Available Technologies
# of Displayed Technologies: 2 / 2
Autophagosome-Lysosome Fusion Inhibition Enhances Flavopiridol Efficacy in Cancer
TS-037639 — A novel method to increase the effectiveness and practicality of the cancer treatment drug Flavopiridol.
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia and the current therapies are not curative. High-risk genetic modifications are associated with poor response to traditional therapies. Flavopiridol, a broad-spectrum cyclin-dependent kinase inhibitor, activates significant clini…
- College: College of Medicine (COM)
- Inventors: Byrd, John; Grever, Michael; Johnson, Amy; Lucas, David; Mahoney, Emilia
- Licensing Officer: Taysavang, Panya
Silvestrol as an Immune Adjuvant for Vaccines
TS-014782 — Silvestrol promotes the prevention and treatment of various cancers as an immune adjuvant.
Molecular changes due to malignant tumors and toxicity of chemotherapeutic regimen suppress the immune system of cancer patients. This immunosuppression also leaves patients vulnerable to opportunistic infections and reactivation of latent viral or mycobacterial infections. Immunostimulation, or a…
- College: College of Medicine (COM)
- Inventors: Baiocchi, Robert; Grever, Michael; Kinghorn, Alan "Dr. A. Douglas Kinghorn"; Lucas, David; Patton, John
- Licensing Officer: He, Panqing
