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3D Object-based Segmentation-based Quantification of Spatial Protein Organization (OBS3D)
TS-066233 — Protein analysis is foundational to understanding human physiology and is helpful for basic research, diagnosis, guiding treatment, and monitoring of human disease. There are several widely used platforms for evaluating protein function. The primary tools used in protein analysis on cells and tissues include antibody/aptamer, fluorescent detection systems, and mass spectrometry.
Colocalization analysis is the current standard technique for assessing spatial association of co‐labeled proteins in cells using multicolor immunofluorescence images. However, these tools are limited because multiple antigens nearby exhibit overlapping staining, which leads to inaccurate analys…
  • College: College of Engineering (COE)
  • Inventors: Veeraraghavan, Rengasayee
  • Licensing Officer: Zinn, Ryan

Streamline Your Building Design Workflow with AutoCAD to Revit Conversion Technology
TS-065818 — The Need In the architecture, engineering, and construction (AEC) industry, the need for seamless and efficient conversion of AutoCAD drawings to Revit models is paramount. As projects grow in complexity and scale, the ability to transition seamlessly between these platforms becomes essential for m…
  • College: Senior VP Admin & Planning
  • Inventors: Porostosky, Joseph; Palmer, Tracy; Pifher, David
  • Licensing Officer: Dahlman, Jason "Jay"

Systems and Methods of Reminding Drivers of the Stalking Vehicles on the Road
TS-063308 — In today’s world, privacy and safety are paramount. Being followed by other vehicles during driving can be unnerving and potentially dangerous, leading to privacy leakage and even significant traffic accidents. There is a pressing need for a solution that can detect abnormal following vehicl…
  • College: College of Engineering (COE)
  • Inventors: Sun, Wei; Srinivasan, Kannan
  • Licensing Officer: Randhawa, Davinder

A Regularized Conditional GAN for Posterior Sampling in Inverse Problems
TS-063238 — A novel regularization technique applicable for medical imaging applications that leverages conditional generative adversarial networks (cGANs) to generate reconstructed images in significantly shorter timeframes. The Need Several techniques are used for image reconstruction in the medical aren…
  • College: College of Engineering (COE)
  • Inventors: Bendel, Matthew; Ahmad, Rizwan; Schniter, Philip
  • Licensing Officer: Hampton, Andrew

Network-based Approach for Accurate Brain Modeling
TS-062628 — More than a billion people worldwide suffer from some neurological disorders, such as Alzheimer's, Parkinson's, multiple sclerosis, epilepsy, stroke, autism, addiction, and many others. These conditions result in more than 7 million deaths, with associated costs exceeding $1.5 trillion annua…
  • College: College of Arts & Sciences
  • Inventors: Cranmer, Skyler; Bhamidi, Shankar; Denny, Mathew; Desmarais, Bruce; Lu, Zhong-Lin; Stillman, Paul; Wilson, James
  • Licensing Officer: Dahlman, Jason "Jay"

NMR Spectra Analysis of NMR Software
TS-062576 — Nuclear Magnetic Resonance (NMR) allows the molecular structure of a material to be analyzed by observing and measuring the interaction of nuclear spins via a powerful magnetic field. NMR can be used to determine molecular conformation in solution and physical properties at the molecular level such …
  • College: Enterprise for Research, Innovation and Knowledge (ERIK)
  • Inventors: Li, Da-Wei; Bruschweiler, Rafael
  • Licensing Officer: Dahlman, Jason "Jay"

NMR Spectra Analysis of NMR Software
TS-062574 — Nuclear Magnetic Resonance (NMR) allows the molecular structure of a material to be analyzed by observing and measuring the interaction of nuclear spins via a powerful magnetic field. NMR can be used to determine molecular conformation in solution and physical properties at the molecular level such …
  • College: College of Arts & Sciences
  • Inventors: Li, Dawei "Dawei"; Bruschweiler, Rafael
  • Licensing Officer: Dahlman, Jason "Jay"

A novel computational procedure for accelerated, calibrationless magnetic resonance image reconstruction (Free-breathing Accelerated MRI Portfolio)
TS-062487 — Magnetic Resonance Imaging (MRI) is a versatile noninvasive imaging tool that is routinely used to evaluate many diseases and conditions. MRI offers exquisite soft tissue contrast and high spatial resolution to enable comprehensive structural and functional assessment of internal organs. Recent innovations in data acquisition and processing can expand the clinical applications of MRI.
The Need A major limitation of MRI is slow data acquisition, which can compromise patient comfort, drive up costs, and increase susceptibility to motion. The clinical adoption of volumetric imaging for musculoskeletal and neuro applications, the growing demand for free-breathing real-time imaging …
  • College: College of Engineering (COE)
  • Inventors: Zhao, Shen; Ahmad, Rizwan; Potter, Lee
  • Licensing Officer: Randhawa, Davinder

Golden-shift Ordered Cartesian sampling (GOC) for Dynamic MRI (Free-breathing Accelerated MRI (Portfolio)
TS-062486 — Magnetic Resonance Imaging (MRI) is a versatile noninvasive imaging tool that is routinely used to evaluate many diseases and conditions. MRI offers exquisite soft tissue contrast and high spatial resolution to enable comprehensive structural and functional assessment of internal organs. Recent innovations in data acquisition and processing can expand the clinical applications of MRI.
The Need A major limitation of MRI is slow data acquisition, which can compromise patient comfort, drive up costs, and increase susceptibility to motion. The clinical adoption of volumetric imaging for musculoskeletal and neuro applications, the growing demand for free-breathing real-time imaging …
  • College: College of Engineering (COE)
  • Inventors: Ahmad, Rizwan; Jin, Ning; Liu, Yingmin; Simonetti, Orlando
  • Licensing Officer: Randhawa, Davinder

Mass Casualty Incident Virtual Reality Training Simulation
TS-062343 — The Need: In the face of mass casualty incidents, first responders play a critical role in saving lives and minimizing the impact of disasters. However, traditional training methods using mock patients or mannequin simulators for mass casualty triage are costly, challenging to replicate, and requir…
  • College: College of Arts & Sciences
  • Inventors: Price, Alan; Berezina-Blackburn, Vitalya; Oliszewski, Alex; Swearingen, Scott; Winegardner, Zachary
  • Licensing Officer: Dahlman, Jason "Jay"

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