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Wireless Sensor-Actuator-Coupled Gustatory Interface for Remote Tasting
TS-072321 — The Need Current virtual and augmented reality (VR/AR) platforms lack integration of gustatory (taste) sensations, limiting user immersion and sensory engagement. Existing human-machine interfaces focus primarily on visual, auditory, and haptic feedback, neglecting the chemical dimension of taste. T…
  • College: College of Engineering (COE)
  • Inventors: Chen, Shulin; Jia, Yizhen; Li, Jinghua; Liu, Tzu-Li
  • Licensing Officer: Ashouripashaki, Mandana

Flexible Light-Addressable Sensor for High-Resolution Physiological Mapping
TS-072319 — The Need Current methods for mapping electrical potential gradients in biological tissues, such as the brain, rely on high-density electrode arrays fabricated via costly microfabrication techniques. These rigid devices struggle to conform to complex tissue morphologies, limiting their effectiveness …
  • College: College of Engineering (COE)
  • Inventors: Li, Jinghua; Chen, Shulin; Jia, Yizhen; Liu, Tzu Li; Wang, Qi
  • Licensing Officer: Ashouripashaki, Mandana

Mesoporous Support-Immobilized Metal Oxide Nanoparticles for High-Purity Syngas Generation
TS-071809 — The Need Syngas is an essential intermediate for producing high-value chemicals such as gasoline, methanol, and dimethyl ether. Current industrial methods (steam reforming, autothermal reforming, and partial oxidation) are energy-intensive, costly, and environmentally burdensome. Moreover, these met…
  • College: College of Engineering (COE)
  • Inventors: Fan, Liang-Shih; Cheng, Zhuo; Liu, Yan; Qin, Lang
  • Licensing Officer: Ashouripashaki, Mandana

Redox Chemical Looping System for CO2 Capture and Syngas Generation
TS-071808 — The Need Industrial syngas and hydrogen production processes are highly energy-intensive and contribute significantly to carbon emissions due to reliance on fossil fuel combustion. Existing methods require multiple unit operations, resulting in low efficiency and high operational costs. There is a c…
  • College: College of Engineering (COE)
  • Inventors: Fan, Liang-Shih; Baser, Deven Swapneshu; Cheng, Zhuo; Shah, Vedant
  • Licensing Officer: Ashouripashaki, Mandana

Stable Phase Metal Oxide Syngas Generation without Molecular Oxygen
TS-071806 — The Need Current syngas production from methane relies on energy-intensive air separation units (ASUs) to supply molecular oxygen, driving up capital and operating costs. Conventional catalysts also suffer from carbon deposition at low oxidant concentrations, limiting process flexibility and efficie…
  • College: College of Engineering (COE)
  • Inventors: Fan, Liang-Shih; Baser, Deven; Cheng, Zhuo; Kathe, Mandar; Kong, Fanhe "Frank"; Nadgouda, Sourabh; Tong, Andrew
  • Licensing Officer: Ashouripashaki, Mandana

Smart Liquid Crystal Sensor for Real-Time Shear Flow Visualization
TS-070520 — The Need Accurate, real-time mapping of shear forces in fluid environments remains a challenge, particularly in applications requiring passive, non-invasive, and long-term monitoring. Existing technologies often rely on active sensors that require power, are difficult to integrate into sensitive sys…
  • College: College of Engineering (COE)
  • Inventors: Wang, Xiaoguang "William"; Chen, Boyuan; Kara, Ufuoma; Weible, Alan
  • Licensing Officer: Randhawa, Davinder

Crate Rail System: Space-Efficient and Accessible Crate-Based Storage for Any Environment
TS-069694 — A compact, modular, and aesthetic storage solution for milk crates, designed to optimize space and improve accessibility in various environments.
Background Milk crates are a standardized, versatile storage option commonly used for goods transportation and organization. Current storage methods, such as stacking or standalone shelving, hinder accessibility, lack aesthetic appeal, and occupy significant floor space, particularly in environment…
  • College: College of Arts & Sciences
  • Inventors: Nickley, William; King, Hannah; Seal-Roth, Jack; Straughn, Emily; Zhang, Jiacheng
  • Licensing Officer: Panic, Ana

