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A novel STK1-targeted small molecule as an "antibiotic resistance breaker"
TS-037880 — Inh2-B1 serves as a therapeutically important “antibiotic-resistance-breaker,” which enhances the bactericidal activity of Ceftriaxone/Cefotaxime against highly pathogenic MDRSA infection.
Highly pathogenic and multidrug-resistant Staphylococcus aureus (MDRSA) encompasses methicillin-resistant strains of S. aureus that have developed resistance to multiple traditional antibiotics. Because of the recent emergence of antimicrobial resistance, MDRSA has been commonly incriminated in a …
  • College: College of Medicine (COM)
  • Inventors: Pancholi, Vijay
  • Licensing Officer: Davis, Stewart

Selective Delipidation of Mycobacterium bovis BCG enhances its Vaccine Potential against TB
TS-037463 — A novel method to increase vaccine effectiveness for TB
Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb), is an infectious disease that kills one person every 21 seconds. TB is the current leading cause of death worldwide due to a single infectious organism, overtaking AIDS and malaria. TB treatment requires several months to years of che…
  • College: College of Medicine (COM)
  • Inventors: Torrelles, Jordi; Moliva, Juan
  • Licensing Officer: Norris, Francis "Frank"

Novel bacterial Type II topoisomerase inhibitors for the treatment of bacterial infections
TS-037293 — Bacterial infections such as sexually transmitted diseases, meningitis, pneumonia, tuberculosis (TB), and tetanus are some of the most common infectious diseases. However, there are few drugs that can be used against all of these diseases, and several bacteria have developed resistance to many com…
  • College: College of Pharmacy
  • Inventors: Mitton-Fry, Mark
  • Licensing Officer: Flammang, Ann Marie

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