Protease-free Bacillus subtilis host
TS-065845 — The Need: In the realm of biotechnology, the challenge of synthesizing enzymes, pharmaceuticals, and fine chemicals efficiently is paramount. However, the presence of multiple proteases secreted by Bacillus subtilis 168 during growth stages poses a significant obstacle to achieving optimal productio…
- College: College of Arts & Sciences
- Inventors: Zeigler, Daniel
- Licensing Officer: Willson, Christopher
Drosophila melanogaster muscle stem cell line
TS-064271 — The Need
In the rapidly advancing landscape of life sciences, researchers and biotech companies face an escalating demand for reliable and versatile cell lines. The need for a specialized cell line that combines adaptability, reproducibility, and ease of use is paramount in accelerating breakthroug…
- College: College of Arts & Sciences
- Inventors: Simcox, Amanda
- Licensing Officer: Dahlman, Jason "Jay"
Primary Poultry Satellite Cells
TS-062405 — Primary Poultry Satellite cells
Primary Poultry Satellite cells
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Velleman, Sandra
- Licensing Officer: Dahlman, Jason "Jay"
Avian Breast Muscle Satellite Cells
TS-062404 — Pimary Avian Breast Muscle Satellite Cells
Primary Avian Breast Muscle Satellite Cells
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Velleman, Sandra
- Licensing Officer: Dahlman, Jason "Jay"
Primary Chicken breast muscle satellite cells
TS-062403 — Primary Chicken breast muscle satellite cells
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Velleman, Sandra
- Licensing Officer: Dahlman, Jason "Jay"
Genetic Method for Generating Continuous Cell Lines in Drosophila.
TS-062331 — The Need: Advancing Drosophila Cell Culture for Biological Research
In biological research, the analysis of cells in culture has been pivotal in advancing our understanding of various biological processes. However, the underdeveloped state of Drosophila cell culture has presented a challenge, as th…
- College: College of Arts & Sciences
- Inventors: Simcox, Amanda; Dequeant, Mary-Lee; Perrimon, Norbert
- Licensing Officer: Panic, Ana
Propionibacterium acidipropionici Knockout Mutant for Propionic Acid Fermentation
TS-062323 — The Need: In today's industrial landscape, the demand for sustainable and cost-effective bio-based chemicals continues to rise. Propionic acid, a valuable building block in various industries, including food, pharmaceuticals, and plastics, is no exception. However, conventional production method…
- College: College of Engineering (COE)
- Inventors: Yang, Shang-Tian "ST"
- Licensing Officer: Panic, Ana
LYMPHOBLASTIC LEUKEMIA/HIGH-GRADE LYMPHOMA miR155 TRANSGENIC MICE
TS-062319 — The Need
The urgent need to address lymphoproliferative disorders, including B cell malignancies such as acute lymphoblastic leukemia (ALL) and high-grade lymphomas, drives the demand for innovative and effective therapeutic approaches. These aggressive diseases, characterized by the uncontrolled p…
- College: College of Medicine (COM)
- Inventors: Croce, Carlo
- Licensing Officer: Willson, Christopher
Turkey pectoralis major satellite cells for production of clean meat
TS-052254 —
Increasing public awareness of social and environmental costs associated with the traditional meat industry has resulted in demand for animal-free alternatives. Clean meat (also called cell-based meat), is a meat product that is synthesized by tissue culture that mimics both the biochemical and cu…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Velleman, Sandra
- Licensing Officer: Dahlman, Jason "Jay"
Nras Mouse Melanoma Cell Lines
TS-049491 — Dr. Christin Burd's lab at The Ohio State University has developed a set of Nras-mutant mouse melanoma cell lines that can be used for preclinical tumor immunology and cancer biology studies.
Studies show that 15-30% of melanomas are Nras driven and 60% of melanomas are Braf driven. Dr. Christin Burd's lab at The Ohio State University has developed a set of Nras-mutant mouse melanoma cell lines that complement a set of Braf cell lines developed by Marcus Bosenberg at Yale Universit…
- College: College of Medicine (COM)
- Inventors: Burd, Christin; Murphy, Brandon
- Licensing Officer: Taysavang, Panya
Engineered Cells for Treatment of Animal Metabolic Disorders
TS-041976 — The implantation of engineered thermogenic cells for treating metabolic disease and obesity in animals.
Obesity remains one of the main underlying causes for many malignancies in domestic animals such as cats, dogs, and horses. From a veterinary perspective, obesity dramatically increases the risk of cancer, one of the leading causes of death in domesticated animals. Other diseases correlated with o…
- College: College of Education & Human Ecology
- Inventors: Ziouzenkova, Ouliana
- Licensing Officer: He, Panqing
Canine Lymphoma Cell Line
TS-015190 — A novel canine lymphoma cell line developed from the malignant pleural effusion of a dog with peripheral T-cell lymphoma.
Lymphoma is the most common life-threatening cancer of dogs, accounting for up to 24% of all malignancies and over 80% of all hematopoietic cancers. Spontaneously occurring lymphoma in the dog has many of the same histopathological, molecular, and clinical features as non-Hodgkin’s lymphoma …
- College: College of Veterinary Medicine
- Inventors: Kisseberth, William
- Licensing Officer: Dahlman, Jason "Jay"