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Isolation of Porcine Epidemic Diarrhea Virus (PEDV) strain Iowa106
TS-044567 — Porcine epidemic diarrhea virus (PEDV) appeared in the US in 2013 and has spread rapidly throughout North America. The virus causes gastroenteric disease in adults and is fatal to nursing piglets, whose only protection from the disease is via passive immunity from their mother. Currently, most US …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Wang, Qiuhong; Oka, Tomoichiro; Saif, Linda
  • Licensing Officer: Dahlman, Jason "Jay"

Small molecule modulators of Avian Pathogenic E. coli (APEC) virulence as a means to control avian collibacillosis
TS-040540 — Small molecules have been developed that have shown effective defense against Avian pathogenic Escherichia coli (APEC). These molecules can be used by itself, or with current antibiotics, which helps decrease the overall risk of bacterial antibiotic resistance.
Avian pathogenic Escherichia coli (APEC) is one of the most common poultry diseases that is characterized by a series of extra intestinal infections that effect the visceral organs of the bird. The disease affects chickens, turkeys, and other avian species, and highly reduces egg production and we…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Deblais, Loic; Kathayat, Dipak; Mohamed, Yosra
  • Licensing Officer: Dahlman, Jason "Jay"

Small molecule growth inhibitors of avian pathogenic E. coli (APEC) as a means to control APEC infections in poultry.
TS-039568 — Small molecules have been developed that have shown effective defense against Avian pathogenic Escherichia coli (APEC). These molecules can be used by itself, or with current antibiotics, which helps decrease the overall risk of bacterial antibiotic resistance.
Avian pathogenic Escherichia coli (APEC) is one of the most common poultry diseases that is characterized by a series of extra intestinal infections that effect the visceral organs of the bird. The disease affects chickens, turkeys, and other avian species, and highly reduces egg production and we…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Deblais, Loic; Kathayat, Dipak; Mohamed, Yosra
  • Licensing Officer: Dahlman, Jason "Jay"

Control of Salmonella in poultry using new generation small molecule growth inhibitors
TS-039567 — Small molecule compounds that can be used to inhibit Salmonella growth for safe and sustainable poultry production.
Non-typhoidal Salmonella are among the top five intestinal pathogens in the United States. Among foodborne illnesses, they are responsible for 11% of illnesses, 35% of those hospitalizations, and 28% deaths, with an estimated cost of $3.6 billion in 2014. Poultry is the most common source of wide-…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Deblais, Loic; Kathayat, Dipak; Miller, Sally; Mohamed, Yosra
  • Licensing Officer: Dahlman, Jason "Jay"

Mucoadhesive Nanoparticle Entrapped Influenza Virus Vaccine Delivery System
TS-038882 — A mucoadhesive nonoparticle entrapped influenza virus vaccine delivery system for animals and humans.
As one of the top three swine respiratory health problems in the U.S., swine influenza virus (SIV) is a key concern for the industry. SIV – referred to as “swine flu” or “flu” – can be caused by a number of different swine influenza strains. SIV has evolved from…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Gourapura, Renukaradhya; Dhakal, Santosh; Renu, Sankar
  • Licensing Officer: Dahlman, Jason "Jay"

Composition and oral delivery of nanoparticle based Salmonella vaccine for poultry
TS-038337 — A Salmonella oral vaccine to provide mucosal immunity and reduce bacterial shedding in poultry.
Fifteen of every 100,000 people will contract salmonellosis annually in the United States, with a related cost of $3.6 million in economic and medical expenses. A single outbreak can quickly increase these costs - Alamosa, CO paid over $2.6 million in 2008 following an outbreak. The disease comes …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Gourapura, Renukaradhya; Renu, Sankar; Selvaraj, Ramesh
  • Licensing Officer: Dahlman, Jason "Jay"

Probiotic strains for reducing antibiotic resistance and modulating poultry gut health
TS-037818 — A novel advancement in food animal production to mitigate antibiotic resistance in the ecosystem.
Antibiotic resistance is a major challenge to human health worldwide. The broad uses of antibiotic resistance is considered key the problem seen today. Targeted mitigation of all antibiotic resistant bacteria is essential to achieve effective control of the current problem and also protection of h…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Wang, Hua; wang, zihua; Zhang, Lu; Zhou, Yang
  • Licensing Officer: Dahlman, Jason "Jay"

Mouse hybridoma 25C9.3C Secreting Monoclonal Antibodies to Porcine Coronavirus
TS-037407 — A cloned mouse hybridoma cell line
Transmissible gastroenteritis coronavirus (TGEV) is a porcine virus that has a mortality rate close to 100% in young pigs. Monoclonal antibodies produced in mice injected with hybridoma cells or concentrated hybridoma supernatant produced against porcine coronavirus-TGEV can be used to improve dia…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Saif, Linda
  • Licensing Officer: Dahlman, Jason "Jay"

Cultivable Porcine Deltacoronavirus
TS-036864 — A cultivable porcine deltacoronavirus to act as a stepping stone for porcine deltacoronavirus vaccine development.
Currently, there is a lack of an effective vaccine to completely treat porcine deltacoronavirus (PDCoV), leaving many pigs vulnerable to the virus's adverse effects, including dehydration, diarrhea, and possible death. Thus, research and development methods and technologies that will improve s…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Saif, Linda; Hu, Hui
  • Licensing Officer: Dahlman, Jason "Jay"

Food-Safe, Naturally Produced Antimicrobials
TS-015129 — A new strain of Paenibacillus polymyxa, producing a stable extra-cellular metabolite, paenibacillin, that has strong antimicrobial activity against Gram-positive bacteria
The emergence of bacterial antibiotic resistance has mobilized the search for new potent antimicrobial agents. Although much of the resistance was observed in hospital environments and related nosocomial infections, there is increasing evidence that resistant food-borne pathogens evolved due to an…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Yousef, Ahmed; He, Zengguo; Kisla, Duygu
  • Licensing Officer: Flammang, Ann Marie

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