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Integrated Biomanufacturing System for Fiber-Reinforced Tissue Composites
TS-047830 — An automated technique and system which combines electrospinning, additive manufacturing, and cell dispensing for generating high-quality tissue constructs with high physiological relevance.
Recent advances in biofabrication introduced by additive manufacturing/3D printing (AM/3DP) have significantly improved the overall architecture control in tissue engineered constructs. These constructs have a wide variety of important research and clinical applications including, but not limited …
  • College: College of Engineering (COE)
  • Inventors: Zhang, Xu; Herderick, Edward; Niu, Ye "Ye"; Zhao, Yi
  • Licensing Officer: Zinn, Ryan

Gas Sensors for Health Monitoring and Diagnostics
TS-047136 — A range of low-cost gas sensors for non-invasive diagnostic tests and health monitoring.
Exhaled human breath is a combination of hundreds of gases including inorganic molecules such as NO, NH3 or CO, and volatile organic molecules such as acetone, ethane, and isoprene. Some of these gases are produced by the body as the result of physiological processes. Known as ‘biomarkers&rs…
  • College: College of Engineering (COE)
  • Inventors: Gouma, Pelagia-Iren
  • Licensing Officer: Gooray, Arthur "Art"

ReScribe: Transcription factors for reprogramming of diseased musculoskeletal related cells
TS-046978 — Transcription factors that can upregulate desired genes in diseased tissue to reprogram diseased cells, thereby reversing the disease and creating healthy non-diseased phenotype genes. These transcription factors would be especially useful in musculoskeletal diseases such as back pain and osteoarthritis.
Musculoskeletal diseases including osteoarthritis and chronic low back pain, are debilitating, painful, and often difficult to treat. Intervertebral disc (IVD) degeneration, as an example, is strongly associated with low back pain, a leading cause of disability worldwide. According to the American…
  • College: College of Engineering (COE)
  • Inventors: Walter, Devina; Gallego Perez, Daniel; Higuita Castro, Natalia; Hoyland, Judith; Khan, Safdar; Tang, Shirley "Shirley Nina"; Walter, Benjamin
  • Licensing Officer: Aanstoos, Megan

Folding Transducer Array for Compact and Deployable Wave-Energy Guiding System
TS-043186 — A novel acoustic/ultrasonic wave-energy guiding system that utilizes structural topology to enhance directional and spectral sensitivities instead of phase delay, offering exceptional versatility and adaptable performance.
Although acoustic beamforming systems that are based on phase delays can be used to enhance directional and spectral sensitivities, each source or receiver must be individually controlled by appropriate phase delays to guide the acoustic energy radiation/reception sensitivities. This results in a …
  • College: College of Engineering (COE)
  • Inventors: Harne, Ryan
  • Licensing Officer: Norris, Francis "Frank"

Nanopump Separation Device and Method
TS-037584 — A device for separating macromolecules in a solution of macromolecules having different molecular sizes
Many clinical and research applications involve separation of specific biological molecules, such as nucleic acids and proteins, for further analysis and characterization. A complex biological system can only be understood after each component has been separately analyzed, and proteins must be pur…
  • College: College of Engineering (COE)
  • Inventors: Hansford, Derek; Walczak, Robbie
  • Licensing Officer: Ezzell, Janel

A Wearable Integrated System of Augmented Reality for Targeted Pathologic Specimen Sampling
TS-037535 — An integrated system to improve the quality of analysis of the resected tumor specimen that provides the pathologist with the latest technological and scientific advancements.
In the field of cancer pathology, the identification and sampling of tumors is essential for both surgical applications and treatment plans for patients that may include post-operative chemotherapy and/or radiation therapy. Currently pathologists and pathologist assistants rely on visual and tacti…
  • College: College of Engineering (COE)
  • Inventors: Yilmaz, Alper; Hall, Nathan; Hitchcock, Charles; Lee, Young Jin; Martin, Edward; Nichols, Shawnn; Ozer, Enver; Povoski, Stephen; Sachire, Jennifer; Xu, Ronald
  • Licensing Officer: Norris, Francis "Frank"

Time Management Facilitator
TS-037366 — A novel device to reinforce the abstract concept of time to intellectually disabled children, especially those with Down syndrome.
Learning and understanding the abstract and intangible concept of time is especially difficult for children with Down Syndrome. This difficulty can cause deep frustration because it affects the family’s daily routine and reduces the child’s independence in the home, at school, and even…
  • College: College of Engineering (COE)
  • Inventors: Rogers, Peter "Peter"; Alley, Krista; Cornelius, Kristen; Dew, Elise; Hegedus, Alexander; Johnson, Kyle; Shiroma, Cecilia; Weisbecker, Carolyn; Whitehouse, Katherine
  • Licensing Officer: Aanstoos, Megan

Joint Stability Measurement Device for Total Knee Arthroplasty
TS-015289 — A device to intra-operatively measure varus/valgus, internal/external, and anterior/posterior stability for total knee arthroplasty
Total knee arthroplasty (TKA) is performed to relieve pain and disability associated with degenerative joint disease. Joint instability remains a leading cause of revision surgery following TKA. During the surgery, indicators of stability such as joint space are used to balance the knee. Many devi…
  • College: College of Engineering (COE)
  • Inventors: Siston, Robert; Maack, Thomas; Maack, Horst; Van Gorp, Cornel
  • Licensing Officer: Aanstoos, Megan

Non-Invasive Electromagnetic Method for Continuous Detection and Monitoring of Malaria
TS-015267 — An inexpensive device that utilizes non-invasive electromagnetic interactions with red blood cells to provide continuous monitoring for or diagnosis of malaria.
Plasmodium falciparum (PF), a form of malaria, is the deadliest and most prevalent parasite in humans due to its pervasiveness in temperate areas of the underdeveloped world. In 2013, there were nearly 198 million cases of malaria and an estimated 584,000 deaths, mostly among African children (BCC…
  • College: College of Engineering (COE)
  • Inventors: Subramaniam, Vishwanath; Drew, Mark; Smith, Brad; West, Joseph
  • Licensing Officer: Paschall, Christopher

SmartHub Wheelchair Fitness Tracker
TS-015141 — The SmartHub is a personal fitness and activity tracking device designed for manual wheelchair users.
Fitness tracking technology has boomed in recent years. However, none of the technology that has been sold has been useable by those in wheelchairs. Either these devices rely on total body movement or the algorithms are not adapted for movement in a wheelchair instead of by walking upright. Many p…
  • College: College of Engineering (COE)
  • Inventors: Metzler, Sandra; DiGiovine, Carmen; Eakins, Kyle; Mubaslat, Jad; Nishio, Lee; Shaffer, Sarah
  • Licensing Officer: Hong, Dongsung

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