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Novel Quantitative Method to Detect Mold Growth in Buildings
TS-066963 — The Need Exposure to mold in homes costs billions of dollars every year. Exposure is particularly harmful to the 8% of the United States population that suffers from asthma; a leading cause of disability in children. Currently, odor, visible mold growth, and dampness are the best indicators of mold…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Balasubrahmaniam, Neeraja; Bope, Ashleigh
  • Licensing Officer: Ashouripashaki, Mandana

Dust Analysis: A Novel Approach to Monitoring Viral Spread
TS-066962 — The Need Viral disease (such as influenza viruses and SARS-CoV-2) surveillance in high-risk settings faces several challenges, such as asymptomatic carriers, incomplete reporting, resource limitations, and delayed diagnosis of traditional swab test methods. These challenges could allow a virus to s…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Faith, Seth; Hull, Natalie; Nastasi, Nick; Renninger, Nicole
  • Licensing Officer: Ashouripashaki, Mandana

Smartphone Detection Kit for Airborne Formaldehyde and Allergens
TS-066960 — The Need Indoor air can be polluted by various sources, including building materials, furniture, cleaning products, and even people. Exposure to these resulting contaminants and allergens can lead to a variety of health problems, such as respiratory irritation, allergies, and even cancer. It is cur…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Parquette, Jonathan; Qin, Rongjun
  • Licensing Officer: Ashouripashaki, Mandana

Color Correction System for Accurate Colorimetric Smartphone Measurements
TS-066957 — The Need Colorimetric tests and remote image analysis are used in a wide range of industrial and medical applications. Digital image-based measurements made with smartphones are a promising platform to quantify colors at low cost, but suffer from inconsistency and errors caused by lens quality, sen…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Panescu, Jenny; Qin, Rongjun; Song, Shuang; Zhang, Guixiang
  • Licensing Officer: Ashouripashaki, Mandana

Unveiling the Nanoscale: Breakthrough Analytical Speed of Real-Time Super-Resolution Microscopy and Beyond
TS-066926 — This Ohio State University software innovation offers groundbreaking analytical speed and automation of Single-Molecule Localization Microscopy (SMLM) as well as analysis of 3D data and images extending beyond the field of microscopy. Our technology offers real-time spatial analysis in continuous and discrete space, enabling unprecedented speed and efficiency in data processing that translates into faster decision-making, high-throughput screening capabilities, and broad applicability beyond traditional microscopy.
Single-molecule localization microscopy (SMLM) describes a family of fast-evolving, powerful imaging techniques that dramatically improve spatial resolution over standard, diffraction-limited microscopy techniques and can image biological structures at the molecular scale. SMLM can now be performe…
  • College: College of Engineering (COE)
  • Inventors: Soltisz, Andrew; Veeraraghavan, Rengasayee
  • Licensing Officer: Zinn, Ryan

Humanized SSTR2 mAb and ADC to target SSTR2+ tumors
TS-066912 — Targeted humanized mAbs and ADCs for cancer treatment
The Liu Lab Dr. Xiaoguang “Margaret” Liu applies her industry experience (Lonza, Merck, and Life Technologies) in cell line and process development towards her lab’s focus on targeted anti-cancer therapies including monoclonal antibodies, antibody-drug conjugates, and gene therapi…
  • College: College of Engineering (COE)
  • Inventors: Liu, Xiaoguang "Margaret"; Zhou, Lufang
  • Licensing Officer: Schworer, Adam

Advanced Sensor Housing for Environmental Monitoring in Precision Agriculture and Beyond
TS-066793 — The Need In agriculture, the accurate measurement of gasses such as nitrous oxide (N2O) and nitrogen oxides (NOx) is crucial for optimizing fertilizer use, minimizing greenhouse gas emissions, and reducing air pollution. Current monitoring technologies are often expensive, complex, and not suitable…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Khanal, Sami; Bevers, Noah; Shearer, Scott; Tkach, Chris
  • Licensing Officer: Dahlman, Jason "Jay"

Small Molecule USP30 Inhibitors for the Treatment and Prevention of Cardiomyopathy
TS-066773 — The Need Cardiomyopathy, a disease of the heart muscle, poses significant public health challenges due to its diverse causes, symptoms, and potential complications, including heart failure and arrhythmias. With cardiomyopathy often induced by drugs, such as anthracyclines used in chemotherapy, ther…
  • College: College of Medicine (COM)
  • Inventors: Sun, Nuo; Krigman, Judith; Yang, Mingchong; Zhang, Ruohan
  • Licensing Officer: Willson, Christopher

Biofilm Detachment Monitoring for Enhanced Oral Health Solutions
TS-066772 — The Need Biofilms, particularly dental plaque-biofilms, are communities of microorganisms encased in a slimy extracellular polymeric substance (EPS) that adhere to surfaces or neighboring microorganisms. These biofilms are responsible for various infectious diseases, including oral diseases such as…
  • College: College of Medicine (COM)
  • Inventors: Stoodley, Paul; Gloag, Erin
  • Licensing Officer: Willson, Christopher

Innovative Biomarker Technology for Detecting and Treating Endothelial Injury in Neurological Disorders
TS-066771 — Endothelial injury is a significant pathological mechanism underlying various neurological disorders, including neurodegenerative, neuroinflammatory, and cerebrovascular diseases. Current clinical and research settings lack reliable biomarkers to detect or measure endothelial injury in the human C…
  • College: College of Medicine (COM)
  • Inventors: Al Tarawneh, Rawan
  • Licensing Officer: Willson, Christopher

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