Available Technologies
# of Displayed Technologies: 10 / 10
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Revolutionizing Pharmaceutical Synthesis: Advancements in Metal-Catalyzed Coupling Technology
TS-064824 — The Need
In the pharmaceutical industry, the synthesis of complex organic substrates is crucial for the development of life-saving medications. However, traditional metal-catalyzed coupling reactions often face significant challenges when applied to these complex substrates, leading to high failure…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Dinh, Long; Hamby, Taylor; Starbuck, Hunter
- Licensing Officer: Willson, Christopher
Column-free Purification of Recombinant Proteins
TS-064270 — Large-scale recombinant proteins in Gram-negative bacteria (i.e., E. coli) are of significant interest in recombinant protein/enzyme production. These proteins exhibit wide-ranging applications, including food and beverages, conversion of carbohydrates into fuel ethanol or biodiesel, components for …
- College: College of Arts & Sciences
- Inventors: Gopalan, Venkat
- Licensing Officer: Willson, Christopher
Method and device for determining virus titer by surface enhanced Raman scattering
TS-062346 —
The ability to rapidly identify and determine virus titer is of utmost importance in numerous biomedical applications, ranging from gene editing to pharmaceutical and vaccine development. In the context of lentiviruses, which are widely used for cell reprogramming in immunotherapies, knowing the e…
- College: College of Arts & Sciences
- Inventors: Schultz, Zachary; Morder, Courtney
- Licensing Officer: Willson, Christopher
Dual ligand systems for cross-coupling of challenging C(sp2) and C(sp3) electrophiles.
TS-059018 — An unusual series of ligand exchange reactions establishes a dualcatalyst system for electroreductive alkyl-aryl cross-electrophile couplings of previously incompatible substrate combinations.
Cross-electrophile coupling (XEC) reactions of aryl and alkyl electrophiles are desirable methodologies for C–C bond formation but are limited to specific substrate classes. Couplings of widely-available electrophiles such as aryl chlorides or triflates are currently unknown with any alkyl b…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Hamby, Taylor
- Licensing Officer: Willson, Christopher
Transition Metal Free Alkyne Hydrogenation and Semihydrogenation Catalysts
TS-058577 — Novel, transition metal-free catalysts capable of alkyne hydrogenation and semihydrogenation under modest conditions.
The Need
Numerous industrial processes require alkyne semihydrogenation or hydrogenation reactions. For example, hydrogenation is necessary for the industrial-scale synthesis vitamin A, the creation of high molecular weight polymers, and the processing of petroleum into functionally useful derivati…
- College: College of Arts & Sciences
- Inventors: Goldberger, Joshua; Hodge, Kelsey
- Licensing Officer: Willson, Christopher
Transition Metal Free Alkyne Hydrogenation and Semihydrogenation Catalysts
TS-048726 — Novel, transition metal-free catalysts capable of alkyne hydrogenation and semihydrogenation under modest conditions.
The Need
Numerous industrial processes require alkyne semihydrogenation or hydrogenation reactions. For example, hydrogenation is necessary for the industrial-scale synthesis vitamin A, the creation of high molecular weight polymers, and the processing of petroleum into functionally useful derivati…
- College: College of Arts & Sciences
- Inventors: Goldberger, Joshua; Hodge, Kelsey
- Licensing Officer: Willson, Christopher
Development of a Single Component Methacrylate Adhesive Formulation
TS-042066 — A novel hybrid adhesive that combines the non-toxic, high strength properties of methacrylate adhesives with the bonding characteristics of polyurethanes
Despite the utility of methacrylate adhesive chemistry, applications have been limited to industrial and biomedical use cases. This is due to the curing mechanism, which is initiated by either heat, light or a two-component redox system. This invention describes two strategies to create a single-c…
- College: College of Arts & Sciences
- Inventors: Parquette, Jonathan; Schricker, Scott
- Licensing Officer: Dahlman, Jason "Jay"
Method for Connectorizing Superconducting NbTi Coaxial Cables
TS-040418 — A fast and inexpensive electroplating technique for producing a connector attachment matching the structural and electrical properties of standard coaxial cables for cryogenic applications.
Experiments performed at cryogenic temperatures much below the 4.2 K of liquid helium frequently require superconducting coaxial cables to efficiently transmit high frequency signals while minimizing heat transfer to the experiment’s cold stage. These cables are most often made of niobium-ti…
- College: College of Arts & Sciences
- Inventors: DeBry, Kyle; Lafyatis, Gregory
- Licensing Officer: Dahlman, Jason "Jay"
Development of Non-Foaming High Strength, Single Component Methacrylate/Polyurethane Adhesive
TS-037956 — A single component, moisture-cured methacrylate/polyurethane hybrid adhesive that combines the non-toxic, high strength properties of methacrylate adhesives with the bonding characteristics of polyurethanes
Methacrylate adhesives are strong and can be used on similar or dissimilar materials, such as plastic, metal, composites, and ceramic. They have excellent peel strength, resist abrasion, and stand up to a fair range of temperatures. They also require little preparation of the surfaces to be bonded…
- College: College of Arts & Sciences
- Inventors: Parquette, Jonathan; Bewick, Nicholas; Schricker, Scott
- Licensing Officer: Sita, Cordellia
High Surface Area Catalysts for Fuel Cells
TS-014755 — A high performance and durable reductive catalyst for polymer and metal-air fuel cells
Fuel cells offer a cleaner, more-efficient alternative to gasoline and other fossil fuels, and have the potential to revolutionize the way the nation is powered. Fuel cells operate in a similar fashion to conventional batteries, but fuel cells can be continually supplied with a fresh feed of fuel,…
- College: College of Arts & Sciences
- Inventors: Co, Anne; Coleman, Eric
- Licensing Officer: Randhawa, Davinder
