# of Displayed Technologies: 5 / 5

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Functionalization of Polymethylmethacrylate (PMMA) Surface by Amination with Polyethyleneimine (PEI) for Applications in Microfluidic Immunoassays, Protein/Enzyme Biochips, and Biocatalysis
TS-037631 — Polymethylmethacrylate (PMMA) is a useful material for development of assays, biochips, and other biological materials. However, PMMA makes for a difficult substrate because of complexities with respect to adhesion. This technology presents two new methods for enhanced protein binding onto PMMA.
Polymethylmethacrylate (PMMA) is a synthetic resin in the acrylic family, often used as a substitute for glass or as a material for biomedical devices. PMMA-based biosensors have low protein binding efficiency and low sensitivity. PMMA is used in a variety of applications like immunoassays, biosen…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Bai, Yunling
  • Licensing Officer: Davis, Stewart

Nanopump Separation Device and Method
TS-037584 — A device for separating macromolecules in a solution of macromolecules having different molecular sizes
Many clinical and research applications involve separation of specific biological molecules, such as nucleic acids and proteins, for further analysis and characterization. A complex biological system can only be understood after each component has been separately analyzed, and proteins must be pur…
  • College: College of Engineering (COE)
  • Inventors: Hansford, Derek; Walczak, Robbie
  • Licensing Officer: Ezzell, Janel

A Wearable Integrated System of Augmented Reality for Targeted Pathologic Specimen Sampling
TS-037535 — An integrated system to improve the quality of analysis of the resected tumor specimen that provides the pathologist with the latest technological and scientific advancements.
In the field of cancer pathology, the identification and sampling of tumors is essential for both surgical applications and treatment plans for patients that may include post-operative chemotherapy and/or radiation therapy. Currently pathologists and pathologist assistants rely on visual and tacti…
  • College: College of Engineering (COE)
  • Inventors: Yilmaz, Alper; Hall, Nathan; Hitchcock, Charles; Lee, Young Jin; Martin, Edward; Nichols, Shawnn; Ozer, Enver; Povoski, Stephen; Sachire, Jennifer; Xu, Ronald
  • Licensing Officer: Norris, Francis "Frank"

Tethered Liposomal Nanoparticle (tLN) Microarray Chips Containing Molecular Probes for Simultaneous Cell Sorting and Bio Detection
TS-037347 — A simple, and efficient method for identifying intra-cellular biomarkers for the targeted treatment of disease.
Tethered Lipoplex Nanoparticle (TLN) microarray biochips simultaneously capture and identify extracellular vesicles (EV) RNA targets from human plasma or bodily fluids with or without EV isolation. Molecular detection probes, such as molecular beacons (MBs), identify specific micro RNA (miRNA) or …
  • College: College of Engineering (COE)
  • Inventors: Lee, L James; Kwak, Kwang Joo; Lee, Andrew; Wu, Yun; Yu, Bo
  • Licensing Officer: Norris, Francis "Frank"

Multichannel Polymer Chips for Rapid Multiplex Enzyme-Linked Immunosorbent Assay
TS-014978 — A more accurate, cost efficient and faster method to one of the most widely used diagnostic tests in the world.
The conventional Enzyme-Linked Immunosorbent Assay, or ELISA, is typically carried out in a 96-well or 384-well microliter plate. The method involves a series of mixing and washing steps, which are not only tedious and laborious, but which also often result in large errors and inconsistent outcome…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Bai, Yunling; Huang, Wei-Cho
  • Licensing Officer: Davis, Stewart

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