From Pigment to Performance: Precision Melanin Supraparticles Powering Advanced Market Solutions
TS-071959 — Unlocking high-value nanomaterials for next-generation electronics, energy solutions, medical products, and environmental technologies.
Overview
Synthetic melanins have similar properties as lab-made carbon nanomaterials but are biocompatible and can be prepared sustainably. However, commercial adoption of melanin nanomaterials is hindered by limited size control, poor scale-up, and limited solubility, preventing use in advanced el…
- College: College of Arts & Sciences
- Inventors: Kohler, Bern; Empey-Kohl, Forrest; Grieco, Christopher; Madhu, Meera; Vaidyanathan, Adithya
- Licensing Officer: Panic, Ana
UZELA & Larval Settlement Modules: Advancing Coral Reef Restoration
TS-071766 — Empowering transformative change in marine ecosystems through innovation and collaboration.
Coral reefs, the cornerstone of marine biodiversity and coastal protection, are facing critical decline from climate change, disease, and anthropogenic pressures. Traditional restoration efforts often fall short due to high mortality and slow growth, leaving oceans and communities increasingly vul…
- College: College of Arts & Sciences
- Inventors: Grottoli, Andrea; Dixon, Shannon; Hulver, Ann Marie; Welter, Jacob
- Licensing Officer: Panic, Ana
Medusa: Intuitive 3D Audio Control for Immersive Sound Environments
TS-070311 —
Revolutionizing how professionals and creators interact with 3D audio-intuitively and inclusively.
Overview
As immersive audio becomes essential in virtual reality (VR), augmented reality (AR), and advanced formats like Dolby Atmos, the demand for precise, real-time 3D sound control is surging. Yet, traditional 2D knobs and touch screens fall short, especially for users with low vision, lim…
- College: College of Arts & Sciences
- Inventors: Hesmond, Michael
- Licensing Officer: Panic, Ana
Engineered Microbial Platforms for Continuous Biomanufacturing from Industrial CO₂ Streams
TS-070297 —
Transforming industrial waste gases into valuable biofuels and chemicals.
Overview:
Industrial sectors such as cement and petroleum refining are under increasing pressure to reduce greenhouse gas emissions while maintaining profitability. Our innovative technology leverages engineered strains of Cupriavidus necator to directly convert industrial waste carbon dioxide (C…
- College: College of Arts & Sciences
- Inventors: Tabita, Fred (Bob) "Bob"; Dangel, Andrew; Laguna, Rick; North, Justin; Young, Sarah
- Licensing Officer: Panic, Ana
RAFT Agents for Controlled Radical Polymerization of Biofunctionalized Polymeric Materials
TS-068081 — These RAFT agents enable synthesis of novel polymer materials with enhanced biocompatibility and tailored functionality, suited for a wide range of biomedical applications.
Background
The growing demand for biofunctionalized polymer materials in fields such as drug delivery and diagnostics requires precise control over polymer properties. However, current reagents for Reversible Addition Fragmentation chain Transfer (RAFT) polymerization struggle with achieving the ne…
- College: College of Arts & Sciences
- Inventors: Kulkarni, Anuja; Watkins, Davita
- Licensing Officer: Panic, Ana
Direct Analysis of Air and Water Sensitive Material by In-Chamber Ionization Mass Spectrometry
TS-067160 — The Need
Due to the unparalleled ability of Mass spectrometry (MS) to identify and quantify substances at the molecular level it is an indispensable tool in various industries, from pharmaceuticals and forensics to environmental monitoring and materials science. However, the power of MS is often hi…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Hadad, Christopher; Lalisse, Remy; Sahraeian, Taghi; Wu, Yiying; Zheng, Jingfeng
- Licensing Officer: Panic, Ana
Co-Axial Contained Electrospray Ionization Platform for Mass Spectrometry
TS-067158 — The Need
Mass spectrometry (MS) is used across a wide range of applications for detection of various chemical analytes such as drug metabolites, pesticides, food adulterants, and natural product extracts. Recent developments have transformed MS into an all-purpose technique for in-situ and real-tim…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Burris, Benjamin "Ben"; Grooms, Alex; Heiss, Derik; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Dynamic Spray Mass Spectrometry: A Versatile Solution for Comprehensive Molecular Analysis
TS-066752 — Background:
Mass spectrometry is an analytical technique characterized by its excellent sensitivity, robust selectivity, and rapid response. The four stages of mass spectrometry are ionization, acceleration, separation, and detection. Among these, the ionization step is crucial for analyzing comple…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Damale, Purva; Grooms, Alex; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Revolutionizing Hydrogen Production and CO2 Capture for a Sustainable Future
TS-065143 — The Need:
In the face of pressing environmental concerns and the imperative for sustainable energy solutions, there arises a critical commercial need for systems and methods that can efficiently produce hydrogen (H2) while simultaneously capturing and converting carbon dioxide (CO2) emissions. Trad…
- College: College of Arts & Sciences
- Inventors: Baker, Lawrence "Robert"
- Licensing Officer: Panic, Ana
Sustainable and Efficient Hydrofunctionalization Catalysts
