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Capacitive Sensing Method for Integrated Circuit Identification and Authentication
TS-048641 — A method of authenticating an IC die’s origin and uniquely identifying each die with an intrinsic unclonable value through measurement of on-chip capacitance values
Hardware security in Integrated Circuit (IC) designs is of increasing importance in dealing with the insecure, expanding global supply chain of these parts. The ability to trace the origin of a die, combined with the capability to uniquely identify each die provides valuable quantitative measures …
  • College: College of Engineering (COE)
  • Inventors: Khalil, Waleed; Kines, Michael
  • Licensing Officer: Hong, Dongsung

Apoprotein manufacturing and methods for protein purification
TS-046794 — Methods of purifying proteins that can be used in various applications such as drug delivery and detoxification of byproducts of hemolysis.
Novel protein and apoprotein purification strategies are valuable tools with a wide variety of medical and research applications. While there are existing techniques for protein and apoprotein purification, some of these have flaws such as the use of harsh denaturants, highly flammable solvents, l…
  • College: College of Engineering (COE)
  • Inventors: Susin Pires, Ivan; Belcher, Donald; Palmer, Andre
  • Licensing Officer: Davis, Stewart

Nanoparticle Composition for Nucleic Acid Delivery
TS-044109 — Lipid nanoparticles (LNs) usable for the delivery of therapeutic compositions, including, but not limited to nucleic acids (NAs).
Nucleic Acid (NA) based therapies are used to inhibit gene expression. Lipid nanoparticles (LNs) are capable of carrying these therapies into cells. However, this delivery requires overcoming several physiological barriers. For instance, one barrier is the acidic endosome conditions within the cel…
  • College: College of Pharmacy
  • Inventors: Lee, Robert
  • Licensing Officer: Flammang, Ann Marie

DNA-cage erasable labels for fluorescence-based imaging
TS-043819 — Compositions and methods for analyzing multiple biomarkers without damaging tissue.
Histopathology is a cornerstone of tissue analysis used to diagnose many clinical conditions. Many of these diagnoses are based on identifying the presence of specific biomarkers, which can be indicated by colored labels. Currently, only 1-2 markers can be analyzed per slide, reducing accuracy and…
  • College: College of Engineering (COE)
  • Inventors: Winter, Jessica; Jergens, Elizabeth; Lee, Kil Ho "Kilho"
  • Licensing Officer: Zinn, Ryan

Identifying the level of lupus patients’ comprehension of their medication regimens and disease outcomes
TS-040132 — A questionnaire used to understand a patient’s comprehension of their personalized medication plan and the disease fluctuation of systemic lupus erythematous (SLE).
Systemic lupus erythematous (SLE) is an autoimmune disease in which the body’s immune system attacks healthy tissue in its own body. The disease has a prevalance of twenty to 150 cases per 100,000 individuals, and is more common in females than in men. This chronic disease has no cure, and s…
  • College: College of Medicine (COM)
  • Inventors: Meara, Alexa; Ardoin, Stacy; Peters, Ellen
  • Licensing Officer: Davis, Stewart

STAT3 Inhibitors and Their Anti-Cancer Usage
TS-037671 — Novel non-peptidomimetic molecules for use as anti-cancer inhibitors of signal transducer and activator of transcription 3.
The search for more potent drug delivery candidates for cancer therapy remains a challenge within the medical community. Efforts to target cancer at the genetic level have led to numerous discoveries, including the role that constitutive activation of signal transducer and activator of transcripti…
  • College: College of Pharmacy
  • Inventors: Li, Chenglong; Lin, Jiayuh; Yu, Wenying
  • Licensing Officer: Flammang, Ann Marie

Al-Cr-Ti-V Based High Entropy Alloys
TS-037543 — Innovative alloys displaying extremely high strength and improving upon other mechanical properties
High entropy alloys (HEA) are a new class of multiple-principle-element alloys stabilized by large configurational entropy. HEA offer exceptional mechanical, chemical, and magnetic properties at room and elevated temperatures. Current efforts in the HEA field have focused on developing new materia…
  • College: College of Engineering (COE)
  • Inventors: Luo, Aihua (Alan); Huang, Xuejun; Sun, Weihua
  • Licensing Officer: Bartell, Cordellia

Fabrication of Nanopapers and Nanoparticle Reinforced Polymeric Composites Using Vacuum-Assisted Layer-by-Layer Spraying Technique
TS-037364 — A method to combine advantages of fiber-reinforced plastics and nanocomposites to produce a low-cost, superior lightweight material.
Nanomaterials, more specifically nanoparticle reinforced composites, are one of the best solutions for most lightweight applications. Due to the dispersion and high aspect ratio of nanoparticles, lightweight polymer nanocomposites exhibit dimensional stability, heat and flame resistance, barrier p…
  • College: College of Engineering (COE)
  • Inventors: Lee, L James; Guerra, Dante; Min, Yong Gang; Movva, Siva
  • Licensing Officer: Norris, Francis "Frank"

Tethered Liposomal Nanoparticle (tLN) Microarray Chips Containing Molecular Probes for Simultaneous Cell Sorting and Bio Detection
TS-037347 — A simple, and efficient method for identifying intra-cellular biomarkers for the targeted treatment of disease.
Tethered Lipoplex Nanoparticle (TLN) microarray biochips simultaneously capture and identify extracellular vesicles (EV) RNA targets from human plasma or bodily fluids with or without EV isolation. Molecular detection probes, such as molecular beacons (MBs), identify specific micro RNA (miRNA) or …
  • College: College of Engineering (COE)
  • Inventors: Lee, L James; Kwak, Kwang Joo; Lee, Andrew; Wu, Yun; Yu, Bo
  • Licensing Officer: Norris, Francis "Frank"

Battery consumption minimization strategy for plug-in, pure, and hybrid EVs
TS-036908 — An energy management strategy for pure and hybrid electric vehicles that improves battery-life and optimizes fuel economy
Automotive powertrains are increasingly more electric, from mild and full hybrid, to plug-in hybrid and battery electric, automotive propulsion is increasingly relying on electricity as a source of power assist, or as the sole source of power, in automotive vehicles. This is true for passenger, co…
  • College: College of Engineering (COE)
  • Inventors: Rizzoni, Giorgio; Tang, Li
  • Licensing Officer: Zinn, Ryan

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