# of Displayed Technologies: 16 / 16


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Thermotropic liquid crystal-based sensors for naked-eye detection of SARS-CoV-2 with ultrahigh sensitivity and selectivity
TS-063069 — In the wake of the global pandemic caused by SARS-CoV-2, the need for rapid, accurate, and efficient diagnostic methods for respiratory viral infections has become more critical than ever. Traditional diagnostic methods, while reliable, are often time-consuming, labor-intensive, and lack the neces…
  • College: College of Engineering (COE)
  • Inventors: Wang, Xiaoguang; Qin, Rongjun; Rather, Adil; Xu, Yang
  • Licensing Officer: Randhawa, Davinder

Novel Efficient Butanol Production without CO2 Emission
TS-062607 — Chemicals and fuels from renewable resources have gained global interest due to environmental issues, climate change, oil price and supply volatility, and decreasing nonrenewable fossil fuel sources. Butanol is a biofuel alternative that can provide a higher heating value, lower volatility, polarity…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"
  • Licensing Officer: Panic, Ana

Advanced Biopesticides and Bio Stimulants for Sustainable Crop Protection and Growth Enhancement
TS-062409 — The Need: In the face of climate change and the diminishing efficacy of conventional pest control methods, the agricultural industry is in dire need of sustainable solutions to protect and enhance crop growth. The escalating disease pressure calls for innovative technologies that can bolster a plant…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Wang, Guo-Liang; Bhat, Prabhat; Pei, Dehua; Wang, Jiyang
  • Licensing Officer: Dahlman, Jason "Jay"

Propionibacterium acidipropionici Knockout Mutant for Propionic Acid Fermentation
TS-062323 — The Need: In today's industrial landscape, the demand for sustainable and cost-effective bio-based chemicals continues to rise. Propionic acid, a valuable building block in various industries, including food, pharmaceuticals, and plastics, is no exception. However, conventional production method…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"
  • Licensing Officer: Panic, Ana

Probiotic strains for reducing antibiotic resistance and modulating gut health
TS-037818 — A novel advancement to mitigate antibiotic resistance in the ecosystem.
The Need In today's world, the rapid emergence of antibiotic resistance (AR) poses a serious threat to public health, making it crucial to explore alternative strategies to combat this issue. Traditional approaches targeting pathogenic bacteria alone have proven insufficient due to the complexi…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Wang, Hua; Wang, Zihua; Zhang, Lu; Zhou, Yang
  • Licensing Officer: Dahlman, Jason "Jay"

Production of Galacto-oligosaccharides from Lactose by Enzyme Immobilized on Cotton Cloth
TS-037689 — Lactose from cheese whey is converted from a dairy byproduct to a useful prebiotic using enzymes immobilized on cotton cloth.
Galacto-oligosaccharides (GOS) are a collection of prebiotic fibers made of a chain of galactose sugars of variable length. GOS has been shown to exert some of the most potent and beneficial effects among prebiotic fibers. When added to infant formula, it can change bowel flora to approximate the …
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Albayrak, Nedim
  • Licensing Officer: Panic, Ana

Methods for Making Three Dimensional Microfluidic Bioreactor Array
TS-037642 — Design for a three-dimensional microfluidic bioreactor array; device allows for culturing of a variety of cell types without contamination.
Cell culture in a three-dimensional fluidic-flow microenvironment is critical for long-term cell-based assays. Conducting in vitro research offers an accessible, reproducible, and reliable mode of investigation for therapeutic decisions before work is conducted in vivo. However, because of the com…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Wen, Yuan
  • Licensing Officer: Panic, Ana

Functionalization of Polymethylmethacrylate (PMMA) Surface by Amination with Polyethyleneimine (PEI) for Applications in Microfluidic Immunoassays, Protein/Enzyme Biochips, and Biocatalysis
TS-037631 — Polymethylmethacrylate (PMMA) is a useful material for development of assays, biochips, and other biological materials. However, PMMA makes for a difficult substrate because of complexities with respect to adhesion. This technology presents two new methods for enhanced protein binding onto PMMA.
Polymethylmethacrylate (PMMA) is a synthetic resin in the acrylic family, often used as a substitute for glass or as a material for biomedical devices. PMMA-based biosensors have low protein binding efficiency and low sensitivity. PMMA is used in a variety of applications like immunoassays, biosen…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Bai, Yunling
  • Licensing Officer: Panic, Ana

