Fungal Biocontrol Agents for Sustainable Resistance Management of Soybean Cyst Nematode Populations
TS-068701 — Novel fungal antagonists that suppress soybean cyst nematode (SCN) populations offer a natural solution that improves soil health and integrates into existing farming practices.
Background
The soybean cyst nematode (SCN) is the leading cause of yield loss in global soybean production, resulting in billions of dollars in economic damage annually. Traditional management strategies, including crop rotation and resistant cultivars are becoming less effective as SCN adapts and…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Medina Lopez, Melanie; Benitez Ponce, Maria Soledad; Lopez Nicora, Horacio
- Licensing Officer: Panic, Ana
A new modular format for bispecific antibody fragments
TS-068425 — Functionalization of scFvs with cyclic peptide linkers
The Need
The high specificity of antibodies has been utilized to develop numerous technologies, tools and therapeutics, like ADCs and radiopharmaceuticals. Engineered antibody fragments like single-chain variable fragments (scFvs) are starting to see their way into the clinic in BiTEs and CAR T. Sc…
- College: College of Arts & Sciences
- Inventors: Magliery, Thomas; Do, Jamie; Han, Jeong Min "Mina"; Zhu, Ian
- Licensing Officer: Panic, Ana
Noninvasive Rapid Radiation Exposure Assay
TS-068290 — The Need
Radiation exposure poses significant health risks, including cancer and other illnesses, making it crucial for clinicians to accurately measure and assess the extent of radiation exposure. Existing methods often require invasive procedures and may not detect exposure at lower dose ranges.
…
- College: College of Arts & Sciences
- Inventors: Schultz, Zachary; Jacob, Naduparambil; Morder, Courtney; Witte, Spencer
- Licensing Officer: Panic, Ana
Enzymatic Inhibitor for Control of Enteric Methane Emission by Ruminants
TS-068275 —
The small molecule inhibitor targets methanogenic archaea in the rumen, offering a novel and sustainable solution to significantly reduce methane emissions from ruminants.
Background
Atmospheric methane levels have doubled over the past century, driven largely by emissions from ruminant…
- College: College of Arts & Sciences
- Inventors: Gopalan, Venkat
- Licensing Officer: Panic, Ana
RAFT Agents for Controlled Radical Polymerization of Biofunctionalized Polymeric Materials
TS-068081 — These RAFT agents enable synthesis of novel polymer materials with enhanced biocompatibility and tailored functionality, suited for a wide range of biomedical applications.
Background
The growing demand for biofunctionalized polymer materials in fields such as drug delivery and diagnostics requires precise control over polymer properties. However, current reagents for Reversible Addition Fragmentation chain Transfer (RAFT) polymerization struggle with achieving the ne…
- College: College of Arts & Sciences
- Inventors: Kulkarni, Anuja; Watkins, Davita
- Licensing Officer: Panic, Ana
Reed Held: Precision Practice Tool for Oboists
TS-067289 — The Need
Oboists often struggle with fundamental elements of their playing, such as pitch accuracy, phrasing, and response, due to the complexity of managing the instrument as a whole. Traditional practice methods may not allow for the isolated focus necessary to correct these specific issues. Ther…
- College: College of Arts & Sciences
- Inventors: Held, Abby
- Licensing Officer: Panic, Ana
Direct Analysis of Air and Water Sensitive Material by In-Chamber Ionization Mass Spectrometry
TS-067160 — The Need
Due to the unparalleled ability of Mass spectrometry (MS) to identify and quantify substances at the molecular level it is an indispensable tool in various industries, from pharmaceuticals and forensics to environmental monitoring and materials science. However, the power of MS is often hi…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Hadad, Christopher; Lalisse, Remy; Sahraeian, Taghi; Wu, Yiying; Zheng, Jingfeng
- Licensing Officer: Panic, Ana
Co-Axial Contained Electrospray Ionization Platform for Mass Spectrometry
TS-067158 — The Need
Mass spectrometry (MS) is used across a wide range of applications for detection of various chemical analytes such as drug metabolites, pesticides, food adulterants, and natural product extracts. Recent developments have transformed MS into an all-purpose technique for in-situ and real-tim…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Burris, Benjamin "Ben"; Grooms, Alex; Heiss, Derik; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Advanced Mass Spectrometry Hybrid Ionization Technology for Comprehensive Molecular Analysis
TS-066752 —
In today's fast-paced commercial and scientific environments, there is an increasing demand for precise and efficient analytical techniques capable of handling complex mixtures with diverse physicochemical properties. Existing ionization techniques like Electrospray Ionization (ESI) and Atmosp…
- College: College of Arts & Sciences
- Inventors: Badu-Tawiah, Abraham; Damale, Purva; Grooms, Alex; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Specific Pathogen Free Turkey Eggs
TS-065846 — The Need: With the persistent threat of avian diseases, ensuring the health and safety of turkey populations is of utmost importance to the poultry industry. Traditional methods of disease prevention have limitations, necessitating a technology that can reliably produce Specific Pathogen Free (SPF) …
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Saif, Mo
- Licensing Officer: Panic, Ana
SUMO^RIT Tag: Revolutionizing Downstream Gene Translation
TS-065844 — The Need: In modern biotechnology and pharmaceutical industries, precise control over gene expression is paramount. However, conventional translation processes often lead to inefficiencies, resulting in reduced yields and compromised protein function. Meeting the demand for enhanced gene expression …
- College: College of Arts & Sciences
- Inventors: Law, Jamison
- Licensing Officer: Panic, Ana
3D printed Elm leaves to show Elm Zigzag Sawfly (Aproceros leucopoda) larval feeding damage.
