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Novel selective protein purification via tangential flow filtration
TS-046780 — Dr. Andre Palmer’s lab at The Ohio State University has developed a novel purification method to isolate any target protein from a complex mixture. The process purifies a target protein (TP) from a mixture by exploiting molecular size changes that result from the formation of a protein complex consisting of a TP and its TP binding molecule (TPBM). This is accomplished via Tangential Flow Filtration (TFF). This process allows for simple and scalable purification of any protein, providing a wide range of applicability.
Proteins can be used in various medical and research applications including drug delivery, hemolysis therapies, and cancer therapies. However, purification of proteins from complex mixtures can require extensive process development. Current methods for protein purification rely on column chromatog…
  • College: College of Engineering (COE)
  • Inventors: Susin Pires, Ivan; Palmer, Andre
  • Licensing Officer: Davis, Stewart

N-Proanol and Propionic Acid Producing Propionibacteria
TS-037515 — New method of producing n-propanol and propionic acid using a metabolically engineered propionibacteria.
Propionibacteria are well-known for their various industrial applications including the manufacturing of Swiss cheese, vitamin B12, and propionic acid. However, not much is known about their genetics, and few studies have been conducted utilizing them for metabolic engineering, mostly in vitamin B…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Ammar, Ehab
  • Licensing Officer: Willson, Christopher

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