Textile Sensors for Neonatal Growth and Safety
TS-073028 —
Neonatal units need unobtrusive, continuous monitoring of presence, posture, motion, and growth metrics (recumbent length, optional weight) without cameras, wires, or labor‑intensive workflows. Frequent, accurate measurements are critical for early detection of growth deviations and unsafe sleep…
- College: College of Engineering (COE)
- Inventors: Kiourti, Asimina; Militello, Lisa
- Licensing Officer: Ashouripashaki, Mandana
Strain‑Activated Programmable Surfaces for Controlled Drug Delivery in Mechanically Regulated Diseases
TS-072945 —
Many mechanically mediated conditions such as vascular hypertension, glaucoma, and abdominal distension, present intermittent, unpredictable episodes that demand drug release only when symptoms emerge. Conventional platforms often leak at baseline, require external triggers, or cannot synchronize …
- College: College of Engineering (COE)
- Inventors: Zhao, Yi
- Licensing Officer: Randhawa, Davinder
Sustainable Fungal Memristors for Neuromorphic and Eco-Friendly Computing
TS-072329 — The Need
The rapid growth of artificial intelligence and neural networks is driving unprecedented demand for energy-efficient, scalable hardware. Conventional memristors require rare earths and complex fabrication, contributing to electronic waste and limiting accessibility. There is a critical need…
- College: College of Engineering (COE)
- Inventors: LaRocco, John; Hill, Justin; Simonis, John; Tahmina, Qudsia
- Licensing Officer: Randhawa, Davinder
Flexible Light-Addressable Sensor for High-Resolution Physiological Mapping
TS-072319 — The Need
Current methods for mapping electrical potential gradients in biological tissues, such as the brain, rely on high-density electrode arrays fabricated via costly microfabrication techniques. These rigid devices struggle to conform to complex tissue morphologies, limiting their effectiveness …
- College: College of Engineering (COE)
- Inventors: Li, Jinghua; Chen, Shulin; Jia, Yizhen; Liu, Tzu Li; Wang, Qi
- Licensing Officer: Ashouripashaki, Mandana
Wearable Magnetoinductive Smart Textiles for Real-Time Muscle Health Monitoring
TS-072052 — The Need
Current wearable sensors for muscle health are limited in their ability to track real-time geometric changes in muscle size and shape, especially outside controlled laboratory environments. Existing solutions, such as force myography and ultrasound, either lack direct geometric insight or a…
- College: College of Engineering (COE)
- Inventors: Coogle, Sam; Kiourti, Asimina
- Licensing Officer: Randhawa, Davinder
Breakthrough In Delivery: Expanding Access to Intracellular Targets for Next-Generation Therapies
TS-072004 — Empower your pipeline with a versatile platform for efficient, customizable biomolecule transport.
Overview
Intracellular delivery remains a persistent challenge in drug delivery, gene editing, and biotechnology. Pharmaceutical and biotech companies lose valuable opportunities when promising drugs and biologics cannot reach their intended targets inside cells, limiting product effectiveness and m…
- College: College of Arts & Sciences
- Inventors: Bong, Dennis
- Licensing Officer: Panic, Ana
Free Energy Spectroscopy: Transforming Molecular Analytics for Next-Generation Biotech and Pharma
TS-071946 — Powering faster, smarter decisions with real-time molecular insights for research and therapeutic development.
Overview
Pharmaceutical and biotech companies often face delays and uncertainty in new drug development due to insufficient experimental insight into the shifting behaviors of large biomolecular complexes— processes critical to understanding disease and drug mechanisms. Free Energy Spectrosco…
- College: College of Arts & Sciences
- Inventors: Poirier, Michael; Bonin, Kalven; Bundschuh, Ralf; Castro, Carlos
- Licensing Officer: Panic, Ana
Quantum Defect-Based Ultra-Sensitive Radiation Detection Platform
TS-071847 — The Need
Current fast neutron detection technologies suffer from inherently low sensitivity due to the limited interaction cross-section between neutrons and atomic nuclei. This restricts their effectiveness in critical applications such as nuclear security, radiation dosimetry, and advanced imaging…
- College: College of Engineering (COE)
- Inventors: Cao, Lei Raymond; Johnston-Halperin, Ezekiel; Shoen, Luke
- Licensing Officer: Ashouripashaki, Mandana
Smart Blueberry Extract: The Modern Natural Health Solution for Inflammation Relief and Wellness
TS-071830 — Unlocking plant-powered solutions to deliver effective inflammation relief and enhance disease outcomes.