Motion-Guided Deep Image Prior (M-DIP) for Dynamic Image Reconstruction in Cardiovascular MRI
TS-069527 — The Need Cardiovascular MRI (CMR) data acquisition is often time-consuming and relies on complex reconstruction methods that do not fully exploit the spatial and temporal structure of CMR data. There is a need for a more efficient, unsupervised approach that can accelerate CMR imaging while maintai…
  • College: College of Engineering (COE)
  • Inventors: Ahmad, Rizwan; Chen, Chong; Sultan, Muhammad
  • Licensing Officer: Randhawa, Davinder

A Scalable Method for Minimizing Beam-Training Overhead in mmWave Communications
TS-068475 — The Need As mmWave technology becomes the backbone of 5G and other advanced communication systems, the demand for fast, reliable, and scalable beamforming solutions has surged. Traditional beam-training methods are computationally intensive and time-consuming, leading to delays in establishing high-…
  • College: College of Engineering (COE)
  • Inventors: Athreya, Kannan; Chen, Wei-Han; Liu, Xin; Parthasarathy, Srinivasan
  • Licensing Officer: Randhawa, Davinder

Self-Calibration Technique for mmWave Antenna Arrays Based on Everyday Communication Behaviors
TS-068472 — The Need The increasing adoption of mmWave technologies in 5G, IoT, and other advanced communication networks highlights a critical need for cost-effective, efficient, and scalable antenna calibration solutions. Traditional calibration methods rely on expensive laboratory setups and specialized equi…
  • College: College of Engineering (COE)
  • Inventors: Athreya, Kannan; Chen, Wei-Han; Liu, Xin
  • Licensing Officer: Randhawa, Davinder

Advanced Sensor Arrays for Precise Gas Identification and Analysis
TS-066250 — A cutting-edge sensor system featuring p-n junctions in MOS materials for accurate detection and identification of gases.
In various industries, there is a growing demand for highly selective and sensitive gas sensors capable of accurately identifying specific gases within complex mixtures, addressing challenges in environmental monitoring, industrial safety, and healthcare diagnostics. This innovative sensor syst…
  • College: College of Arts & Sciences
  • Inventors: Dutta, Prabir; Govindhan, Maduraiveeran; Mondal, Suvra; Sun, Chenhu
  • Licensing Officer: Dahlman, Jason "Jay"

Revolutionary NO Sensor for Highly Selective and Sensitive Gas Detection
TS-066249 — A novel sensor leveraging WO3 and Cr2O3 for selective NO detection in harsh environments and breath analysis with high sensitivity at ppb levels.
There is a critical demand for advanced gas sensors capable of selectively detecting nitric oxide (NO) in diverse applications such as environmental monitoring, industrial processes, and medical diagnostics, particularly in challenging environments with interfering gases like carbon monoxide (CO).…
  • College: College of Arts & Sciences
  • Inventors: Dutta, Prabir; Govindhan, Maduraiveeran; Mondal, Suvra; Sun, Chenhu
  • Licensing Officer: Dahlman, Jason "Jay"

Three-dimensional cellular automation codes for solidification microstructure and porosity simulation of multi-component alloys
TS-063911 — Porosity formation during the solidification of aluminum-based alloys, induced by hydrogen gas and alloy shrinkage, presents a significant challenge for industries relying on high-performance solidification products such as castings, welds, and additively manufactured components. This issue advers…
  • College: College of Engineering (COE)
  • Inventors: Luo, Alan; Gu, Cheng
  • Licensing Officer: Zinn, Ryan

Suppressing background carbon incorporation using laser-assisted MOCVD growth of nitride-based semiconductors
TS-063717 — The Need In the world of semiconductor material systems, the demand for advancements in optoelectronic and power electronic devices is ever-growing. The fabrication of semiconductor films, crucial for these applications, primarily relies on epitaxy technologies such as hydride vapor phase epitaxy (…
  • College: College of Engineering (COE)
  • Inventors: Zhao, Hongping; Chen, Zhaoying; Zhang, Yuxuan
  • Licensing Officer: Randhawa, Davinder

