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Methods for Making Three Dimensional Microfluidic Bioreactor Array
TS-037642 — Design for a three-dimensional microfluidic bioreactor array; device allows for culturing of a variety of cell types without contamination.
Cell culture in a three-dimensional fluidic-flow microenvironment is critical for long-term cell-based assays. Conducting in vitro research offers an accessible, reproducible, and reliable mode of investigation for therapeutic decisions before work is conducted in vivo. However, because of the com…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Wen, Yuan
  • Licensing Officer: Paschall, Christopher

Novel Use of Fostamatinib as a Therapeutic for Liver Cancer, both as First-Line Therapy and Following Acquired Resistance to Sorafenib
TS-032418 — A combination-therapy that has the potential to overcome and/or prevent the commonly observed acquisition of sorafenib resistance, which is associated with treatment failure in patients with hepatocellular carcinoma.
Hepatocellular carcinoma (HCC) kills nearly all patients within a year of diagnosis, and results in between 250,000 and one million deaths globally per year. In the US, incidences of HCC have nearly tripled in the past 30 years and currently remain one of the fastest growing causes of cancer-relat…
  • College: College of Medicine (COM)
  • Inventors: Motiwala, Tasneem; Regan, Kelly; Reyes, Ryan
  • Licensing Officer: Flammang, Ann Marie
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