TS-064828 — The Need:
Efficient and selective hydrofunctionalization of alkenes via catalytic hydroboration, hydrogenation, or hydrosilylation address a critical demand in various chemical sectors. Particularly, in the petrochemical, pharmaceutical, agrochemical, and food industries these reactions play a piv…
- College: College of Arts & Sciences
- Inventors: Thomas, Christine; Fitzsimmons, Matthew
- Licensing Officer: Panic, Ana
Wearable Sensors for Touch-Based Collaboration and Digital Gaming
TS-064825 — The Need
Human touch is vital to health and well-being, supporting stress reduction, emotional regulation, and healing from infancy through old age. In therapy and rehabilitation, it plays a critical role, yet is rarely measured. Sensors that detect human contact can both encourage touch and captur…
- College: College of Engineering (COE)
- Inventors: Kiourti, Asimina; King, Cameron; Swearingen, EunKyoung "Kyoung"; Swearingen, Scott; Thrane, Susan; Williamson, Ian
- Licensing Officer: Panic, Ana
Revolutionizing Pharmaceutical Synthesis: Advancements in Metal-Catalyzed Coupling Technology
TS-064824 — The Need
In the pharmaceutical industry, the synthesis of complex organic substrates is crucial for the development of life-saving medications. However, traditional metal-catalyzed coupling reactions often face significant challenges when applied to these complex substrates, leading to high failure…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Dinh, Long; Hamby, Taylor; Starbuck, Hunter
- Licensing Officer: Panic, Ana
Electrocatalytic grafting and modification of polyvinylchlorides and chloroparaffins
TS-064268 —
Polyvinylchloride (PVC) is a widely used plastic, but its inherent limitations—brittleness, thermal instability, and poor shear strength—pose significant challenges for diverse applications, from medical packaging to construction. Conventional PVC modification relies on high loadings o…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Truesdell, Blaise
- Licensing Officer: Panic, Ana
A nitrogenase-like enzyme system that catalyzes methionine, ethylene, and methane biogenesis
TS-064265 —
In industrial settings, the demand for safe and efficient methods of producing ethylene, ethane, and methane is paramount. Existing ethylene production processes often involve oxygen-dependent enzymes, resulting in a flammable ethylene-oxygen gas mixture. Moreover, methane and ethane, when mixed w…
- College: College of Arts & Sciences
- Inventors: North, Justin; Murali, Srividya; Tabita, Fred (Bob) "Bob"; Young, Sarah
- Licensing Officer: Panic, Ana
Panoptic Ion Source for Comprehensive Mass Spectrometry Analysis
TS-062577 — The Need
Traditional Mass Spectrometry (MS) methods require solid and liquid samples to be vaporized and charged before analysis, which can be limiting. Existing ion sources are often specialized for specific types of analytes, leading to inefficiencies and the need for multiple devices. There is a…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Amoah, Enoch; Chintalapudi, Kavyasree "Kavya"; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Sensor for detecting Viruses
TS-062553 — The Need
The swift and accurate diagnosis of COVID-19 and other viruses is crucial in preventing their spread. Current detection methods like PCR and antibody testing have limitations, including long run times, sample preparation, and high false negative rates. Moreover, with the rapid mutation and…
- College: College of Arts & Sciences
- Inventors: Schultz, Zachary; Payne, Taylor
- Licensing Officer: Panic, Ana
Unraveling Biomolecular Structures with Surface-Induced Dissociation Mass Spectrometry
TS-062550 — The Need: The need for surface-induced dissociation (SID) technology arises from the limitations of current mass spectrometric methods in studying the tertiary and quaternary structure of proteins and their complexes. While mass spectrometry is a powerful tool for structural biology, existing activa…
- College: College of Arts & Sciences
- Inventors: Wysocki, Vicki; Gilbert, Joshua; Harvey, Sophie; Jones, Benjamin; Stiving, Alyssa; VanAernum, Zachary "Zac"
- Licensing Officer: Panic, Ana
Thread-Based Immunoassay and Mass Spectrometry for Disease Biomarker Detection
TS-062337 — Background:
Current immunoassay methods often rely on magnetic beads for sample collection and signal amplification, typically employing colorimetric detection based on enzymatic reactions. This approach raises stability concerns and is not ideal for field analysis due to the necessity of lasers fo…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Jackson, Sierra; Swiner, Devin
- Licensing Officer: Panic, Ana
Collaborative Interaction System- Wearable Technology for Collaborative Interaction for Children with Disabilities
TS-062336 — The Need: Enhancing Collaborative Interaction for Children with Disabilities
Millions of children in the United States with physical or cognitive disabilities face challenges in participating fully in play and forming meaningful connections with their parents and caregivers. The lack of touch and c…
- College: College of Arts & Sciences
- Inventors: Swearingen, EunKyoung "Kyoung"; Kiourti, Asimina; Swearingen, Scott; Thrane, Susan
- Licensing Officer: Panic, Ana
A Non-Chemical Method for Algal Bloom Treatment and Prevention
TS-059099 — SS+MEF technology to both prevent and treat algal bloom growth, as well as neutralize algal toxins.
