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IR Precision: Revolutionizing Colorectal Cancer Metastasis Diagnosis with the CCML Library
TS-064834 — The Need: Colorectal cancer remains a significant global health challenge, particularly when it metastasizes to the liver. Accurate and rapid diagnosis of metastatic liver lesions is crucial for effective treatment planning and patient outcomes. Traditional diagnostic methods often lack the specific…
  • College: College of Arts & Sciences
  • Inventors: Coe, James; Allen, Heather; Bradley, Rebecca; Hitchcock, Charles; Martin, Edward
  • Licensing Officer: Willson, Christopher

Magnetic Nanoparticles for Cancer Cell Classification
TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year. The Need Developing drugs for cance…
  • College: College of Arts & Sciences
  • Inventors: Schultz, Zachary; Rist, David; Skardal, Aleksander; Venere, Monica
  • Licensing Officer: Willson, Christopher

Network-based Approach for Accurate Brain Modeling
TS-062628 — More than a billion people worldwide suffer from some neurological disorders, such as Alzheimer's, Parkinson's, multiple sclerosis, epilepsy, stroke, autism, addiction, and many others. These conditions result in more than 7 million deaths, with associated costs exceeding $1.5 trillion annua…
  • College: College of Arts & Sciences
  • Inventors: Cranmer, Skyler; Bhamidi, Shankar; Denny, Mathew; Desmarais, Bruce; Lu, Zhong-Lin; Stillman, Paul; Wilson, James
  • Licensing Officer: Dahlman, Jason "Jay"

Methods and Apparatus to Improve MRI Efficiency
TS-062627 — Magnetic Resonance Imaging (“MRI”) is one of the most important modern medical imaging modalities. It has far less risk of side effects than most other imaging modalities. Generally, a high quality image requires high signal-to-noise ratio, high contrast between normal and pathological t…
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua
  • Licensing Officer: Panic, Ana

Visual Function Mapping Technology: Enhancing Vision Care and Diagnostics
TS-062335 — The Need: In the field of ophthalmology and vision care, there is a critical need for accurate and comprehensive measurements of visual function over the entire visual field. Conditions such as glaucoma, age-related macular degeneration (AMD), diabetes, stroke, pituitary disease, brain tumors, and n…
  • College: College of Arts & Sciences
  • Inventors: Lu, Zhong-Lin; Lesmes, Luis; Xu, Pengjing "PJ"; Yu, Deyue
  • Licensing Officer: Dahlman, Jason "Jay"

An AI Solution for Mobile Stroke Detection for TeleMedicine, Hospital and Paramedic Use
TS-060782 — Problem Statement: Diagnosis of arterial occlusion and an associated stroke can be lengthy, delaying patient access to treatment. As large vessel occlusions account for 24 to 46% of acute ischemic strokes and may require treatment in a comprehensive stroke center, early diagnosis is key. Solution:…
  • College: College of Engineering (COE)
  • Inventors: Yilmaz, Alper; Gulati, Deepak Kumar
  • Licensing Officer: Hampton, Andrew

Automated Detection of Tumor Budding in Colorectal Cancer
TS-039267 — A non-invasive and automated tumor budding image analysis system for colorectal cancer. This program can detect tumor buds in traditional H&E stained sections without the need for manual assessment.
Colorectal cancer is the third most commonly diagnosed cancer in the United States. With a survival rate of less than 65%, early detection and treatment are key factors in survival. Tumor budding, associated with higher tumor stage, lymph node metastasis, and decreased disease-free survival, has e…
  • College: College of Medicine (COM)
  • Inventors: Gurcan, Metin; Ahmad Fauzi, Mohammad Faizal; Chen, Wei "Wei"; Frankel, Wendy
  • Licensing Officer: Hampton, Andrew

At-Home Digital Platform for Scoring Skin Disease
TS-038429 — An automated image analysis system for the recognition and quantification of skin disease
Acne and rosacea are skin diseases that affect around 85% of individuals, the former being the most common skin condition afflicting up to 50 million people. There is no gold standard for evaluation of these skin diseases, and their treatment efficacy is generally determined according to a poorly …
  • College: College of Medicine (COM)
  • Inventors: Kaffenberger, Benjamin; Gurcan, Metin
  • Licensing Officer: Hampton, Andrew

Design and apparatus for efficient measurement of the time course of perceptual sensitivity change
TS-037470 — A novel method of measuring the time course of degradation of perceptual sensitivity due to disease
Perception is the biological process that allows humans to differentiate external stimuli such as shapes and colors. Certain diseases affect perceptual sensitivity, usually resulting in a slow but measurable degrade in skill that correlates with the progression of the disease. Existing methods to …
  • College: College of Arts & Sciences
  • Inventors: Lu, Zhong-Lin; Lesmes, Luis; Zhao, Yukai
  • Licensing Officer: Dahlman, Jason "Jay"

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