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Self-assembled 3D RNA Cage Nanoparticles with Precise Shape and Size for Applications in Medical Sciences, Materials Sciences, Engineering and Nanotechnology
TS-039545 — Self-assembling, highly stable RNA cages amenable to custom functionalization and cargo delivery
One of the primary challenges in therapeutic development is cheap, efficient, and safe drug delivery to specific target tissues. To better target specific tissues, RNA nanotechnology has been progressively applied to generate predefined architectures via self-assembly of modular building blocks. N…
  • College: College of Pharmacy
  • Inventors: Guo, Peixuan; Jasinski, Daniel; Khisamutdinov, Emil; Li, Hui
  • Licensing Officer: Flammang, Ann Marie

Dietary Carotenoid Assessment Tool (DCAT).
TS-038892 — A screening tool for rapid estimation of dietary carotenoid intake
The Need Diet is a major variable that contributes to human health and disease risk. Decades of scientific research suggest that dietary patterns rich in a variety of fruit and vegetables can reduce the risk of cancer through numerous mechanisms, however accurate dietary assessment remains challeng…
  • College: College of Medicine (COM)
  • Inventors: Clinton, Steven; Grainger, Elizabeth; Schmitz, Ashley; Simpson, Christina "Christi"; Thomas-Ahner, Jennifer
  • Licensing Officer: Flammang, Ann Marie

Method for isolation of anthocyanin-mixtures from plant materials.
TS-036614 — A mixed-mode method for the isolation of anthocyanin-mixtures from plant materials.
Many biological studies currently rely on the extraction and fractionation of high purity pigments known as anthocyanins from fruits and vegetables, due to their ability to provide color and potential for increased health benefits. As a result of these benefits, anthocyanins have many applications…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Giusti, M. Monica "Monica"; Simmons, Steven
  • Licensing Officer: Flammang, Ann Marie

Automating the quantification of color space parameters from Visible Spectrum Absorbance
TS-036603 — Verbal communication of color is challenging, therefore mathematically-standardized color spaces are used. ColorBySpectra is software that in one click can convert large sets of absorbance data obtained from a simple spectrophotometer into color spaces: Hunter Lab, CIEL*c*h* and CIEL*a*b*. It reduces time for data collection, and sample volume and equipment needs. The software is useable on multiple platforms and would be useful in food science or other industries interested in precise color information.
There are several commonly used color spaces that quantify perceived color which include Hunter Lab, CIELab, and CIELch. To obtain these values, samples are usually presented to a colorimeter one sample at a time. Obtaining color data can be time consuming for many samples, and special equipment d…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Farr, Jacob; Giusti, M. Monica "Monica"
  • Licensing Officer: Flammang, Ann Marie

Rapidly reversible DNA-quadruplex-based molecular capture system
TS-015081 — A specific and rapidly reversible system for single molecule capture employing magnesium-dependent DNA quadruplex structures.
Research and medical technology are increasingly dependent on single molecule capture and analysis. The current gold standard for non-covalent immobilization is streptavidin-biotin (STV-B). Although widely used, the biotin component in the interaction is resistant to dissociation, thus requiring h…
  • College: College of Arts & Sciences
  • Inventors: Kankia, Besik
  • Licensing Officer: Flammang, Ann Marie

Anthocyanin Purification Method
TS-014932 — A highly pure and efficient method for anthocyanin purification from fruits and vegetables
Anthocyanins are natural pigments responsible for the vivid red to blue colors of many fruits and vegetables. As highly consumed dietary antioxidants, anthocyanins are receiving increasing attention due to their potential health benefits. Growing evidence from epidemiological, cell culture, animal…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: He, Jian; Giusti, M. Monica "Monica"
  • Licensing Officer: Flammang, Ann Marie
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