# of Displayed Technologies: 8 / 8

Applied Category Filter (Click To Remove): Drug Discovery


Precision RNA-PROTACs: Revolutionizing Therapeutic Targeting of Dysregulated Ribonucleoprotein Complexes
TS-065457 — The Need: In the realm of therapeutic development, there's a pressing need for precise targeting of dysregulated ribonucleoprotein (RNP) complexes to combat various diseases, particularly neurodegenerative disorders like ALS, Alzheimer’s, and Huntington’s diseases. Traditional metho…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"; Strong, Rebekah
  • Licensing Officer: Willson, Christopher

Revolutionizing RNA-Protein Interaction Mapping: Precision Proximity Labeling Technology
TS-065456 — The Need In modern biological research, there is a pressing demand for technologies that enable precise mapping of RNA-protein interactions within Ribonucleoprotein (RNP) complexes. Traditional methods often lack the capability to pinpoint these interactions at the level of secondary structure moti…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"
  • Licensing Officer: Willson, Christopher

COLMARppm: web-server tool for prediction of NMR chemical shifts
TS-064585 — COLMARppm offers a swift and accurate solution to the longstanding challenges in metabolomics research. Unique features and capabilities position it as a crucial tool for researchers seeking to unlock unknown metabolites, contributing to health research The Need In the field of metabolomics resear…
  • College: College of Arts & Sciences
  • Inventors: Bruschweiler, Rafael; Li, Dawei "Dawei"; Rigel, Nick
  • Licensing Officer: Dahlman, Jason "Jay"

A modified intein for temperature sensitive applications
TS-063697 — Controlled Protein Release Over a Broad Range of Temperatures
The Need: In the biotechnology field, the demand for efficient protein purification methods and innovative drug delivery solutions is ever-growing. Researchers and companies require technologies that can streamline the purification process, ensuring high yields and purity, while offering versatile …
  • College: College of Engineering (COE)
  • Inventors: Wood, David; Coolbaugh, Michael; Stimple, Samuel "Sam"; Yuan, Hongyu
  • Licensing Officer: Dahlman, Jason "Jay"

Advanced AAV Gene Therapy Characterization Technique
TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …
  • College: College of Arts & Sciences
  • Inventors: Wysocki, Vicki; Cleary, Sean; Du, Chen
  • Licensing Officer: Dahlman, Jason "Jay"

Revolutionizing Cancer Research: Unveiling the Dynamics of K-Ras for Targeted Therapies
TS-062433 — The Need: Understanding the intricate functions of the K-Ras protein is crucial in combating various types of human cancer. However, the lack of detailed atomic-level information has hindered progress in this area, leaving significant gaps in our comprehension of its roles in health and disease. Th…
  • College: Enterprise for Research, Innovation and Knowledge (ERIK)
  • Inventors: Bruschweiler, Rafael; Bruschweiler-Li, Lei "Lei"; Hansen, Alexandar "Alex"; Xiang, Xinyao; Yuan, Chunhua
  • Licensing Officer: Dahlman, Jason "Jay"

Ion Carpet-Based Surface-Induced Dissociation Device
TS-062342 — The Need In the field of mass spectrometry (MS), the study of proteins and protein complexes in their native form, known as native MS, has become crucial in understanding their structure and function. However, the current collision-induced dissociation (CID) technique used in tandem MS experiments …
  • College: College of Arts & Sciences
  • Inventors: Wysocki, Vicki; Gilbert, Joshua; Stiving, Alyssa
  • Licensing Officer: Dahlman, Jason "Jay"

AI-Enabled Retrosynthesis for Drug Development
TS-060092 — AI methods and systems for predicting reactants and their synthesis paths to support drug design and chemical synthesis.
A time-consuming and costly step in drug development is the identification of drug-like small molecules that display desired properties against a specific biomolecular target and then the synthesis of such molecules if they do not exist. Retrosynthesis is a procedure where such a desired molecule i…
  • College: College of Medicine (COM)
  • Inventors: Ning, Xia; Chen, Ziqi
  • Licensing Officer: Hampton, Andrew

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