RAFT Agents for Controlled Radical Polymerization of Biofunctionalized Polymeric Materials
TS-068081 — These RAFT agents enable synthesis of novel polymer materials with enhanced biocompatibility and tailored functionality, suited for a wide range of biomedical applications.
Background
The growing demand for biofunctionalized polymer materials in fields such as drug delivery and diagnostics requires precise control over polymer properties. However, current reagents for Reversible Addition Fragmentation chain Transfer (RAFT) polymerization struggle with achieving the ne…
- College: College of Arts & Sciences
- Inventors: Kulkarni, Anuja; Watkins, Davita
- Licensing Officer: Panic, Ana
Direct Analysis of Air and Water Sensitive Material by In-Chamber Ionization Mass Spectrometry
TS-067160 — The Need
Due to the unparalleled ability of Mass spectrometry (MS) to identify and quantify substances at the molecular level it is an indispensable tool in various industries, from pharmaceuticals and forensics to environmental monitoring and materials science. However, the power of MS is often hi…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Hadad, Christopher; Lalisse, Remy; Sahraeian, Taghi; Wu, Yiying; Zheng, Jingfeng
- Licensing Officer: Panic, Ana
Co-Axial Contained Electrospray Ionization Platform for Mass Spectrometry
TS-067158 — The Need
Mass spectrometry (MS) is used across a wide range of applications for detection of various chemical analytes such as drug metabolites, pesticides, food adulterants, and natural product extracts. Recent developments have transformed MS into an all-purpose technique for in-situ and real-tim…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Burris, Benjamin "Ben"; Grooms, Alex; Heiss, Derik; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Advanced Mass Spectrometry Hybrid Ionization Technology for Comprehensive Molecular Analysis
TS-066752 —
In today's fast-paced commercial and scientific environments, there is an increasing demand for precise and efficient analytical techniques capable of handling complex mixtures with diverse physicochemical properties. Existing ionization techniques like Electrospray Ionization (ESI) and Atmosp…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Damale, Purva; Grooms, Alex; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Revolutionizing Hydrogen Production and CO2 Capture for a Sustainable Future
TS-065143 — The Need:
In the face of pressing environmental concerns and the imperative for sustainable energy solutions, there arises a critical commercial need for systems and methods that can efficiently produce hydrogen (H2) while simultaneously capturing and converting carbon dioxide (CO2) emissions. Trad…
- College: College of Arts & Sciences
- Inventors: Baker, Lawrence "Robert"
- Licensing Officer: Panic, Ana
Wearable Sensors for Touch-Based Collaboration and Digital Gaming
TS-064825 — he Need
In today's fast-paced and interconnected world, seamless collaboration among individuals is crucial for driving productivity and innovation. Traditional methods of interaction often fall short in capturing the nuances of human collaboration, leading to inefficiencies and misunderstandin…
- College: College of Engineering (COE)
- Inventors: Kiourti, Asimina; King, Cameron; Swearingen, EunKyoung "Kyoung"; Swearingen, Scott; Thrane, Susan; Williamson, Ian
- Licensing Officer: Panic, Ana
Revolutionizing Pharmaceutical Synthesis: Advancements in Metal-Catalyzed Coupling Technology
TS-064824 — The Need
In the pharmaceutical industry, the synthesis of complex organic substrates is crucial for the development of life-saving medications. However, traditional metal-catalyzed coupling reactions often face significant challenges when applied to these complex substrates, leading to high failure…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Dinh, Long; Hamby, Taylor; Starbuck, Hunter
- Licensing Officer: Panic, Ana
Electrocatalytic grafting and modification of polyvinylchlorides and chloroparaffins
TS-064268 —
Polyvinylchloride (PVC) is a widely used plastic, but its inherent limitations—brittleness, thermal instability, and poor shear strength—pose significant challenges for diverse applications, from medical packaging to construction. Conventional PVC modification relies on high loadings o…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Truesdell, Blaise
- Licensing Officer: Panic, Ana
A nitrogenase-like enzyme system that catalyzes methionine, ethylene, and methane biogenesis
TS-064265 —
In industrial settings, the demand for safe and efficient methods of producing ethylene, ethane, and methane is paramount. Existing ethylene production processes often involve oxygen-dependent enzymes, resulting in a flammable ethylene-oxygen gas mixture. Moreover, methane and ethane, when mixed w…
- College: College of Arts & Sciences
- Inventors: North, Justin; Murali, Srividya; Tabita, Fred (Bob) "Bob"; Young, Sarah
- Licensing Officer: Panic, Ana
Unique Panoptic Ion Source for Analyzing Complex Mixtures with Mass Spectroscopy
