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Mouse Hybridoma BC25B11.2C Secreting Monoclonal Antibodies to Bovine Coronavirus
TS-037408 — A cloned mouse hybridoma cell line with potential use in diagnosis and treatment of bovine coronavirus (DB2 strain).
Bovine Coronavirus (BCV) - DB2 strain causes high death losses in young calves. Monoclonal antibodies produced in mice injected with hybridoma cells or concentrated hybridoma supernatant produced against bovine coronavirus- DB2 strain can be used to improve diagnostic tests, for possible therapy i…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Saif, Linda
  • Licensing Officer: Dahlman, Jason "Jay"

Immortalized Duck Embryonic Intestinal Epithelial Cell line (MK-DIEC)
TS-036842 — An immortalized duck embryonic intestinal epithelial cell line (MK-DIEC) for producing live and killed vaccines
Currently most vaccine production is done through live embryonic eggs or primary cell cultures, allowing researchers to replicate pathogen function. Although existing vaccines for influenza and animal intestinal diseases such as porcine epidemic diarrhea virus (PEDV) exist and are considered effec…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Khatri, Mahesh
  • Licensing Officer: Dahlman, Jason "Jay"

Swine liver stem/progenitor cell line
TS-036771 — A spontaneously immortalized swine liver stem/progenitor cell line developed from normal White-Duroc crossbred pigs.
World-wide vaccine production is a multi-billion dollar industry. Currently, most vaccines are produced in live embryonated eggs or primary cell cultures. Vaccine production from eggs has been around for over half a century and can be costly and slow. Swine vaccine production from cell lines is of
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Khatri, Mahesh; Saif, Yehia
  • Licensing Officer: Dahlman, Jason "Jay"

Method for isolation of anthocyanin-mixtures from plant materials.
TS-036614 — A mixed-mode method for the isolation of anthocyanin-mixtures from plant materials.
Many biological studies currently rely on the extraction and fractionation of high purity pigments known as anthocyanins from fruits and vegetables, due to their ability to provide color and potential for increased health benefits. As a result of these benefits, anthocyanins have many applications…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Giusti, M. Monica "Monica"; Simmons, Steven
  • Licensing Officer: Flammang, Ann Marie

Automating the quantification of color space parameters from Visible Spectrum Absorbance
TS-036603 — Verbal communication of color is challenging, therefore mathematically-standardized color spaces are used. ColorBySpectra is software that in one click can convert large sets of absorbance data obtained from a simple spectrophotometer into color spaces: Hunter Lab, CIEL*c*h* and CIEL*a*b*. It reduces time for data collection, and sample volume and equipment needs. The software is useable on multiple platforms and would be useful in food science or other industries interested in precise color information.
There are several commonly used color spaces that quantify perceived color which include Hunter Lab, CIELab, and CIELch. To obtain these values, samples are usually presented to a colorimeter one sample at a time. Obtaining color data can be time consuming for many samples, and special equipment d…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Farr, Jacob; Giusti, M. Monica "Monica"
  • Licensing Officer: Flammang, Ann Marie

Immortalized Porcine Bone Marrow Mesenchymal Stromal Cell Line
TS-033666 — The cell line serves as a useful tool for examining mechanisms of tissue repair and supports the replication of newly identified porcine epidemics.
Porcine Epidemic Diarrhea Virus (PEDV) is a coronavirus that infects the cells lining the small intestine of a pig. PEDV has a substantial economic burden. It is highly infectious, and it is deadly to baby pigs from birth until about three weeks of age. Infected swine herds can suffer a 75-100% lo…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Khatri, Mahesh
  • Licensing Officer: Dahlman, Jason "Jay"

Bioluminescent Clavibacter Michiganensis
TS-015169 — Bioluminescent Clavibacter michiganensis subspecies michiganensis (Cmm) strains are used as a tool for monitoring and developing disease control products for tomatoes
Currently, there are no tomato varieties that are resistant to Clavibacter michiganensis subspecies michiganensis (Cmm). Furthermore, Cmm-plant interactions are poorly understood. Developing an understanding of Cmm strains will allow growers to develop products that are highly active against this …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Miller, Sally; Rajashekara, Gireesh; Xu, Xiulan
  • Licensing Officer: Dahlman, Jason "Jay"

Anthocyanin Purification Method
TS-014932 — A highly pure and efficient method for anthocyanin purification from fruits and vegetables
Anthocyanins are natural pigments responsible for the vivid red to blue colors of many fruits and vegetables. As highly consumed dietary antioxidants, anthocyanins are receiving increasing attention due to their potential health benefits. Growing evidence from epidemiological, cell culture, animal…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: He, Jian; Giusti, M. Monica "Monica"
  • Licensing Officer: Flammang, Ann Marie
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