TS-064046 — Dermal substitute with engineered rete ridges improves epidermal-dermal communication and enhances burn wound treatment.

TS-063963 — The Need In the dynamic realm of space exploration, the imperative to sustain life during extended missions places a critical demand on understanding the impact of spaceflight on plant growth. Traditional DNA sequencing methods employed by NASA fall short when dealing with plant material, necessita…

TS-063959 — The Need Millions of individuals suffer from constipation due to the inability to relax pelvic floor muscles during bowel movements, leading to discomfort and strained efforts. Current solutions, like the Squatty Potty, lack adjustability and portability, limiting their effectiveness for a diverse …

TS-063919 — An articulating end effector for additive manufacturing that utilizes robot-assisted endoscopic surgery to implant synthetic tissues at local defects through “keyhole” incisions in patients. This innovative technology T2019-145 is part of a portfolio that also includes T2017-363. To learn more about both technologies, please visit https://oied.osu.edu/find-technologies and search using the phrase: Endoscopic additive manufacturing of biomaterials.

TS-063547 — Novel small molecule STK1 inhibitors that “break” the resistance of bacteria strains to antibiotics.

TS-063471 — In an increasingly digital world, the demand for efficient and reliable photodetectors is paramount. These devices are critical for a variety of applications, from medical imaging to defense systems. However, traditional photodetectors often struggle with low UV-visible rejection, limiting their e…

TS-063433 — A new pharmacologic modality for treating AFib.

TS-063238 — A novel regularization technique applicable for medical imaging applications that leverages conditional generative adversarial networks (cGANs) to generate reconstructed images in significantly shorter timeframes. The Need Several techniques are used for image reconstruction in the medical aren…

TS-063237 — Electronic Health Records (EHR) are used in over 88% of all US medical clinics to improve care and streamline data. In addition, they enable sharing of data to multiple providers dealing with the same patient, thereby enhancing efficiency and care. The Need In the last decade, medical practices…

TS-063212 — When a patient demonstrates signs of imminent clinical deterioration, it is essential to immediately assess and treat the patient to prevent intensive care unit transfer, cardiac arrest, or death. These tasks often include transferring the patient to other facilities with optimal capabilities. T…

TS-063154 — Worldwide, 686,000 new head and neck (H&N) cancers are diagnosed yearly, and 375,000 people will die annually. Human papillomavirus (HPV) is responsible for an increasing subset of H&N malignancies called oropharyngeal squamous cell carcinomas (OPSCC). Although it has a better prognosis than…

TS-063091 — A gene therapy approach to address the specific needs of failing hearts.

TS-063006 — Medical device for vascular surgery and directed drug delivery

TS-062900 — This cutting-edge technology redefines the intubation process by guiding the endotracheal tube into the airway with exceptional precision.

TS-062822 — Humanized Antibody-drugs conjugate for chemo-immunotherapy of multiple cancer types

TS-062762 — Pinpointing previously concealed sectoral differences in the diabetic retina to diagnose DR earlier.

TS-062739 — Method to program pericytes for axon regeneration and spinal cord injury repair.

TS-062715 — Radiopaque biodegradable polymer for the tracking of the breast tissue tumor cavity after lumpectomy and other radiation therapy applications

TS-062693 — Dynamic AVF flow control: A paradigm shift in vascular access management for hemodialysis patients.

TS-062690 — Novel niclosamide analogues with improved bioavailability and mitigated dose-limiting toxicities.

TS-062688 — Conditioned neutrophils and cell therapy vectors for nerve regeneration

TS-062685 — Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths. The most common cancers are breast, lung, colon and rectum and prostate cancers. The Need Current cancer treatments mainly rely on chemotherapy, radiation, surgery and bon…

TS-062682 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately 40% living the first-year post-diagnosis and 17% in the second year. The Need Oncolytic viruses (OVs) are a prom…

TS-062681 — According to the American Cancer Society, breast cancer is the most common cancer for women in the US, except for skin cancer. It comprised about 30% of all new female cancers each year. While breast cancer death rates have decreased over the last several decades, it remains the second leading cause…

TS-062680 — According to the American Cancer Society, breast cancer is the most common cancer for women in the US, except for skin cancer. It comprised about 30% of all new female cancers each year. While breast cancer death rates have decreased over the last several decades, it remains the second leading cause…

TS-062679 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately 40% living the first-year post-diagnosis and 17% in the second year. The Need Oncolytic viruses (OVs) are a prom…

TS-062678 — Neurodegenerative diseases including Alzheimer's and Parkinson’s diseases, amyotrophic lateral sclerosis (ALS), prion diseases, and among others affect millions of people in the US. These diseases are relentless, often fatal, and affect fundamental functions – things like moving, bre…

TS-062677 — Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths. The most common cancers are breast, lung, colon and rectum and prostate cancers. The Need Current cancer treatments mainly rely on chemotherapy, radiation, surgery and bon…

TS-062628 — More than a billion people worldwide suffer from some neurological disorders, such as Alzheimer's, Parkinson's, multiple sclerosis, epilepsy, stroke, autism, addiction, and many others. These conditions result in more than 7 million deaths, with associated costs exceeding $1.5 trillion annua…

TS-062627 — Magnetic Resonance Imaging (“MRI”) is one of the most important modern medical imaging modalities. It has far less risk of side effects than most other imaging modalities. Generally, a high quality image requires high signal-to-noise ratio, high contrast between normal and pathological t…