Available Technologies

# of Displayed Technologies: 2 / 2

Applied Category Filter (Click To Remove): Life & Health Sciences

Categories

OSU-ERβ-012 suppresses the inflammatory response in Systemic Lupus Erythematosus

TS-075247 — PROBLEM Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple organ damage, affecting women at a 9:1 rate as compared to men. The etiology of SLE is complex and incompletely understood; however, the susceptibility of women during the years in which estrogen levels ar…

College: College of Medicine (COM)
Inventors: Jarjour, Wael
Licensing Officer: He, Panqing

LNA Inhibitor Cocktail Therapy for Lupus

TS-037260 — A cocktail of locked nucleic acids inhibits the inflammatory response in a humanized murine model of lupus.

Systemic lupus erythematosus (SLE) is an orphan disease affecting approximately 5 in every 10,000 individuals. Despite its rare prevalence, this lifelong autoimmune disease has few effective targeted therapies. Current treatments are palliative using anti-inflammatory drugs or broad spectrum immun…

College: College of Medicine (COM)
Inventors: Jarjour, Wael; Valiente, Giancarlo; Young, Nicholas
Licensing Officer: He, Panqing