Available Technologies
# of Displayed Technologies: 4 / 4
Applied Category Filter (Click To Remove): Immunology, Autoimmune, Inflammation, Arthritis, Allergies
Novel Natural Product Derivatives Treating Chronic Metabolic and Inflammatory Diseases
TS-075260 — Problem
Type 2 diabetes and related metabolic disorders affect hundreds of millions of patients and are frequently accompanied by chronic inflammation, which accelerates disease progression and complications. Existing antidiabetic therapies often fail to adequately address inflammatory pathways and…
- College: College of Pharmacy
- Inventors: Carcache de Blanco, Esperanza; Anaya Eugenio, Gerardo David; Eggers, Nicole
- Licensing Officer: He, Panqing
Fibroblast-specific LNPs delivering A20 mRNA to treat idiopathic pulmonary fibrosis (IPF)
TS-075175 — Problem
Idiopathic pulmonary fibrosis (IPF) is a chronic disease where activated fibroblasts mediate the abnormal accumulation of extracellular matrix (ECM) in the lung interstitial space, leading to progressive impairment of pulmonary function. Current IPF therapies are associated with significant…
- College: College of Pharmacy
- Inventors: Dong, Yizhou; Kang, Diana; Wang, Chang; Yan, Jingyue
- Licensing Officer: He, Panqing
Novel Natural Product Derivatives Targeting Chronic Diseases
TS-050220 — Novel natural products and derivatives thereof that exhibit potent in vitro and in vivo activity
The Need
Metabolic disorders such as type 2 diabetes are a major health concern that have impacted hundreds of millions of adults worldwide. Current pharmaceutical therapies for type 2 diabetes have been associated with adverse reactions including weight gain and increased risk of infection, liver …
- College: College of Pharmacy
- Inventors: Carcache de Blanco, Esperanza; Anaya Eugenio, Gerardo David; Eggers, Nicole
- Licensing Officer: He, Panqing
Estrogen Receptor Beta Agonist Compounds
TS-015086 — Estrogen Receptor Beta Agonists for the treatment of breast, colon, and prostate cancers as well as inflammatory diseases.
There is a large emphasis on the need for novel and more effective cancer therapeutics, since there were nearly 600,000 cancer deaths in the United States in 2016 alone. One method for therapy of prostate, breast, and colon cancer that has been gaining traction is the targeting of estrogen recepto…
- College: College of Pharmacy
- Inventors: Tjarks, Werner; Bartunek, Petr; Sedlak, David
- Licensing Officer: Taysavang, Panya
