RAFT Agents for Controlled Radical Polymerization of Biofunctionalized Polymeric Materials
TS-068081 — These RAFT agents enable synthesis of novel polymer materials with enhanced biocompatibility and tailored functionality, suited for a wide range of biomedical applications.
Background
The growing demand for biofunctionalized polymer materials in fields such as drug delivery and diagnostics requires precise control over polymer properties. However, current reagents for Reversible Addition Fragmentation chain Transfer (RAFT) polymerization struggle with achieving the ne…
- College: College of Arts & Sciences
- Inventors: Kulkarni, Anuja; Watkins, Davita
- Licensing Officer: Panic, Ana
Direct Analysis of Air and Water Sensitive Material by In-Chamber Ionization Mass Spectrometry
TS-067160 — The Need
Due to the unparalleled ability of Mass spectrometry (MS) to identify and quantify substances at the molecular level it is an indispensable tool in various industries, from pharmaceuticals and forensics to environmental monitoring and materials science. However, the power of MS is often hi…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Hadad, Christopher; Lalisse, Remy; Sahraeian, Taghi; Wu, Yiying; Zheng, Jingfeng
- Licensing Officer: Panic, Ana
Co-Axial Contained Electrospray Ionization Platform for Mass Spectrometry
TS-067158 — The Need
Mass spectrometry (MS) is used across a wide range of applications for detection of various chemical analytes such as drug metabolites, pesticides, food adulterants, and natural product extracts. Recent developments have transformed MS into an all-purpose technique for in-situ and real-tim…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Burris, Benjamin "Ben"; Grooms, Alex; Heiss, Derik; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Advanced Mass Spectrometry Hybrid Ionization Technology for Comprehensive Molecular Analysis
TS-066752 —
In today's fast-paced commercial and scientific environments, there is an increasing demand for precise and efficient analytical techniques capable of handling complex mixtures with diverse physicochemical properties. Existing ionization techniques like Electrospray Ionization (ESI) and Atmosp…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Damale, Purva; Grooms, Alex; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Revolutionizing Hydrogen Production and CO2 Capture for a Sustainable Future
TS-065143 — The Need:
In the face of pressing environmental concerns and the imperative for sustainable energy solutions, there arises a critical commercial need for systems and methods that can efficiently produce hydrogen (H2) while simultaneously capturing and converting carbon dioxide (CO2) emissions. Trad…
- College: College of Arts & Sciences
- Inventors: Baker, Lawrence "Robert"
- Licensing Officer: Panic, Ana
Sustainable and Efficient Hydrofunctionalization Catalysts
TS-064828 — The Need:
Efficient and selective hydrofunctionalization of alkenes via catalytic hydroboration, hydrogenation, or hydrosilylation address a critical demand in various chemical sectors. Particularly, in the petrochemical, pharmaceutical, agrochemical, and food industries these reactions play a piv…
- College: College of Arts & Sciences
- Inventors: Thomas, Christine; Fitzsimmons, Matthew
- Licensing Officer: Panic, Ana
Wearable Sensors for Touch-Based Collaboration and Digital Gaming
TS-064825 — he Need
In today's fast-paced and interconnected world, seamless collaboration among individuals is crucial for driving productivity and innovation. Traditional methods of interaction often fall short in capturing the nuances of human collaboration, leading to inefficiencies and misunderstandin…
- College: College of Engineering (COE)
- Inventors: Kiourti, Asimina; King, Cameron; Swearingen, EunKyoung "Kyoung"; Swearingen, Scott; Thrane, Susan; Williamson, Ian
- Licensing Officer: Panic, Ana
Revolutionizing Pharmaceutical Synthesis: Advancements in Metal-Catalyzed Coupling Technology
TS-064824 — The Need
In the pharmaceutical industry, the synthesis of complex organic substrates is crucial for the development of life-saving medications. However, traditional metal-catalyzed coupling reactions often face significant challenges when applied to these complex substrates, leading to high failure…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Dinh, Long; Hamby, Taylor; Starbuck, Hunter
- Licensing Officer: Panic, Ana
Electrocatalytic grafting and modification of polyvinylchlorides and chloroparaffins
TS-064268 —
Polyvinylchloride (PVC) is a widely used plastic, but its inherent limitations—brittleness, thermal instability, and poor shear strength—pose significant challenges for diverse applications, from medical packaging to construction. Conventional PVC modification relies on high loadings o…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Truesdell, Blaise
- Licensing Officer: Panic, Ana
A nitrogenase-like enzyme system that catalyzes methionine, ethylene, and methane biogenesis
TS-064265 —
In industrial settings, the demand for safe and efficient methods of producing ethylene, ethane, and methane is paramount. Existing ethylene production processes often involve oxygen-dependent enzymes, resulting in a flammable ethylene-oxygen gas mixture. Moreover, methane and ethane, when mixed w…
- College: College of Arts & Sciences
- Inventors: North, Justin; Murali, Srividya; Tabita, Fred (Bob) "Bob"; Young, Sarah
- Licensing Officer: Panic, Ana
Unique Panoptic Ion Source for Analyzing Complex Mixtures with Mass Spectroscopy
TS-062577 — Mass spectrometry (MS) is a widely used research tool for determining the exact molecular weight of particles within a sample. It separates electrically charged ions within a gas phase that are subsequently transferred into a mass analyzer, where they are sorted in space or time according to their m…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Amoah, Enoch; Chintalapudi, Kavyasree "Kavya"; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Sensor for detecting Viruses
