Available Technologies
# of Displayed Technologies: 4 / 4
Novel Immunomodulators and Vaccine Adjuvants
TS-038032 — A class of compounds possessing potent immunomodulatory activity, to enhance the protection of vaccines against infectious agents.
While vaccines are commonly used today for a variety of diseases and have proven efficacious for disease prevention, some vaccines do not efficiently activate an immune response. About 10% of vaccinations fail to mount adequate antibody levels to routine vaccinations. Also, many viruses rapidly mu…
- College: College of Medicine (COM)
- Inventors: Satoskar, Abhay; Ainslie, Kristy; Bachelder, Eric; Fuchs, James; Kinghorn, Alan "Dr. A. Douglas Kinghorn"; Parinandi, Narasimham
- Licensing Officer: Schultz, Teri
Phyllanthusmin and acutissimalignan A compound derivatives for anticancer and immunostimulation
TS-037721 — A group of potential antitumor arylnapthalene lactone derivatives, which may be developed as novel anticancer and immunostimulant agents.
Natural products and semi-synthetic derivatives derived from them have been used for anticancer drugs or drug leads for many years. However, side-effects such as myelosuppression and secondary leukemia have been reported. Furthermore, these natural products can be difficult to use for targeting sp…
- College: College of Pharmacy
- Inventors: Kinghorn, Alan "Dr. A. Douglas Kinghorn"; Fuchs, James; Huntsman, Andrew
- Licensing Officer: He, Panqing
Topical Compounds to Treat Leishmania
TS-014819 — A new class of drugs for the treatment of Leishmania.
Leishmaniasis is an infection caused by Leishmania parasites, spread by the bite of phlebotomine sand flies. It is prevalent in the tropics, subtropics, and southern Europe and is considered a neglected disease. Over a million people are infected with the parasite yearly, leading to skin sores and i…
- College: College of Medicine (COM)
- Inventors: Satoskar, Abhay; Fuchs, James; Isaac-Marquez, Angelica; Kinghorn, Alan "Dr. A. Douglas Kinghorn"; Lezama-Davila, Claudio; Pan, Li
- Licensing Officer: Schultz, Teri
Silvestrol as an Immune Adjuvant for Vaccines
TS-014782 — Silvestrol promotes the prevention and treatment of various cancers as an immune adjuvant.
Molecular changes due to malignant tumors and toxicity of chemotherapeutic regimen suppress the immune system of cancer patients. This immunosuppression also leaves patients vulnerable to opportunistic infections and reactivation of latent viral or mycobacterial infections. Immunostimulation, or a…
- College: College of Medicine (COM)
- Inventors: Baiocchi, Robert; Grever, Michael; Kinghorn, Alan "Dr. A. Douglas Kinghorn"; Lucas, David; Patton, John
- Licensing Officer: He, Panqing