Single-Input Broadband Doherty-HDmax Continuum Power Amplifier
TS-063156 — In the era of 5G and beyond, wireless base station infrastructures require power amplifiers (PAs) that maintain high efficiency from backoff to peak power level. Conventional Doherty PAs, while popular, are inherently narrowband due to their reliance on a quarter-wave transmission line (TL). This …
  • College: College of Engineering (COE)
  • Inventors: Roblin, Patrick; Liang, Chenyu
  • Licensing Officer: Ashouripashaki, Mandana

A Novel MIMO Architecture for Multi-user Power line communication
TS-062843 — This MIMO-PLC architecture is the first scalable MIMO architecture on a single power line. It improves the throughput for power line communication (PLC) by utilizing the existing power delivery infrastructure and allows for high data rates in rural areas.
Home networking and the Internet of Things (IoT), especially voice and video communications, require high throughput, reliable coverage, and sustainable connectivity. However, the performance is dramatically decreased when the wireless signals go through the walls and ceilings. The densely deploye…
  • College: College of Engineering (COE)
  • Inventors: Athreya, Kannan; Chen, Bo; Guruvenkata, Vivek; Sun, Wei
  • Licensing Officer: Mess, David

Addressing the Challenges in HCC Treatment with Innovative Technology
TS-062690 — Novel niclosamide analogues with improved bioavailability and mitigated dose-limiting toxicities.
Hepatocellular carcinoma (HCC) poses a significant global health challenge, being a predominant form of liver cancer with high mortality rates. The disease exhibits sexual dimorphism, disproportionately affecting males. The Need Despite the crucial role of androgen receptors (AR) in HCC progress…
  • College: College of Pharmacy
  • Inventors: Coss, Christopher; Cheng, Jeffrey; Cheng, Xiaolin; Kulp, Samuel; Li, Tom; Montgomery, Emma; Xing, Enming
  • Licensing Officer: Willson, Christopher

Transducin β-like protein 1 X-Linked Selective Degraders as Anti-cancer Therapeutics
TS-062685 — Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths. The most common cancers are breast, lung, colon and rectum and prostate cancers. The Need Current cancer treatments mainly rely on chemotherapy, radiation, surgery and bon…
  • College: College of Pharmacy
  • Inventors: Cheng, Xiaolin; Alinari, Lapo; Li, Pui-Kai "Tom"; Yang, Rui
  • Licensing Officer: Willson, Christopher

Advanced AAV Gene Therapy Characterization Technique
TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …
  • College: College of Arts & Sciences
  • Inventors: Wysocki, Vicki; Cleary, Sean; Du, Chen
  • Licensing Officer: Dahlman, Jason "Jay"

Dual Androgen Receptor/AKR1C3 Inhibitors for Prostate Cancer
TS-062605 — The Need: Castration-resistant prostate cancer (CRPC) poses a significant challenge in oncology, with existing therapies often leading to resistance and disease progression. Key drivers of resistance include the androgen receptor (AR) and aldo-keto reductase family 1 member C3 (AKR1C3). Novel treat…
  • College: College of Pharmacy
  • Inventors: Li, Pui-Kai "Tom"; Cheng, Xiaolin; Kong, Xiaotian; Xing, Enming
  • Licensing Officer: Schworer, Adam

RF Energy Harvesting Wireless Mobile Device Charger
TS-062601 — Only a small fraction of the radio frequency (RF) energy transmitted by smartphones and other wireless devices is used to communicate with a wireless access point. It would be useful to collect or harvest the unused RF signals in order to convert them to direct current (DC) power and supplement th…
  • College: College of Engineering (COE)
  • Inventors: Chen, Chi-Chih; Koksal, C. Emre; Shroff, Ness; Tallos, Roland
  • Licensing Officer: Zinn, Ryan

Passive RF Rectifier Circuit Design with Harmonic Harvester
TS-062596 — Conventional rectifying circuit designs convert alternating-current (AC) signals into direct-current (DC) signals via the used of diodes. Low-barrier Schottky diodes are used in low AC power cases such as with ambient radio frequency (RF) signals. Ideally, each diode is only turned on during the p…
  • College: College of Engineering (COE)
  • Inventors: Chen, Chi-Chih
  • Licensing Officer: Zinn, Ryan