TS-062553 — The Need
The swift and accurate diagnosis of COVID-19 and other viruses is crucial in preventing their spread. Current detection methods like PCR and antibody testing have limitations, including long run times, sample preparation, and high false negative rates. Moreover, with the rapid mutation and…
- College: College of Arts & Sciences
- Inventors: Schultz, Zachary; Payne, Taylor
- Licensing Officer: Panic, Ana
Development of Thread Spray Ambient Mass Spectrometry
TS-062337 — The Need: The healthcare industry is witnessing rapid changes, and the establishment of biobanks to collect and store biological specimens has become crucial for facilitating research and healthcare advancements. However, current microsampling techniques face challenges such as handling small sample…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Jackson, Sierra; Swiner, Devin
- Licensing Officer: Panic, Ana
Collaborative Interaction System- Wearable Technology for Collaborative Interaction for Children with Disabilities
TS-062336 — The Need: Enhancing Collaborative Interaction for Children with Disabilities
Millions of children in the United States with physical or cognitive disabilities face challenges in participating fully in play and forming meaningful connections with their parents and caregivers. The lack of touch and c…
- College: College of Arts & Sciences
- Inventors: Swearingen, EunKyoung "Kyoung"; Kiourti, Asimina; Swearingen, Scott; Thrane, Susan
- Licensing Officer: Panic, Ana
A Non-Chemical Method for Algal Bloom Treatment and Prevention
TS-059099 — SS+MEF technology to both prevent and treat algal bloom growth, as well as neutralize algal toxins.
The Need
Climate change and human practices have led to an increased frequency and intensity of Harmful Algal Blooms (HABs). These HABs, particularly those dominated by cyanobacteria, produce harmful toxins, which result in serious health issues when ingested, inhaled, or contacted. The stability of…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Sastry, Sudhir; Davis, Angela; Lee, Jiyoung; Mok, Jin Hong
- Licensing Officer: Panic, Ana
Dual ligand systems for cross-coupling of challenging C(sp2) and C(sp3) electrophiles.
TS-059018 — An unusual series of ligand exchange reactions establishes a dualcatalyst system for electroreductive alkyl-aryl cross-electrophile couplings of previously incompatible substrate combinations.
Cross-electrophile coupling (XEC) reactions of aryl and alkyl electrophiles are desirable methodologies for C–C bond formation but are limited to specific substrate classes. Couplings of widely-available electrophiles such as aryl chlorides or triflates are currently unknown with any alkyl b…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Hamby, Taylor
- Licensing Officer: Panic, Ana
Transition Metal Free Alkyne Hydrogenation and Semihydrogenation Catalysts
TS-058577 — Novel, transition metal-free catalysts capable of alkyne hydrogenation and semihydrogenation under modest conditions.
The Need
Numerous industrial processes require alkyne semihydrogenation or hydrogenation reactions. For example, hydrogenation is necessary for the industrial-scale synthesis vitamin A, the creation of high molecular weight polymers, and the processing of petroleum into functionally useful derivati…
- College: College of Arts & Sciences
- Inventors: Goldberger, Joshua; Hodge, Kelsey
- Licensing Officer: Panic, Ana
Redox Relay Flow Batteries: hybrid systems for scalable, high-capacity batteries.
TS-050105 — This application relates generally to a novel redox relay flow batteries comprising redox-active solids configured to behave as storage materials and redox-active organic molecules configured to behave as energy shuttles.
The Need
The growing global demand for electrical energy has increased research efforts towards the integration of renewable energy sources into the electrical grid. Generation of energy from petroleum-based sources dominates the current market, but dependence on renewable energy is expected to gro…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Wong, Curt
- Licensing Officer: Panic, Ana
Transition Metal Free Alkyne Hydrogenation and Semihydrogenation Catalysts
TS-048726 — Novel, transition metal-free catalysts capable of alkyne hydrogenation and semihydrogenation under modest conditions.
The Need
Numerous industrial processes require alkyne semihydrogenation or hydrogenation reactions. For example, hydrogenation is necessary for the industrial-scale synthesis vitamin A, the creation of high molecular weight polymers, and the processing of petroleum into functionally useful derivati…
- College: College of Arts & Sciences
- Inventors: Goldberger, Joshua; Hodge, Kelsey
- Licensing Officer: Panic, Ana
Development of a Single Component Methacrylate Adhesive Formulation
TS-042066 — A novel hybrid adhesive that combines the non-toxic, high strength properties of methacrylate adhesives with the bonding characteristics of polyurethanes
Despite the utility of methacrylate adhesive chemistry, applications have been limited to industrial and biomedical use cases. This is due to the curing mechanism, which is initiated by either heat, light or a two-component redox system. This invention describes two strategies to create a single-c…
- College: College of Arts & Sciences
- Inventors: Parquette, Jonathan; Schricker, Scott
- Licensing Officer: Panic, Ana
Paper-based Dried Blood Spheroids for Stabilization of Labile Organic Compounds Stored in Ambient Air
TS-038604 — Apparatus and methods to form three-dimensional dried blood spheroids on hydrophobic paper substrates.
