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Magnetic Nanoparticles for Cancer Cell Classification
TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year. The Need Developing drugs for cance…
  • College: College of Arts & Sciences
  • Inventors: Schultz, Zachary; Rist, David; Skardal, Aleksander; Venere, Monica
  • Licensing Officer: Panic, Ana

A new diagnostic assay for classic galactosemia
TS-064133 — Classic galactosemia is a genetic condition that can lead to life-threatening complications, including feeding problems, failure to thrive, liver damage, bleeding, and sepsis. If a lactose-restricted diet is provided during the first ten days of life, the neonatal symptoms quickly resolve and reduce…
  • College: College of Arts & Sciences
  • Inventors: Gopalan, Venkat; Bashian, Eleanor; Thirugnanasambantham, Pankajavalli
  • Licensing Officer: Panic, Ana

MicroRNA-Based Methods and Compositions for the Diagnosis, Prognosis and Treatment of Solid Cancers
TS-062318 — The Need Cancer is a significant health problem and a leading cause of death in developed countries. Solid cancers, including prostate, breast, lung, stomach, colon, and pancreatic cancers, pose particularly challenging diagnostic and treatment obstacles. Early detection of these cancers is crucial…
  • College: College of Medicine (COM)
  • Inventors: Croce, Carlo; Calin, George; Volinia, Stefano
  • Licensing Officer: Willson, Christopher

Automated Detection of Tumor Budding in Colorectal Cancer
TS-039267 — A non-invasive and automated tumor budding image analysis system for colorectal cancer. This program can detect tumor buds in traditional H&E stained sections without the need for manual assessment.
Colorectal cancer is the third most commonly diagnosed cancer in the United States. With a survival rate of less than 65%, early detection and treatment are key factors in survival. Tumor budding, associated with higher tumor stage, lymph node metastasis, and decreased disease-free survival, has e…
  • College: College of Medicine (COM)
  • Inventors: Gurcan, Metin; Ahmad Fauzi, Mohammad Faizal; Chen, Wei "Wei"; Frankel, Wendy
  • Licensing Officer: Hampton, Andrew

At-Home Digital Platform for Scoring Skin Disease
TS-038429 — An automated image analysis system for the recognition and quantification of skin disease
Acne and rosacea are skin diseases that affect around 85% of individuals, the former being the most common skin condition afflicting up to 50 million people. There is no gold standard for evaluation of these skin diseases, and their treatment efficacy is generally determined according to a poorly …
  • College: College of Medicine (COM)
  • Inventors: Kaffenberger, Benjamin; Gurcan, Metin
  • Licensing Officer: Hampton, Andrew

miRNA-based Predictive Model for Biochemical Failure Following Post-Prostatectomy Salvage Radiation Therapy
TS-037521 — A method to use MiRNA to predict the likelihood of biochemical failure after radiation surgery.
The Need Prostate cancer is one of the most common cancers worldwide, but current treatments can sometimes lead to complications. For example, radical prostatectomy is widely used for men in the early stages of prostate cancer, but long-term data shows that 30-40% of these patients experience bioch…
  • College: College of Medicine (COM)
  • Inventors: Chakravarti, Arnab; Bell, Erica
  • Licensing Officer: Schworer, Adam

Rapid Diagnosis of a Disease Condition using Infrared Spectroscopy
TS-014897 — This invention aids rapid diagnosis of a disease condition through the use of infrared spectral data and multivariate disease classification models.
The Need: Functional syndromes, such as chronic fatigue syndrome, fibromyalgia, interstitial cystitis (IC), and irritable bowel syndrome, pose significant challenges for healthcare providers due to their elusive pathophysiological mechanisms and overlapping symptoms with other conditions. The lack o…
  • College: College of Veterinary Medicine
  • Inventors: Buffington, Charles "Tony"; Rodriguez-Saona, Luis; Rubio Diaz, Daniel; Stella, Judith
  • Licensing Officer: Willson, Christopher

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