Available Technologies
# of Displayed Technologies: 8 / 8
Applied Category Filter (Click To Remove): Respiratory & Pulmonary, Asthma
Fibroblast-specific LNPs delivering A20 mRNA to treat idiopathic pulmonary fibrosis (IPF)
TS-075175 — Problem
Idiopathic pulmonary fibrosis (IPF) is a chronic disease where activated fibroblasts mediate the abnormal accumulation of extracellular matrix (ECM) in the lung interstitial space, leading to progressive impairment of pulmonary function. Current IPF therapies are associated with significant…
- College: College of Pharmacy (COP)
- Inventors: Dong, Yizhou; Kang, Diana; Wang, Chang; Yan, Jingyue
- Licensing Officer: He, Panqing
Novel extracellular vesicles loaded with anti-inflammatory agents for the treatment of pulmonary diseases
TS-075161 — Problem
Acute and chronic pulmonary inflammation conditions, such as acute respiratory distress syndrome (ARDS), acute lung injury (ALI) and asthma, remain a significant healthcare challenge with high mortality rates, long-term morbidity and a substantial economic burden due to prolonged hospital s…
- College: College of Medicine (COM)
- Inventors: Karpurapu, Manjula; Christman, John; Parinandi, Narasimham
- Licensing Officer: Willson, Christopher
Oxygen-Concentrating Self‑Rescuer (OCSR) for Confined‑Space Emergencies
TS-073264 —
Low‑oxygen, toxic environments created by fires or explosions in mines, tunnels, and enclosed spaces remain a leading cause of fatalities for trapped occupants and rescuers. Current self‑contained breathing and escape devices are constrained by limited oxygen supply, bulk, weight, heat generat…
- College: College of Engineering (COE)
- Inventors: Seidt, Jeremy; Brune, Ryan; Dutta, Prabir; Klein, Jerome
- Licensing Officer: Ashouripashaki, Mandana
Novel Extracellular Vesicles Loaded with Anti-Inflammatory Agents
TS-065154 — , 2018-345 Revolutionary treatment for ARDS using novel extracellular vesicles loaded with Anti-Inflammatory Agents.
The Need
Acute Respiratory Distress Syndrome (ARDS) remains a significant healthcare challenge with high mortality rates and long-term morbidity. Despite advancements in supportive care, there’s an urgent need for pharmacologic treatments targeting the molecular mechanisms driving ARDS pathog…
- College: College of Medicine (COM)
- Inventors: Karpurapu, Manjula; Christman, John; Parinandi, Narasimham
- Licensing Officer: Willson, Christopher
Automated Endotracheal Intubation
TS-062900 — This cutting-edge technology redefines the intubation process by guiding the endotracheal tube into the airway with exceptional precision.
The Need
Intubation is a critical medical procedure used to assist patients with breathing difficulties, executed through the insertion of an endotracheal tube (ET) into the windpipe. With over 313 million annual intubation procedures worldwide, ensuring first-pass success and minimizing complicati…
- College: College of Engineering (COE)
- Inventors: Ruegsegger, Mark; Elsayed-Awad, Hamdy; Hopping, Ethan; Lopez Vogler, Christian; Miles, Tim; Peiffer, Jordan
- Licensing Officer: Bhatti, Hamid
Transforming PAH Management with PHORA: Empowering Physicians for Better Patient Care
TS-062764 — The Pulmonary Hypertension Outcomes Risk Assessment (PHORA): a PAH risk stratification tool.
Pulmonary Arterial Hypertension (PAH) demands precise risk stratification for effective patient management. Clinical decision support tools can help inform treatment decisions made by physicians and other healthcare providers, usually at the point of care.
The Need
Current methods for assistin…
- College: College of Medicine (COM)
- Inventors: Benza, Ray; Lin, Shili; Mathur, Puneet
- Licensing Officer: Hampton, Andrew
Novel Live Attenuated Vaccines for Pneumoviruses
TS-037753 — A method to create vaccines for pneumoviruses, using recombinant viruses.
The Need
Pneumoviruses consist of pathogens that target the upper respiratory tract within their specific hosts. These include many important human and animal pathogens, such as human respiratory syncytial virus (hRSV), hMPV, bovine RSV, pneumonia virus of mice (PVM), and avian metapneumovirus (aMP…
- College: College of Veterinary Medicine (CVM)
- Inventors: Li, Jianrong; Cai, Hui; Peeples, Mark; Wang, Rongzhang
- Licensing Officer: Willson, Christopher
Novel Therapeutic for Influenza-Induced Acute Respiratory Distress Syndrome
TS-032198 — A parenteral administration of a naturally occurring chemical used to treat influenza-induced hypoxemia, lung dysfunction, and acute respiratory distress syndrome (ARDS). This treatment could also be potentially useful in treating ARDS from other causes.
Acute respiratory distress syndrome (ARDS) is a clinical syndrome characterized by impaired alveolar gas exchange, a symptom that leads to a lack of oxygen in the bloodstream. This lack of oxygen to vital organs can lead to organ failure and results in a high possibility of patient death. The infl…
- College: College of Veterinary Medicine (CVM)
- Inventors: Davis, Ian
- Licensing Officer: Willson, Christopher