Dried blood spots on paper substrates offer a facile sample collection, storage, and transportation approach for biofluids. However, variable diffusion, volcanic effects, analyte instability, and difficulty in recovering samples from paper plague this method, lowering confidence in analyte quantif…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Damon, Deidre
- Licensing Officer: Panic, Ana
Production of Galacto-oligosaccharides from Lactose by Enzyme Immobilized on Cotton Cloth
TS-037689 — Lactose from cheese whey is converted from a dairy byproduct to a useful prebiotic using enzymes immobilized on cotton cloth.
Galacto-oligosaccharides (GOS) are a collection of prebiotic fibers made of a chain of galactose sugars of variable length. GOS has been shown to exert some of the most potent and beneficial effects among prebiotic fibers. When added to infant formula, it can change bowel flora to approximate the …
- College: College of Engineering (COE)
- Inventors: Yang, Shang-Tian "ST"; Albayrak, Nedim
- Licensing Officer: Panic, Ana
Methods for Making Three Dimensional Microfluidic Bioreactor Array
TS-037642 — Design for a three-dimensional microfluidic bioreactor array; device allows for culturing of a variety of cell types without contamination.
Cell culture in a three-dimensional fluidic-flow microenvironment is critical for long-term cell-based assays. Conducting in vitro research offers an accessible, reproducible, and reliable mode of investigation for therapeutic decisions before work is conducted in vivo. However, because of the com…
- College: College of Engineering (COE)
- Inventors: Yang, Shang-Tian "ST"; Wen, Yuan
- Licensing Officer: Panic, Ana
Methods and Processes for Producing Butyrate Esters from Sugars
TS-037568 — A method and process for producing butyrate esters for use as novel biofuels.These products have a similar energy content to biobutanol, but are easier to produce.
Currently, bioethanol is the major biofuel on the market, but recently butanol has gotten attention for its potential as a transportation fuel. It has many characteristics that make it a better fuel source than ethanol: butanol has 25% more Btu per gallon, it's less evaporative/explosive with …
- College: College of Engineering (COE)
- Inventors: Yang, Shang-Tian "ST"
- Licensing Officer: Panic, Ana
Metabolic Engineering of Clostridium Tyrobutyricum for Butanol Production
TS-037555 — A new strain of bacteria that can produce butanol at a high titer for transportation fuel.
Butanol is generally used as an industrial solvent but can also be blended with gasoline and used as transportation fuel. Butanol is commonly produced using fossil fuels, but it can also be produced from biomass, referred to as biobutanol. Biobutanol is produced from fermentation of the same feeds…
- College: College of Engineering (COE)
- Inventors: Yang, Shang-Tian "ST"; Yu, Mingrui
- Licensing Officer: Panic, Ana
N-Proanol and Propionic Acid Producing Propionibacteria
TS-037515 — New method of producing n-propanol and propionic acid using a metabolically engineered propionibacteria.
Propionibacteria are well-known for their various industrial applications including the manufacturing of Swiss cheese, vitamin B12, and propionic acid. However, not much is known about their genetics, and few studies have been conducted utilizing them for metabolic engineering, mostly in vitamin B…
- College: College of Engineering (COE)
- Inventors: Yang, Shang-Tian "ST"; Ammar, Ehab
- Licensing Officer: Panic, Ana
Methods and Apparatus to estimate phase of radiofrequency field
TS-037437 — A technique for estimating magnetic resonance imaging absolute phase to enhance machine efficiency and versatility.
Estimating absolute phase of Radiofrequency (RF) field including both the transmit field and receive sensitivity is very important for various stages of the magnetic resonance imaging (MRI) procedure. It can be used for mulit-transmit, RF shimming, parallel imaging reconstruction, electric propert…
- College: College of Arts & Sciences
- Inventors: Wang, Jinghua; Ding, Yu
- Licensing Officer: Panic, Ana
CO2 Reduction to Acetate on Mixed Metal Oxide Catalyst
TS-037385 — A process for photoelectrochemical reduction of carbon dioxide to acetate using mixed metal oxide as catalysts
The combustion of fossil fuels produces billions of tons of carbon dioxide annually. Research indicates that greater concentrations of carbon dioxide in the atmosphere has altered Earth's climate, changed the pH of the ocean, and causing other potentially damaging evironmental effects. Countri…
- College: College of Arts & Sciences
- Inventors: Baker, Lawrence "Robert"; Yang, Xin
- Licensing Officer: Panic, Ana
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