TS-062577 — Mass spectrometry (MS) is a widely used research tool for determining the exact molecular weight of particles within a sample. It separates electrically charged ions within a gas phase that are subsequently transferred into a mass analyzer, where they are sorted in space or time according to their m…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Amoah, Enoch; Chintalapudi, Kavyasree "Kavya"; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Sensor for detecting Viruses
TS-062553 — The Need
The swift and accurate diagnosis of COVID-19 and other viruses is crucial in preventing their spread. Current detection methods like PCR and antibody testing have limitations, including long run times, sample preparation, and high false negative rates. Moreover, with the rapid mutation and…
- College: College of Arts & Sciences
- Inventors: Schultz, Zachary; Payne, Taylor
- Licensing Officer: Panic, Ana
Development of Thread Spray Ambient Mass Spectrometry
TS-062337 — The Need: The healthcare industry is witnessing rapid changes, and the establishment of biobanks to collect and store biological specimens has become crucial for facilitating research and healthcare advancements. However, current microsampling techniques face challenges such as handling small sample…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Jackson, Sierra; Swiner, Devin
- Licensing Officer: Panic, Ana
Collaborative Interaction System- Wearable Technology for Collaborative Interaction for Children with Disabilities
TS-062336 — The Need: Enhancing Collaborative Interaction for Children with Disabilities
Millions of children in the United States with physical or cognitive disabilities face challenges in participating fully in play and forming meaningful connections with their parents and caregivers. The lack of touch and c…
- College: College of Arts & Sciences
- Inventors: Swearingen, EunKyoung "Kyoung"; Kiourti, Asimina; Swearingen, Scott; Thrane, Susan
- Licensing Officer: Panic, Ana
Dual ligand systems for cross-coupling of challenging C(sp2) and C(sp3) electrophiles.
TS-059018 — An unusual series of ligand exchange reactions establishes a dualcatalyst system for electroreductive alkyl-aryl cross-electrophile couplings of previously incompatible substrate combinations.
Cross-electrophile coupling (XEC) reactions of aryl and alkyl electrophiles are desirable methodologies for C–C bond formation but are limited to specific substrate classes. Couplings of widely-available electrophiles such as aryl chlorides or triflates are currently unknown with any alkyl b…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Hamby, Taylor
- Licensing Officer: Panic, Ana
Transition Metal Free Alkyne Hydrogenation and Semihydrogenation Catalysts
TS-058577 — Novel, transition metal-free catalysts capable of alkyne hydrogenation and semihydrogenation under modest conditions.
The Need
Numerous industrial processes require alkyne semihydrogenation or hydrogenation reactions. For example, hydrogenation is necessary for the industrial-scale synthesis vitamin A, the creation of high molecular weight polymers, and the processing of petroleum into functionally useful derivati…
- College: College of Arts & Sciences
- Inventors: Goldberger, Joshua; Hodge, Kelsey
- Licensing Officer: Panic, Ana
Redox Relay Flow Batteries: hybrid systems for scalable, high-capacity batteries.
TS-050105 — This application relates generally to a novel redox relay flow batteries comprising redox-active solids configured to behave as storage materials and redox-active organic molecules configured to behave as energy shuttles.
The Need
The growing global demand for electrical energy has increased research efforts towards the integration of renewable energy sources into the electrical grid. Generation of energy from petroleum-based sources dominates the current market, but dependence on renewable energy is expected to gro…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Wong, Curt
- Licensing Officer: Panic, Ana
Transition Metal Free Alkyne Hydrogenation and Semihydrogenation Catalysts
TS-048726 — Novel, transition metal-free catalysts capable of alkyne hydrogenation and semihydrogenation under modest conditions.
The Need
Numerous industrial processes require alkyne semihydrogenation or hydrogenation reactions. For example, hydrogenation is necessary for the industrial-scale synthesis vitamin A, the creation of high molecular weight polymers, and the processing of petroleum into functionally useful derivati…
- College: College of Arts & Sciences
- Inventors: Goldberger, Joshua; Hodge, Kelsey
- Licensing Officer: Panic, Ana
Paper-based Dried Blood Spheroids for Stabilization of Labile Organic Compounds Stored in Ambient Air
TS-038604 — Apparatus and methods to form three-dimensional dried blood spheroids on hydrophobic paper substrates.
Dried blood spots on paper substrates offer a facile sample collection, storage, and transportation approach for biofluids. However, variable diffusion, volcanic effects, analyte instability, and difficulty in recovering samples from paper plague this method, lowering confidence in analyte quantif…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Damon, Deidre
- Licensing Officer: Panic, Ana
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