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Bidirectional modulation of liver sinusoidal clearance system
TS-075188 — Problem The liver sinusoidal clearance system (LSCS) is responsible for eliminating the majority of circulating macromolecular waste, inflammatory mediators, toxins, and therapeutic agents. Excessive hepatic clearance limits the efficacy of therapies, including chemotherapies and vaccines. In contr…
  • College: College of Education and Human Ecology
  • Inventors: Ziouzenkova, Ouliana; Parquette, Jonathan
  • Licensing Officer: Bhatti, Hamid

Smart Blueberry Extract: The Modern Natural Health Solution for Inflammation Relief and Wellness
TS-071830 — Unlocking plant-powered solutions to deliver effective inflammation relief and enhance disease outcomes.
Overview Chronic inflammation driven by elevated interleukin-11 (IL-11) is a critical underlying cause of tissue scarring and cancer, worsening the disease outcomes over time. Current anti-inflammatory options fall short, offering limited control over IL-11 and failing to stop its persistent buildu…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Giusti, M. Monica; Prasher, Harmeen; Sellers, Patrick; Ziouzenkova, Ouliana
  • Licensing Officer: Panic, Ana

Novel peptides for the treatment of type 1 and 2 diabetes and their neurological complications
TS-037747 — A novel peptide therapeutic AAC2 comprising amino acids with a coumarin-modified side chain that improves glucose control and reduces neurological decline and anxiety through activation of the insulin-insensitive glucose transporter 1 (GLUT1).
A national study done in 2016 on US adults with diabetes estimated that 0.5% of the population was diagnosed with type 1 diabetes (T1D) (~1.6 million) and 8.5% was diagnosed with type 2 diabetes (T2D) (~27 million). Globally there are ~415 million adults living with diabetes in 2015, with a projec…
  • College: College of Education and Human Ecology
  • Inventors: Ziouzenkova, Ouliana; Parquette, Jonathan
  • Licensing Officer: Bhatti, Hamid

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