Available Technologies
# of Displayed Technologies: 4 / 4
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A new modular format for bispecific antibody fragments
TS-068425 — Functionalization of scFvs with cyclic peptide linkers
The Need
The high specificity of antibodies has been utilized to develop numerous technologies, tools and therapeutics, like ADCs and radiopharmaceuticals. Engineered antibody fragments like single-chain variable fragments (scFvs) are starting to see their way into the clinic in BiTEs and CAR T. Sc…
- College: College of Arts & Sciences
- Inventors: Magliery, Thomas; Do, Jamie; Han, Jeong Min "Mina"; Zhu, Ian
- Licensing Officer: Panic, Ana
Addressing the Challenges in Cancer Imaging
TS-062545 — The Need: Addressing the Challenges in Cancer Imaging
Cancer continues to be a major cause of global mortality, with over 10% of all deaths attributed to this devastating disease. Despite significant advancements in cancer research, there remains a critical need to enhance current techniques for pr…
- College: College of Arts & Sciences
- Inventors: Magliery, Thomas; Long, Nicholas; Sullivan, Brandon
- Licensing Officer: Panic, Ana
Addressing the Challenges in Cancer Imaging
TS-062544 — The Need: Addressing the Challenges in Cancer Imaging
Cancer continues to be a major cause of global mortality, with over 10% of all deaths attributed to this devastating disease. Despite significant advancements in cancer research, there remains a critical need to enhance current techniques for pr…
- College: College of Arts & Sciences
- Inventors: Magliery, Thomas; Allen, Heather; Alten, Edward; Hitchcock, Charles; Long, Nicholas; Martin, Edward; Sullivan, Brandon
- Licensing Officer: Panic, Ana
Immunomodulating agents engineered from Notch receptor ligand extracellular domains
TS-036760 — Immunomodulating agents have been engineered from Notch receptor ligand extracelluar domains. These are useful for stimulating the immune system.
The Notch signaling pathway is important in immune cell differentiation and maturation. As a result, it has been shown that Notch receptor signaling can promote or suppress adaptive immune responses depending on the particular ligands and receptors involved. A set of native protein-inspired biolog…
- College: College of Arts & Sciences
- Inventors: Magliery, Thomas; Carbone, David; Dikov, Mikhail; Long, Nicholas; Sullivan, Brandon; Tchekneva, Elena
- Licensing Officer: Panic, Ana
