# of Displayed Technologies: 7 / 7


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Methods for Making Three Dimensional Microfluidic Bioreactor Array
TS-037642 — Design for a three-dimensional microfluidic bioreactor array; device allows for culturing of a variety of cell types without contamination.
Cell culture in a three-dimensional fluidic-flow microenvironment is critical for long-term cell-based assays. Conducting in vitro research offers an accessible, reproducible, and reliable mode of investigation for therapeutic decisions before work is conducted in vivo. However, because of the com…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Wen, Yuan
  • Licensing Officer: Davis, Stewart

Functionalization of Polymethylmethacrylate (PMMA) Surface by Amination with Polyethyleneimine (PEI) for Applications in Microfluidic Immunoassays, Protein/Enzyme Biochips, and Biocatalysis
TS-037631 — Polymethylmethacrylate (PMMA) is a useful material for development of assays, biochips, and other biological materials. However, PMMA makes for a difficult substrate because of complexities with respect to adhesion. This technology presents two new methods for enhanced protein binding onto PMMA.
Polymethylmethacrylate (PMMA) is a synthetic resin in the acrylic family, often used as a substitute for glass or as a material for biomedical devices. PMMA-based biosensors have low protein binding efficiency and low sensitivity. PMMA is used in a variety of applications like immunoassays, biosen…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Bai, Yunling
  • Licensing Officer: Davis, Stewart

Methods and Processes for Producing Butyrate Esters from Sugars
TS-037568 — A method and process for producing butyrate esters for use as novel biofuels.These products have a similar energy content to biobutanol, but are easier to produce.
Currently, bioethanol is the major biofuel on the market, but recently butanol has gotten attention for its potential as a transportation fuel. It has many characteristics that make it a better fuel source than ethanol: butanol has 25% more Btu per gallon, it's less evaporative/explosive with …
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"
  • Licensing Officer: Davis, Stewart

Metabolic Engineering of Clostridium Tyrobutyricum for Butanol Production
TS-037555 — A new strain of bacteria that can produce butanol at a high titer for transportation fuel.
Butanol is generally used as an industrial solvent but can also be blended with gasoline and used as transportation fuel. Butanol is commonly produced using fossil fuels, but it can also be produced from biomass, referred to as biobutanol. Biobutanol is produced from fermentation of the same feeds…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Yu, Mingrui
  • Licensing Officer: Davis, Stewart

N-Proanol and Propionic Acid Producing Propionibacteria
TS-037515 — New method of producing n-propanol and propionic acid using a metabolically engineered propionibacteria.
Propionibacteria are well-known for their various industrial applications including the manufacturing of Swiss cheese, vitamin B12, and propionic acid. However, not much is known about their genetics, and few studies have been conducted utilizing them for metabolic engineering, mostly in vitamin B…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Ammar, Ehab
  • Licensing Officer: Davis, Stewart

Multichannel Polymer Chips for Rapid Multiplex Enzyme-Linked Immunosorbent Assay
TS-014978 — A more accurate, cost efficient and faster method to one of the most widely used diagnostic tests in the world.
The conventional Enzyme-Linked Immunosorbent Assay, or ELISA, is typically carried out in a 96-well or 384-well microliter plate. The method involves a series of mixing and washing steps, which are not only tedious and laborious, but which also often result in large errors and inconsistent outcome…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Bai, Yunling; Huang, Wei-Cho
  • Licensing Officer: Davis, Stewart

Butanol Production from Renewable Biomass
TS-014747 — A genetically engineered bacteria pathway directed to selectively generate butanol over competing by-products.
Acetone-Butanol-Ethanol (ABE) Fermentation is one of two methods to produce butanol from biomass feedstocks. Various active enzymes or acids are exposed to a biomass feedstock and subsequently produce primarily acetone, butanol and ethanol. Previous attempts in the industry to use Clostridium stra…
  • College: College of Arts & Sciences
  • Inventors: Yang, Shang-Tian "ST"; Zhao, Jingbo
  • Licensing Officer: Davis, Stewart

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