# of Displayed Technologies: 10 / 11


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Junctional Tourniquet for Groin and Axillary Regions
TS-041808 — A tourniquet with a ratcheting lock to keep pressure on wounds in the groin and axillary regions. Hemostasis can be achieved while the patient is still in the field.
Patients with blood loss in the field need to be treated immediately to prevent ongoing blood loss, shock, and death; bleeding from extremity and junctional wounds is the leading cause of potentially preventable death from penetrating injuries. Direct manual pressure is effective for the initial c…
  • College: OSU Wexner Medical Center
  • Inventors: McElroy, James; Graham, Nadi; Nocera, Tanya
  • Licensing Officer: Flammang, Ann Marie

Method for producing therapeutic exosomes from nanoelectroporation based cell transfection
TS-038403 — A method for producing therapeutic extracellular vesicles that contain functional mRNAs, miRNAs and shRNAs, for non-endocytic deliver of DNA for applications in cancer treatment and regenerative medicine.
Numerous cell types secrete extracellular vesicles (EVs), including exosomes and microvesicles. Exosomes are nano-vesicles (40–150 nm), and contain both coding and non-coding RNAs and their fragments, DNA fragments, proteins, and other cell related biomolecules. EVs and their biomolecule con…
  • College: College of Engineering (COE)
  • Inventors: Lee, L James; Shi, Junfeng; Yang, Zhaogang
  • Licensing Officer: Norris, Francis "Frank"

A Gas-Assisted Resin Injection Technique for Bonding and Surface Modification of Microfluidic Devices
TS-037577 — A new resin gas-assisted injection technique, which can achieve both bonding and surface modification of microfluidic devices
The application of microfluidic platforms is limited because the materials and production methods are too expensive, and the material properties induce problems, such as a lack of optical clarity and low impact strength. Packaging (i.e. sealing a device with a lid) is also a challenge in the fabri…
  • College: College of Engineering (COE)
  • Inventors: Lee, L James; Lai, Siyi
  • Licensing Officer: Norris, Francis "Frank"

Carbon Dioxide Assisted Processing and Bonding of Polymer and Polymer Composites
TS-037400 — A novel method to bond polymer composites without the use of heat or organic solvents.
Application of either heat or organic solvents is critical to convert solid materials to fluids. For many applications, particularly biomedical products, high temperature and organic solvents may denature critical biomolecules. Residue of organic solvents may also cause severe contamination. In ad…
  • College: College of Engineering (COE)
  • Inventors: Lee, L James; Tomasko, David; Yang, Yong; Zeng, Changchun
  • Licensing Officer: Norris, Francis "Frank"

Nanoparticle and Long Fiber Reinforced Thermoset Nanocomposites
TS-037388 — A method to combine the advantages of both fiber reinforced plastics and polymer nanocomposites to produce a superior composite material.
Dispersion of nanoparticles into fiber reinforced plastics (FRPs) produces superior composites. Current methods face two problems: (1) best practices to disperse nanoparticles FRPs are not defined and (2) methods to maintain resin processability in the presence of nanoparticles are not understood.…
  • College: College of Engineering (COE)
  • Inventors: Lee, L James; Cao, Xia; Zhou, Gang
  • Licensing Officer: Norris, Francis "Frank"

Synthesis and Foaming of Water Containing Activated Carbon-Nano/Microparticulate Polystyrene
TS-037386 — A novel method to increase thermal efficiency infrared absorption and bulk density of polystyrene foams.
Blowing agents create a cellular structure from a liquid plastic resin and, in certain cases, function as an insulating component of the foam. Hydrogen-containing chlorofluorocarbons and fluorocarbons are common blowing agents in the foam industry for extrusion forming of Polystyrene foam. However…
  • College: College of Engineering (COE)
  • Inventors: Lee, L James; Chiou, Nan-Rong; Yang, Jintao; Yeh, Shu Kai
  • Licensing Officer: Norris, Francis "Frank"

Fabrication of Nanopapers and Nanoparticle Reinforced Polymeric Composites Using Vacuum-Assisted Layer-by-Layer Spraying Technique
TS-037364 — A method to combine advantages of fiber-reinforced plastics and nanocomposites to produce a low-cost, superior lightweight material.
Nanomaterials, more specifically nanoparticle reinforced composites, are one of the best solutions for most lightweight applications. Due to the dispersion and high aspect ratio of nanoparticles, lightweight polymer nanocomposites exhibit dimensional stability, heat and flame resistance, barrier p…
  • College: College of Engineering (COE)
  • Inventors: Lee, L James; Guerra, Dante; Min, Yong Gang; Movva, Siva
  • Licensing Officer: Norris, Francis "Frank"

Tethered Liposomal Nanoparticle (tLN) Microarray Chips Containing Molecular Probes for Simultaneous Cell Sorting and Bio Detection
TS-037347 — A simple, and efficient method for identifying intra-cellular biomarkers for the targeted treatment of disease.
Tethered Lipoplex Nanoparticle (TLN) microarray biochips simultaneously capture and identify extracellular vesicles (EV) RNA targets from human plasma or bodily fluids with or without EV isolation. Molecular detection probes, such as molecular beacons (MBs), identify specific micro RNA (miRNA) or …
  • College: College of Engineering (COE)
  • Inventors: Lee, L James; Kwak, Kwang Joo; Lee, Andrew; Wu, Yun; Yu, Bo
  • Licensing Officer: Norris, Francis "Frank"

Carbide bonded Graphene Coating
TS-015271 — A facile approach for obtaining carbide-bonded graphene coatings on a variety of metallic and nonmetallic substrates.
Despite the many attractive features of graphene, the lack of atomic bonds between graphene and substrates and among graphene nanosheets has limited its potential applications. Although theoretical considerations predict that covalent bonds between graphene nanosheets would significantly improve s…
  • College: College of Engineering (COE)
  • Inventors: Lee, L James; Huang, Wenyi; Yu, Jianfeng
  • Licensing Officer: Norris, Francis "Frank"

Oral Hydrogel Drug Delivery Agents
TS-014913 — A novel methodology for the production of polymeric particle-like drug delivery devices
Currently, the six common drug delivery mechanisms are oral, topical, injection, pulmonary administration, transmucosal, and transdermal. Advanced drug delivery include sustained/extended release, prodrugs, targeted, polymeric, implants, and IUDs. Polymeric drug delivery systems are provide a prom…
  • College: College of Engineering (COE)
  • Inventors: Lee, L James; Guan, Jingjiao; Hansford, Derek
  • Licensing Officer: Norris, Francis "Frank"

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