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Antibiotic-free selection of plasmids for recombinant DNA technology applications
TS-065461 — The Need: In the field of modern biochemistry, the production of recombinant proteins in bacterial hosts like Escherichia coli is integral for both research and industrial applications. However, the traditional method of using antibiotics for selection in protein production is costly and contributes…
  • College: College of Arts & Sciences
  • Inventors: Gopalan, Venkat
  • Licensing Officer: Willson, Christopher

Precision RNA-PROTACs: Revolutionizing Therapeutic Targeting of Dysregulated Ribonucleoprotein Complexes
TS-065457 — The Need: In the realm of therapeutic development, there's a pressing need for precise targeting of dysregulated ribonucleoprotein (RNP) complexes to combat various diseases, particularly neurodegenerative disorders like ALS, Alzheimer’s, and Huntington’s diseases. Traditional metho…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"; Strong, Rebekah
  • Licensing Officer: Willson, Christopher

Revolutionizing RNA-Protein Interaction Mapping: Precision Proximity Labeling Technology
TS-065456 — The Need In modern biological research, there is a pressing demand for technologies that enable precise mapping of RNA-protein interactions within Ribonucleoprotein (RNP) complexes. Traditional methods often lack the capability to pinpoint these interactions at the level of secondary structure moti…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"
  • Licensing Officer: Willson, Christopher

Advancing RNA Detection with Innovative Peptide-Based Fluorescent Probes
TS-065455 — The Need: In modern biotechnology and biomedical research, there is an escalating demand for efficient tools that can accurately detect and analyze specific RNA sequences. The ability to precisely target and identify RNA molecules, particularly U-rich sequences, is crucial for various applications s…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; DeSantis, Christopher; Gopalan, Venkat; Liang, Yufeng; Mao, Jie; Marathe, Ila; Miao, Shiqin "Shiqin"
  • Licensing Officer: Willson, Christopher

Monoclonal Antibodies for Soybean Rust Diagnostic Assay
TS-065454 — The Need: As agriculture faces increasing challenges from plant pathogens, rapid and accurate detection methods are crucial to safeguarding crop yields and ensuring food security. Traditional methods of pathogen detection often suffer from delays in diagnosis, leading to significant crop damage and …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Dorrance, Anne; Luster, Douglas; McMahon, Michael; Miller, Sally
  • Licensing Officer: Dahlman, Jason "Jay"

Revolutionizing Pharmaceutical Synthesis: Advancements in Metal-Catalyzed Coupling Technology
TS-064824 — The Need In the pharmaceutical industry, the synthesis of complex organic substrates is crucial for the development of life-saving medications. However, traditional metal-catalyzed coupling reactions often face significant challenges when applied to these complex substrates, leading to high failure…
  • College: College of Arts & Sciences
  • Inventors: Sevov, Christo; Dinh, Long; Hamby, Taylor; Starbuck, Hunter
  • Licensing Officer: Willson, Christopher

COLMARppm: web-server tool for prediction of NMR chemical shifts
TS-064585 — COLMARppm offers a swift and accurate solution to the longstanding challenges in metabolomics research. Unique features and capabilities position it as a crucial tool for researchers seeking to unlock unknown metabolites, contributing to health research The Need In the field of metabolomics resear…
  • College: College of Arts & Sciences
  • Inventors: Bruschweiler, Rafael; Li, Dawei "Dawei"; Rigel, Nick
  • Licensing Officer: Willson, Christopher

Magnetic Nanoparticles for Cancer Cell Classification
TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year. The Need Developing drugs for cance…
  • College: College of Arts & Sciences
  • Inventors: Schultz, Zachary; Rist, David; Skardal, Aleksander; Venere, Monica
  • Licensing Officer: Willson, Christopher

Co-Axial Contained Electrospray Ionization Platform for Mass Spec.
TS-064299 — Mass spectrometry (MS) is used across a wide range of applications involving analytical chemistry. Various MS techniques, often coupled with liquid chromatography (LC), allow for detection of various chemical analytes, from drug metabolites, pesticides, food adulterants, and natural product extracts…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Burris, Benjamin "Ben"; Grooms, Alex; Heiss, Derik; Kulyk, Dmytro
  • Licensing Officer: Willson, Christopher

Drosophila melanogaster muscle stem cell line
TS-064271 — The Need In the rapidly advancing landscape of life sciences, researchers and biotech companies face an escalating demand for reliable and versatile cell lines. The need for a specialized cell line that combines adaptability, reproducibility, and ease of use is paramount in accelerating breakthroug…
  • College: College of Arts & Sciences
  • Inventors: Simcox, Amanda
  • Licensing Officer: Dahlman, Jason "Jay"

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