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Multifunctional RNA Nanoparticles and Methods for Treating Cancer
TS-040289 — Three-way junction nanoparticles for delivery of tamoxifen and other therapeutics directly to tumor cells.
Most breast cancers express estrogen receptor alpha (ER α) and antagonists of ER α drugs, such as tamoxifen, have been widely used for their treatment. Unfortunately, up to half of all ER α -positive tumors have intrinsic or acquired endocrine therapy resistance. Recent studies b…
  • College: College of Pharmacy
  • Inventors: Zhang, Xiaoting; Guo, Peixuan
  • Licensing Officer: Flammang, Ann Marie

Quadruplex-Based Technology for Mono-Adapter DNA Library Preparation and Isothermal Clone Generation for Next Generation Sequencing (NGS)
TS-037745 — A technique for the isothermal amplification of DNA libraries for a more efficient and robust sequencing method.
Identification of a particular nucleic acid is desirable in the use of diagnostic and forensic applications. However, often the target nucleic acid sequence may only be a small portion of the DNA or RNA in question so that amplification is needed before sufficient quantities are available for iden…
  • College: College of Arts & Sciences
  • Inventors: Kankia, Besik
  • Licensing Officer: Flammang, Ann Marie
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