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Thermogenic Compositions and Methods
TS-037747 — Biologicals for treatment of obesity related disease, including glucose intolerance and neurological disorders.
Worldwide obesity has tripled over the last 40 years and the incidence of overweight or obese populations is rising in low, middle, and high income countries. An increase in adipose tissue results in higher risk for cardiovascular disease and type 2 diabetes, which increase risk for Alzheimer&rsqu…
  • College: College of Education & Human Ecology
  • Inventors: Ziouzenkova, Ouliana; Parquette, Jonathan
  • Licensing Officer: Flammang, Ann Marie

Engineering Calmodulin Proteins to Treat Ryanopathy-Associated Diseases
TS-032588 — Engineered calmodulin-based therapeutics for the treatment of cardiovascular diseases.
While there are three ryanodine receptors responsible for the release of calcium from intracellular stores during excitation-contraction, ryanodine receptor channel 2 (RyR2) has emerged as an important target in the treatment of cardiac failure. When RyR2 channels cease to effectively regulate int…
  • College: College of Medicine (COM)
  • Inventors: Davis, Jonathan
  • Licensing Officer: Paschall, Christopher

Co-inducer and Antibiotic-free Plasmid Addiction System
TS-014945 — A novel plasmid addiction system for cost-effective end-product generation.
The fermentative production of biobutanol through the use of Clostridium is a well-known process and utilized for production of solvents and fuels. However, problems with this method include difficulty in genetically manipulating native strains, scalability for industrial applications, and low yie…
  • College: College of Arts & Sciences
  • Inventors: Tabita, Fred; Laguna, Rick; Young, Sarah
  • Licensing Officer: Dahlman, Jason "Jay"
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