Naked‑Eye Endotoxin Detection via Ligand‑Modified, Lubricant‑Infused Surfaces
TS-073584 —
Endotoxins from gram‑negative bacteria pose serious risks in pharmaceutical manufacturing, medical devices, food, and water systems, even at picogram-per-milliliter levels. Current standard methods, such as the LAL assay, require specialized reagents, laboratory infrastructure, and raise cost, s…
- College: College of Engineering (COE)
- Inventors: Wang, Xiaoguang "William"; Xu, Yang
- Licensing Officer: Randhawa, Davinder
Thermotropic liquid crystal-based sensors for naked-eye detection of SARS-CoV-2 with ultrahigh sensitivity and selectivity
TS-063069 —
In the wake of the global pandemic caused by SARS-CoV-2, the need for rapid, accurate, and efficient diagnostic methods for respiratory viral infections has become more critical than ever. Traditional diagnostic methods, while reliable, are often time-consuming, labor-intensive, and lack the neces…
- College: College of Engineering (COE)
- Inventors: Wang, Xiaoguang "William"; Qin, Rongjun; Rather, Adil; Xu, Yang
- Licensing Officer: Randhawa, Davinder
Selective Estrogen Receptor Beta Agonists
TS-062681 — According to the American Cancer Society, breast cancer is the most common cancer for women in the US, except for skin cancer. It comprised about 30% of all new female cancers each year. While breast cancer death rates have decreased over the last several decades, it remains the second leading cause…
- College: OSU Wexner Medical Center
- Inventors: Bennett, Chad; Wang, Dasheng
- Licensing Officer: Taysavang, Panya
Selective Estrogen Receptor Beta Agonists
TS-062680 — According to the American Cancer Society, breast cancer is the most common cancer for women in the US, except for skin cancer. It comprised about 30% of all new female cancers each year. While breast cancer death rates have decreased over the last several decades, it remains the second leading cause…
- College: College of Pharmacy
- Inventors: Bennett, Chad; Wang, Dasheng
- Licensing Officer: Taysavang, Panya
Novel Live Attenuated Vaccines for Pneumoviruses
TS-037753 — A method to create vaccines for pneumoviruses, using recombinant viruses.
The Need
Pneumoviruses consist of pathogens that target the upper respiratory tract within their specific hosts. These include many important human and animal pathogens, such as human respiratory syncytial virus (hRSV), hMPV, bovine RSV, pneumonia virus of mice (PVM), and avian metapneumovirus (aMP…
- College: College of Veterinary Medicine
- Inventors: Li, Jianrong; Cai, Hui; Peeples, Mark; Wang, Rongzhang
- Licensing Officer: Willson, Christopher
Biomimetic Nanoplatform to Deliver Anti-Restenotic Therapeutics
TS-036654 — A stent-free delivery platform for reducing arterial plaques.
Cardiovascular disease is the leading cause of death in the United States, resulting in more than 600,000 deaths and a significant contributor to overall healthcare costs. Over 28 million Americans are diagnosed with heart disease and contribute more than $30 billion in healthcare-related expenses. …
- College: College of Medicine (COM)
- Inventors: Kent, K. Craig; Chen, Guojun; Gong, Shaoqin; Guo, Lianwang; Urabe, Go; Wang, Bowen
- Licensing Officer: Bhatti, Hamid
Glucose Transporter Inhibitors (GLUT1 Inhibitors)
TS-014734 — A potential cancer treatment that suppresses the ability for cancer cells to intake glucose, thereby hampering cancer cell production.
A fundamental property of neoplastic cells is the shift in cellular metabolism from oxidative phosphorylation to aerobic glycolysis. This glycolytic shift, called the Warburg effect, enables cancer cells to adapt to low-oxygen microenvironments, to generate biosynthetic building blocks for cell pr…
- College: College of Pharmacy
- Inventors: Chen, Ching-Shih; Kulp, Samuel; Wang, Dasheng
- Licensing Officer: Taysavang, Panya