# of Displayed Technologies: 3 / 3

Applied Category Filter (Click To Remove): Biologics


Thermogenic Biologicals for Obesity Treatment
TS-037747 — Identification and use of novel adipokines for reduction of visceral fat using thermogenesis.
Obesity as a result of an increase in intra-abdominal (or visceral) fat is an independent risk factor for major diseases such as type 2 diabetes and cardiovascular diseases. Risk is increased with higher levels of intra-abdominal fat due to increases in insulin resistance and chronic inflammation,…
  • College: College of Education & Human Ecology
  • Inventors: Ziouzenkova, Ouliana; Parquette, Jonathan
  • Licensing Officer: Flammang, Ann Marie

Engineering Calmodulin Proteins to Treat Ryanopathy-Associated Diseases
TS-032588 — Engineered calmodulin-based therapeutics for the treatment of cardiovascular diseases.
While there are three ryanodine receptors responsible for the release of calcium from intracellular stores during excitation-contraction, ryanodine receptor channel 2 (RyR2) has emerged as an important target in the treatment of cardiac failure. When RyR2 channels cease to effectively regulate int…
  • College: College of Medicine (COM)
  • Inventors: Davis, Jonathan
  • Licensing Officer: Paschall, Christopher

Co-inducer and Antibiotic-free Plasmid Addiction System
TS-014945 — A novel plasmid addiction system for cost-effective end-product generation.
The fermentative production of biobutanol through the use of Clostridium is a well-known process and utilized for production of solvents and fuels. However, problems with this method include difficulty in genetically manipulating native strains, scalability for industrial applications, and low yie…
  • College: College of Arts & Sciences
  • Inventors: Tabita, Fred; Laguna, Rick; Young, Sarah
  • Licensing Officer: Paschall, Christopher

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