The Need
Climate change and human practices have led to an increased frequency and intensity of Harmful Algal Blooms (HABs). These HABs, particularly those dominated by cyanobacteria, produce harmful toxins, which result in serious health issues when ingested, inhaled, or contacted. The stability of…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Sastry, Sudhir; Davis, Angela; Lee, Jiyoung; Mok, Jin Hong
- Licensing Officer: Panic, Ana
Dual ligand systems for cross-coupling of challenging C(sp2) and C(sp3) electrophiles.
TS-059018 — An unusual series of ligand exchange reactions establishes a dualcatalyst system for electroreductive alkyl-aryl cross-electrophile couplings of previously incompatible substrate combinations.
Cross-electrophile coupling (XEC) reactions of aryl and alkyl electrophiles are desirable methodologies for C–C bond formation but are limited to specific substrate classes. Couplings of widely-available electrophiles such as aryl chlorides or triflates are currently unknown with any alkyl b…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Hamby, Taylor
- Licensing Officer: Panic, Ana
Transition Metal Free Alkyne Hydrogenation and Semihydrogenation Catalysts
TS-058577 — Novel, transition metal-free catalysts capable of alkyne hydrogenation and semihydrogenation under modest conditions.
The Need
Numerous industrial processes require alkyne semihydrogenation or hydrogenation reactions. For example, hydrogenation is necessary for the industrial-scale synthesis vitamin A, the creation of high molecular weight polymers, and the processing of petroleum into functionally useful derivati…
- College: College of Arts & Sciences
- Inventors: Goldberger, Joshua; Hodge, Kelsey
- Licensing Officer: Panic, Ana
Transition Metal Free Alkyne Hydrogenation and Semihydrogenation Catalysts
TS-048726 — Novel, transition metal-free catalysts capable of alkyne hydrogenation and semihydrogenation under modest conditions.
The Need
Numerous industrial processes require alkyne semihydrogenation or hydrogenation reactions. For example, hydrogenation is necessary for the industrial-scale synthesis vitamin A, the creation of high molecular weight polymers, and the processing of petroleum into functionally useful derivati…
- College: College of Arts & Sciences
- Inventors: Goldberger, Joshua; Hodge, Kelsey
- Licensing Officer: Panic, Ana
A Super Glue without the Toxicity Concerns
TS-042066 — Single-Component, Contact-Pressure Activated Adhesive
The Need
The adhesive market encompasses a wide range of technologies and uses; however, many existing adhesives face significant drawbacks. Common issues include toxicity and flammability, complex application processes requiring precise measuring and mixing, poor performance in low temperatures an…
- College: College of Arts & Sciences
- Inventors: Parquette, Jonathan; Schricker, Scott
- Licensing Officer: Panic, Ana
Paper-based Dried Blood Spheroids for Stabilization of Labile Organic Compounds Stored in Ambient Air
TS-038604 — Apparatus and methods to form three-dimensional dried blood spheroids on hydrophobic paper substrates.
Dried blood spots on paper substrates offer a facile sample collection, storage, and transportation approach for biofluids. However, variable diffusion, volcanic effects, analyte instability, and difficulty in recovering samples from paper plague this method, lowering confidence in analyte quantif…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Damon, Deidre
- Licensing Officer: Panic, Ana
Production of Galacto-oligosaccharides from Lactose by Enzyme Immobilized on Cotton Cloth
TS-037689 — Lactose from cheese whey is converted from a dairy byproduct to a useful prebiotic using enzymes immobilized on cotton cloth.
Galacto-oligosaccharides (GOS) are a collection of prebiotic fibers made of a chain of galactose sugars of variable length. GOS has been shown to exert some of the most potent and beneficial effects among prebiotic fibers. When added to infant formula, it can change bowel flora to approximate the …
- College: College of Engineering (COE)
- Inventors: Yang, Shang-Tian "ST"; Albayrak, Nedim
- Licensing Officer: Panic, Ana
Methods for Making Three Dimensional Microfluidic Bioreactor Array
TS-037642 — Design for a three-dimensional microfluidic bioreactor array; device allows for culturing of a variety of cell types without contamination.
Cell culture in a three-dimensional fluidic-flow microenvironment is critical for long-term cell-based assays. Conducting in vitro research offers an accessible, reproducible, and reliable mode of investigation for therapeutic decisions before work is conducted in vivo. However, because of the com…
- College: College of Engineering (COE)
- Inventors: Yang, Shang-Tian "ST"; Wen, Yuan
- Licensing Officer: Panic, Ana
Methods and Processes for Producing Butyrate Esters from Sugars
TS-037568 — A method and process for producing butyrate esters for use as novel biofuels.These products have a similar energy content to biobutanol, but are easier to produce.
Currently, bioethanol is the major biofuel on the market, but recently butanol has gotten attention for its potential as a transportation fuel. It has many characteristics that make it a better fuel source than ethanol: butanol has 25% more Btu per gallon, it's less evaporative/explosive with …
- College: College of Engineering (COE)
- Inventors: Yang, Shang-Tian "ST"
- Licensing Officer: Panic, Ana
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