Methods and Processes for Producing Butyrate Esters from Sugars
TS-037568 — A method and process for producing butyrate esters for use as novel biofuels.These products have a similar energy content to biobutanol, but are easier to produce.
Currently, bioethanol is the major biofuel on the market, but recently butanol has gotten attention for its potential as a transportation fuel. It has many characteristics that make it a better fuel source than ethanol: butanol has 25% more Btu per gallon, it's less evaporative/explosive with …
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"
  • Licensing Officer: Panic, Ana

Metabolic Engineering of Clostridium Tyrobutyricum for Butanol Production
TS-037555 — A new strain of bacteria that can produce butanol at a high titer for transportation fuel.
Butanol is generally used as an industrial solvent but can also be blended with gasoline and used as transportation fuel. Butanol is commonly produced using fossil fuels, but it can also be produced from biomass, referred to as biobutanol. Biobutanol is produced from fermentation of the same feeds…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Yu, Mingrui
  • Licensing Officer: Panic, Ana

N-Proanol and Propionic Acid Producing Propionibacteria
TS-037515 — New method of producing n-propanol and propionic acid using a metabolically engineered propionibacteria.
Propionibacteria are well-known for their various industrial applications including the manufacturing of Swiss cheese, vitamin B12, and propionic acid. However, not much is known about their genetics, and few studies have been conducted utilizing them for metabolic engineering, mostly in vitamin B…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Ammar, Ehab
  • Licensing Officer: Panic, Ana

CO2 Reduction to Acetate on Mixed Metal Oxide Catalyst
TS-037385 — A process for photoelectrochemical reduction of carbon dioxide to acetate using mixed metal oxide as catalysts
The combustion of fossil fuels produces billions of tons of carbon dioxide annually. Research indicates that greater concentrations of carbon dioxide in the atmosphere has altered Earth's climate, changed the pH of the ocean, and causing other potentially damaging evironmental effects. Countri…
  • College: College of Arts & Sciences
  • Inventors: Baker, Lawrence "Robert"; Yang, Xin
  • Licensing Officer: Panic, Ana

Amine-Containing Membranes Incorporated with Carbon Nanotubes or CO2 Separation
TS-037297 — A novel amine-containing membrane incorporated with carbon nanotubes for CO2/N2 separation with a vacuum pulled on the permeate side
CO2 concentration in the atmosphere has surpassed 400 ppm in the past decade. The combustion of fossil fuels is a major contributor to the large amount of CO2 emission, and membrane technologies have been suggested as a promising approach to capture CO2 from large stationary sources (e.g., flue ga…
  • College: College of Engineering (COE)
  • Inventors: Ho, W.S. Winston; Han, Yang
  • Licensing Officer: Ashouripashaki, Mandana

Multichannel Polymer Chips for Rapid Multiplex Enzyme-Linked Immunosorbent Assay
TS-014978 — A more accurate, cost efficient and faster method to one of the most widely used diagnostic tests in the world.
The conventional Enzyme-Linked Immunosorbent Assay, or ELISA, is typically carried out in a 96-well or 384-well microliter plate. The method involves a series of mixing and washing steps, which are not only tedious and laborious, but which also often result in large errors and inconsistent outcome…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Bai, Yunling; Huang, Wei-Cho
  • Licensing Officer: Panic, Ana

Small Molecule AR-Ablative Agents
TS-014842 — A new strategy for using androgen receptor ablative agents has been developed for prostate cancer therapy.
Hormone-refractory prostate cancer is incurable, and patients with this disease have few treatment options. Dysregulation of the androgen receptor (AR) is a hallmark of this incurable cancer. Molecular changes during cancer enhance AR sensitivity or permit AR activation by antiestrogen so that pro…
  • College: College of Pharmacy
  • Inventors: Chen, Ching-Shih; Wang, Dasheng; Yang, Jian
  • Licensing Officer: Taysavang, Panya

Butanol Production from Renewable Biomass
TS-014747 — A genetically engineered bacteria pathway directed to selectively generate butanol over competing by-products.
Acetone-Butanol-Ethanol (ABE) Fermentation is one of two methods to produce butanol from biomass feedstocks. Various active enzymes or acids are exposed to a biomass feedstock and subsequently produce primarily acetone, butanol and ethanol. Previous attempts in the industry to use Clostridium stra…
  • College: College of Arts & Sciences
  • Inventors: Yang, Shang-Tian "ST"; Zhao, Jingbo
  • Licensing Officer: Panic, Ana

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