TS-075184 — Problem Synthetic lethality (SL) is defined as a gene combination effect (GCE) of two genes where loss-of-function of both genes, rather than one, causes cell death. While carrying strong therapeutic potential in the treatment of cancer, SL interactions are context specific and sparse, thereby limi…

TS-075183 — Problem Current eligibility biomarkers for Immune checkpoint inhibitors (ICIs) poorly predict patient’s response. Drug clearance, both at baseline and over time, is a stronger predictor of ICI effectiveness, however the current non-linear mixed effects modeling (NLME) approach for estimating …

TS-075168 — Problem Metastasis is the primary driver of cancer-related deaths, yet accurately predicting its onset is a major clinical challenge. Current diagnostic tools often fail to detect occult metastatic cells and metastatic precursor cells, resulting in either overdiagnosis, with unnecessary treatments,…

TS-039267 — A non-invasive and automated tumor budding image analysis system for colorectal cancer. This program can detect tumor buds in traditional H&E stained sections without the need for manual assessment.