Overview
Chronic inflammation driven by elevated interleukin-11 (IL-11) is a critical underlying cause of tissue scarring and cancer, worsening the disease outcomes over time. Current anti-inflammatory options fall short, offering limited control over IL-11 and failing to stop its persistent buildu…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Giusti, M. Monica; Prasher, Harmeen; Sellers, Patrick; Ziouzenkova, Ouliana
- Licensing Officer: Panic, Ana
Reversible Shape-Changing Amorphous Polymers via Liquid Crystal Templating
TS-071745 — The Need
Current two-way shape memory polymers (SMPs) require expensive, crystalline or liquid crystalline monomers and complex synthesis, limiting their use in cost-sensitive and biocompatible applications. Widely used amorphous polymers (e.g., polystyrene, PMMA) are inexpensive and common in con…
- College: College of Engineering (COE)
- Inventors: Wang, Xiaoguang "William"; Dupont, Robert; Zhang, Meng
- Licensing Officer: Randhawa, Davinder
NeuroThread: Ultrathin Wire-Type Neurochemical Sensor for Real-Time CNS Monitoring
TS-071414 — The Need
Current neurochemical monitoring technologies are limited by bulky form factors, complex fabrication, and invasiveness, which restrict their clinical and research utility. Existing sensors often cause tissue damage, lack real-time resolution, and are costly to manufacture, impeding widespre…
- College: College of Engineering (COE)
- Inventors: Li, Jinghua; Liu, Tzu Li
- Licensing Officer: Ashouripashaki, Mandana
Instant Diagnostics, Anywhere
TS-070543 — A Platform for High-Throughput Biomarker Detection that is portable, fast, and requires minimal sample
The Need
The diagnostics market is under increasing pressure to deliver faster, more reliable, and less invasive solutions, driven by growing global health challenges. Current technologies face critical limitations, including large sample requirements, labor-intensive workflows, and reliance on exp…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Seth, Ayesha; Zerrudo, Stephanee
- Licensing Officer: Panic, Ana
Method to Determine Tremor Frequency from Deep Brain Stimulation Signals
TS-070304 — The Need
Current clinical methods for assessing tremor severity in patients with Parkinson’s disease and other movement disorders rely heavily on subjective, qualitative observations, such as evaluating hand-drawn spirals or observing motor tasks. These approaches lack precision, are difficult…
- College: College of Engineering (COE)
- Inventors: Khan, Furrukh; Dalm, Brian; Novikov, David; Thomas, Evan; Zhao, Jessie
- Licensing Officer: Randhawa, Davinder
Motion-Guided Deep Image Prior (M-DIP) for Dynamic Image Reconstruction in Cardiovascular MRI
TS-069527 — The Need
Cardiovascular MRI (CMR) data acquisition is often time-consuming and relies on complex reconstruction methods that do not fully exploit the spatial and temporal structure of CMR data. There is a need for a more efficient, unsupervised approach that can accelerate CMR imaging while maintai…
- College: College of Engineering (COE)
- Inventors: Ahmad, Rizwan; Chen, Chong; Sultan, Muhammad
- Licensing Officer: Randhawa, Davinder
A new modular format for bispecific antibody fragments
TS-068425 — Functionalization of scFvs with cyclic peptide linkers
The Need
The high specificity of antibodies has been utilized to develop numerous technologies, tools and therapeutics, like ADCs and radiopharmaceuticals. Engineered antibody fragments like single-chain variable fragments (scFvs) are starting to see their way into the clinic in BiTEs and CAR T. Sc…
- College: College of Arts & Sciences
- Inventors: Magliery, Thomas; Do, Jamie; Han, Jeong Min "Mina"; Zhu, Ian
- Licensing Officer: Panic, Ana
Noninvasive Rapid Radiation Exposure Assay
TS-068290 — The Need
Radiation exposure poses significant health risks, including cancer and other illnesses, making it crucial for clinicians to accurately measure and assess the extent of radiation exposure. Existing methods often require invasive procedures and may not detect exposure at lower dose ranges.
…
- College: College of Arts & Sciences
- Inventors: Schultz, Zachary; Jacob, Naduparambil; Morder, Courtney; Witte, Spencer
- Licensing Officer: Panic, Ana
RAFT Agents for Controlled Radical Polymerization of Biofunctionalized Polymeric Materials
TS-068081 — These RAFT agents enable synthesis of novel polymer materials with enhanced biocompatibility and tailored functionality, suited for a wide range of biomedical applications.
Background
The growing demand for biofunctionalized polymer materials in fields such as drug delivery and diagnostics requires precise control over polymer properties. However, current reagents for Reversible Addition Fragmentation chain Transfer (RAFT) polymerization struggle with achieving the ne…
- College: College of Arts & Sciences
- Inventors: Kulkarni, Anuja; Watkins, Davita
- Licensing Officer: Panic, Ana
Wearable Coils for Monitoring Human Body Kinematics
TS-067943 — Monitoring human physiological functions and performance during real-time activities is becoming increasingly popular in sporting and healthcare environments. Many studies now suggest that the quantitative evaluation of kinetic parameters, joint range of motion, heart rate, and breathing rate can be…
- College: College of Engineering (COE)
- Inventors: Kiourti, Asimina; Mishra, Vigyanshu
- Licensing Officer: Randhawa, Davinder
Non-Contact Magnetocardiography for Measuring Cognitive Workload
TS-067810 — Work environments and other brain-intensive activities impose high demands on the cognitive and cerebral resources required to process vast amounts of information. This high demand can expose individuals to cognitive overload, which can be dangerous for their health and lead to errors and accidents.…
- College: College of Engineering (COE)
- Inventors: Kiourti, Asimina; Zhu, Keren
- Licensing Officer: Randhawa, Davinder
Neonatal Blood Vessel Locator for Vascular Access Procedures
TS-067796 — A handheld device for identifying preterm blood vessels in neonatal ICU.
Over 300,000 preterm births in the United States occur annually, representing 10.5% of all live births. Most preterm births occur spontaneously, but some result from medical conditions like infections or pregnancy complications requiring early labor induction or cesarean delivery. Common causes of p…
- College: College of Engineering (COE)
- Inventors: Metzler, Sandra; Bresolin, Alejandro; Crawford, Mackenzie; Fernandes, Siddharth; Hardin, Rene; Patel, Aarti; Richards, Hannah; Trainor, Dylan
- Licensing Officer: Sharick, Joe
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