Method to Create Patterned Thin Films of Lithium Niobate for Hybrid Integrated Photonics
TS-062492 — Photonic integration is driven by demand for smaller size, lower cost, lower power consumption, easier assembly, higher reliability, and greater data density in modern photonic devices and systems. Among the many platforms, silicon photonics is particularly promising for photonic integration due t…
  • College: College of Engineering (COE)
  • Inventors: Reano, Ronald; Chen, Li
  • Licensing Officer: Zinn, Ryan

Enhanced anthocyanin-based colorants
TS-062228 — The Need The food industry is actively seeking alternatives to synthetic colorants due to consumer concerns over their safety and increasing legal challenges. Natural colorants, particularly anthocyanins found in fruits, vegetables, grains, and flowers, offer potential health benefits and a wide ra…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Giusti, M. Monica; Zhou, Yucheng
  • Licensing Officer: Panic, Ana

Compounds to Enhance the Quality and Taste of Coffee
TS-062218 — The Need The demand for higher quality coffee to meet the discerning tastes of consumers has always been a key driver for success. Innovative compounds and compositions that directly modulate the flavor of coffee products can enhance taste and quality but can be difficult to identify. The Tech…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Peterson, Devin; Gao, Chengyu
  • Licensing Officer: Panic, Ana

A liposomal subunit flu vaccine formulation
TS-062211 — The Need: Addressing the Limitations of Current Flu Vaccines Influenza epidemics and pandemics present significant challenges to public health and global economies. Existing flu vaccines are strain-specific, providing limited cross-protective immunity and often lack long-term effectiveness. Additio…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Gourapura, Renukaradhya; Carson, Kennith; Cheng, Xingguo; Dhakal, Santosh; Lee, Chang Won; McDonough, Joseph
  • Licensing Officer: Panic, Ana

Rare Earth Element Trap-Extract-Precipitate (REE-TEP) Process
TS-061849 — The Rare Earth Element Trap-Extract-Precipitate (REE-TEP) process is a cost-effective and environmentally benign approach to recover rare earth elements (REEs) from acidic waste streams. It involves beneficial reuse of readily available industrial by-products and a naturally occurring organic ligand resulting in REE concentrate that can be commercially processed to produce rare earth oxides (REOs).
The Need Rare earth elements are critical components of many emerging technologies. Because conventional sources of REEs in the United States are limited, identifying alternative sources is important. Many mining and industrial waste streams have elevated concentrations of REEs and can be potential…
  • College: College of Engineering (COE)
  • Inventors: Cheng, Chin-Min "Jason"; Bielicki, Jeffrey "Jeff"; Butalia, Tarunjit; Lenhart, John
  • Licensing Officer: Randhawa, Davinder

AI-Enabled Retrosynthesis for Drug Development
TS-060092 — AI methods and systems for predicting reactants and their synthesis paths to support drug design and chemical synthesis.
A time-consuming and costly step in drug development is the identification of drug-like small molecules that display desired properties against a specific biomolecular target and then the synthesis of such molecules if they do not exist. Retrosynthesis is a procedure where such a desired molecule i…
  • College: College of Medicine (COM)
  • Inventors: Ning, Xia; Chen, Ziqi
  • Licensing Officer: Hampton, Andrew

A Wireless, pH Regeneratable, Chemical Species Electronic Bio-Sensor
TS-058251 — Diagnostic tools are key to medicine, research and diagnostics. The measurement of biomolecules and their absorption kinetics can facilitate a better understanding of drug intake, biological responses, or in the continuous monitoring of specimen. Current equipment requires centralized equipment, t…
  • College: College of Engineering (COE)
  • Inventors: Li, Jinghua; Chen, Shulin; Liu, Tzu Li
  • Licensing Officer: Ashouripashaki, Mandana

Rabbit Model for Duchenne Muscular Dystrophy
TS-058084 — A rabbit model has been created for Duchenne Muscular Dystrophy (DMD) that more closely resembles the effects experienced in humans while being more cost effective compared to larger animal models.
There has yet to be a DMD animal model that bridges the gap between cost effectiveness and scientific relevance. This new rabbit model does that. DMD is a lethal genetic disease characterized by progressive muscle weakness and muscle wasting. There are several animal models for DMD, includin…
  • College: College of Medicine (COM)
  • Inventors: Han, Renzhi
  • Licensing Officer: Schworer, Adam

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