.
Data Processing and (IT)-related activities, ranging from web hosting to automated data entry services are more important than ever due to the large amounts of data collected through technology. According to IBIS World, "Companies will increasingly capture more data, requiring the outside exp…
  • College: College of Engineering (COE)
  • Inventors: Das, Manirupa; Fosler-Lussier, John Eric; Ramnath, Rajiv
  • Licensing Officer: Hong, Dongsung

Ultra-high-throughput sequencing approach enabling whole-community COVID-19 screening
TS-050647 — REMBRANDT: a high-throughput Next Generation Sequencing-based approach for the simultaneous screening of over 100,000 COVID-19 samples per day.
The SARS-CoV-2 virus, which causes COVID-19 syndrome, has rapidly spread throughout the world and was recently classified by the WHO as a pandemic pathogen. Severe disease that requires hospital admission occurs in 20% of cases, and a subset of these patients require ICU care; the death rate from …
  • College: College of Medicine (COM)
  • Inventors: Palmieri, Dario; Fishel, Richard; Miles, Wayne; Siddiqui, Jalal "Jalal"
  • Licensing Officer: Ezzell, Janel

Method of forming low turn on and high breakdown voltage lateral diode.
TS-050626 — A hybrid Schottky and metal/high K dielectric/semiconductor contact to realize higher breakdown and low turn-on voltage for lateral diode based on wide bandgap semiconductors.
Practical realization of high breakdown fields in wide bandgap semiconductors such as GaN, SiC, typically requires the use of p-n junction, which require a turn-on voltage comparable to the bandgap of these semiconductors. For lower voltage applications, the forward or ON-state power loss due to h…
  • College: College of Engineering (COE)
  • Inventors: Rahman, Mohammad Wahidur "Wahidur"; Rajan, Siddharth
  • Licensing Officer: Hong, Dongsung

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