TS-065836 — The Need: In today's agricultural landscape, precise identification and monitoring of pest damage are paramount for maintaining crop health and maximizing yields. Traditional methods often fall short in accurately assessing and addressing the impact of pests like the Elm Zigzag Sawfly (Aproceros…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Basnagala, Suranga; Perry, Kayla
- Licensing Officer: Panic, Ana
Precision RNA-PROTACs: Revolutionizing Therapeutic Targeting of Dysregulated Ribonucleoprotein Complexes
TS-065457 — The Need:
In the realm of therapeutic development, there's a pressing need for precise targeting of dysregulated ribonucleoprotein (RNP) complexes to combat various diseases, particularly neurodegenerative disorders like ALS, Alzheimer’s, and Huntington’s diseases. Traditional metho…
- College: College of Arts & Sciences
- Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"; Strong, Rebekah
- Licensing Officer: Panic, Ana
Revolutionizing RNA-Protein Interaction Mapping: Precision Proximity Labeling Technology
TS-065456 — The Need
In modern biological research, there is a pressing demand for technologies that enable precise mapping of RNA-protein interactions within Ribonucleoprotein (RNP) complexes. Traditional methods often lack the capability to pinpoint these interactions at the level of secondary structure moti…
- College: College of Arts & Sciences
- Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"
- Licensing Officer: Panic, Ana
Advancing RNA Detection with Innovative Peptide-Based Fluorescent Probes
TS-065455 — The Need: In modern biotechnology and biomedical research, there is an escalating demand for efficient tools that can accurately detect and analyze specific RNA sequences. The ability to precisely target and identify RNA molecules, particularly U-rich sequences, is crucial for various applications s…
- College: College of Arts & Sciences
- Inventors: Bong, Dennis; DeSantis, Christopher; Gopalan, Venkat; Liang, Yufeng; Mao, Jie; Marathe, Ila; Miao, Shiqin "Shiqin"
- Licensing Officer: Panic, Ana
Ultra Sheer Technology (UST): Revolutionizing Protein Blending for Superior Nutrition and Taste
TS-065233 — The Need: The food industry grapples with meeting escalating consumer demands for health-centric, eco-friendly, and economically viable protein-based diets. Despite the surge in popularity of plant-based milk products, consumer reluctance persists due to lackluster flavors and compromised taste. Add…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Balasubramaniam, V M "Bala"; Janahar, Jerish Joyner; Jimenez-Flores, Rafael
- Licensing Officer: Panic, Ana
Revolutionizing Hydrogen Production and CO2 Capture for a Sustainable Future
TS-065143 — The Need:
In the face of pressing environmental concerns and the imperative for sustainable energy solutions, there arises a critical commercial need for systems and methods that can efficiently produce hydrogen (H2) while simultaneously capturing and converting carbon dioxide (CO2) emissions. Trad…
- College: College of Arts & Sciences
- Inventors: Baker, Lawrence "Robert"
- Licensing Officer: Panic, Ana
Sustainable and Efficient Hydrofunctionalization Catalysts
TS-064828 — The Need:
Efficient and selective hydrofunctionalization of alkenes via catalytic hydroboration, hydrogenation, or hydrosilylation address a critical demand in various chemical sectors. Particularly, in the petrochemical, pharmaceutical, agrochemical, and food industries these reactions play a piv…
- College: College of Arts & Sciences
- Inventors: Thomas, Christine; Fitzsimmons, Matthew
- Licensing Officer: Panic, Ana
Wearable Sensors for Touch-Based Collaboration and Digital Gaming
TS-064825 — he Need
In today's fast-paced and interconnected world, seamless collaboration among individuals is crucial for driving productivity and innovation. Traditional methods of interaction often fall short in capturing the nuances of human collaboration, leading to inefficiencies and misunderstandin…
- College: College of Engineering (COE)
- Inventors: Kiourti, Asimina; King, Cameron; Swearingen, EunKyoung "Kyoung"; Swearingen, Scott; Thrane, Susan; Williamson, Ian
- Licensing Officer: Panic, Ana
Revolutionizing Pharmaceutical Synthesis: Advancements in Metal-Catalyzed Coupling Technology
TS-064824 — The Need
In the pharmaceutical industry, the synthesis of complex organic substrates is crucial for the development of life-saving medications. However, traditional metal-catalyzed coupling reactions often face significant challenges when applied to these complex substrates, leading to high failure…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Dinh, Long; Hamby, Taylor; Starbuck, Hunter
- Licensing Officer: Panic, Ana
Speech Corpus of Regional Dialect
TS-064586 — Speech corpus of regional dialect variation in American English documenting changing pronunciation patterns across several generations of speakers ranging in age from 8 to 101 years old.
