Fibroblast-specific LNPs delivering A20 mRNA to treat idiopathic pulmonary fibrosis (IPF)
TS-075175 — Problem
Idiopathic pulmonary fibrosis (IPF) is a chronic disease where activated fibroblasts mediate the abnormal accumulation of extracellular matrix (ECM) in the lung interstitial space, leading to progressive impairment of pulmonary function. Current IPF therapies are associated with significant…
- College: College
of
Pharmacy
- Inventors: Dong, Yizhou; Kang, Diana; Wang, Chang; Yan, Jingyue
- Licensing Officer: He, Panqing