The Need
The speech corpus can be used for research on variation and change in spoken language, for the deve…
- College: College of Arts & Sciences
- Inventors: Jacewicz, Ewa; Fox, Robert
- Licensing Officer: Panic, Ana
Magnetic Nanoparticles for Cancer Cell Classification
TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year.
The Need
Developing drugs for cance…
- College: College of Arts & Sciences
- Inventors: Schultz, Zachary; Rist, David; Skardal, Aleksander; Venere, Monica
- Licensing Officer: Panic, Ana
Electrocatalytic grafting and modification of polyvinylchlorides and chloroparaffins
TS-064268 —
Polyvinylchloride (PVC) is a widely used plastic, but its inherent limitations—brittleness, thermal instability, and poor shear strength—pose significant challenges for diverse applications, from medical packaging to construction. Conventional PVC modification relies on high loadings o…
- College: College of Arts & Sciences
- Inventors: Sevov, Christo; Truesdell, Blaise
- Licensing Officer: Panic, Ana
A nitrogenase-like enzyme system that catalyzes methionine, ethylene, and methane biogenesis
TS-064265 —
In industrial settings, the demand for safe and efficient methods of producing ethylene, ethane, and methane is paramount. Existing ethylene production processes often involve oxygen-dependent enzymes, resulting in a flammable ethylene-oxygen gas mixture. Moreover, methane and ethane, when mixed w…
- College: College of Arts & Sciences
- Inventors: North, Justin; Murali, Srividya; Tabita, Fred (Bob) "Bob"; Young, Sarah
- Licensing Officer: Panic, Ana
Utilizing WT-IV-012 to improve immune checkpoint therapy in cancer treatment
TS-064262 — The Need
Addressing the limitations of current melanoma therapies, there exists a critical need for innovative approaches that enhance the effectiveness of immune checkpoint therapeutics. Despite advancements in immunotherapy, a significant percentage of melanoma patients do not achieve complete re…
- College: College of Arts & Sciences
- Inventors: Burd, Craig; Aguilar-Valenzuela, Renan; Burd, Christin
- Licensing Officer: Panic, Ana
How Are You Feeling Today? Organizational Mental Health Indicator and Real-Time Help Application
TS-064244 — The Need: Organizations, particularly college campuses, are facing a growing challenge in addressing student mental health issues. The rising prevalence of severe psychological problems, anxiety disorders, and depression among students necessitates a proactive and effective solution. The existing ga…
- College: College of Engineering (COE)
- Inventors: Ezell, Jonathan; Kaufman, Michael
- Licensing Officer: Panic, Ana
The Six Feelings Framework for Autism Planning and Design Standards
TS-064243 — The Need:
In the realm of urban planning and design, a critical need has emerged to address the unique requirements of adults with autism. The Six Feelings Framework responds to the imperative of creating inclusive public spaces where individuals on the autism spectrum can not only coexist but also…
- College: College of Engineering (COE)
- Inventors: Ezell, Jonathan; Korniyenko, Galyna "Gala"; Stein, Rick
- Licensing Officer: Panic, Ana
Small molecules that suppress heat/pain perception
TS-064187 — The Need
In the culinary and pharmaceutical realms, the need for a groundbreaking solution to modulate flavor and alleviate sensory perceptions is crucial. Businesses seek innovative ways to enhance consumer experiences by addressing pungency in foods and alleviating burn or pain sensations in phar…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Peterson, Devin; Borcherding, Joel
- Licensing Officer: Panic, Ana
A new diagnostic assay for classic galactosemia
TS-064133 — Classic galactosemia is a genetic condition that can lead to life-threatening complications, including feeding problems, failure to thrive, liver damage, bleeding, and sepsis. If a lactose-restricted diet is provided during the first ten days of life, the neonatal symptoms quickly resolve and reduce…
- College: College of Arts & Sciences
- Inventors: Gopalan, Venkat; Bashian, Eleanor; Thirugnanasambantham, Pankajavalli
- Licensing Officer: Panic, Ana
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