Available Technologies
# of Displayed Technologies: 10 / 16
Applied Category Filter (Click To Remove): Drug Delivery
Cell-Penetrating Peptides: Revolutionizing Intracellular Delivery
TS-066751 —
In the rapidly evolving field of biotechnology and pharmaceuticals, there is a critical need for efficient delivery mechanisms to transport therapeutic agents directly into cells. Traditional methods face challenges with membrane impermeability and degradation of therapeutic compounds, limiting th…
- College: College of Arts & Sciences
- Inventors: Pei, Dehua
- Licensing Officer: Dahlman, Jason "Jay"
Novel Therapeutic Approach to Treating Painful Musculoskeletal Disorders
TS-065684 — Non-viral gene therapy for minimally invasively treating painful musculoskeletal disorders
Painful musculoskeletal disorders like intervertebral disc (IVD) degeneration associated with chronic low back pain (DBP) present a significant socio-economic burden worldwide.
The Need
Current treatments for painful musculoskeletal disorders offer only temporary relief or invasive surgical proce…
- College: College of Engineering (COE)
- Inventors: Walter, Devina; Gallego Perez, Daniel; Higuita Castro, Natalia; Khan, Safdar; Tang, Shirley "Shirley Nina"; Walter, Benjamin
- Licensing Officer: Willson, Christopher
Novel Extracellular Vesicles Loaded with Anti-Inflammatory Agents
TS-065154 — , 2018-345 Revolutionary treatment for ARDS using novel extracellular vesicles loaded with Anti-Inflammatory Agents.
The Need
Acute Respiratory Distress Syndrome (ARDS) remains a significant healthcare challenge with high mortality rates and long-term morbidity. Despite advancements in supportive care, there’s an urgent need for pharmacologic treatments targeting the molecular mechanisms driving ARDS pathog…
- College: College of Medicine (COM)
- Inventors: Karpurapu, Manjula; Christman, John; Parinandi, Narasimham
- Licensing Officer: Willson, Christopher
Advanced AAV Gene Therapy Characterization Technique
TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …
- College: College of Arts & Sciences
- Inventors: Wysocki, Vicki; Cleary, Sean; Du, Chen
- Licensing Officer: Dahlman, Jason "Jay"
Localized Cylindrical Drug Delivery to Prevent Vascular Restenosis
TS-062216 — The Need: Addressing Vascular Restenosis with Extended Drug Delivery
Vascular restenosis poses a significant medical challenge in the United States, particularly in cases of coronary artery disease treated with bypass grafting. The current methods involve using drug-loaded polymer formulations to d…
- College: College of Engineering (COE)
- Inventors: Lannutti, John
- Licensing Officer: Dahlman, Jason "Jay"
Ehrlichial Ligand for Host Cell Invasion- Drug Delivery Approach
TS-062208 — The Need: Tick-borne zoonosis caused by Ehrlichia chaffeensis is a growing concern, leading to a febrile disease that can be fatal, especially in immunocompromised and elderly individuals. Early diagnosis and appropriate treatment with doxycycline are crucial to prevent severe complications. However…
- College: College of Veterinary Medicine
- Inventors: Rikihisa, Yasuko
- Licensing Officer: Willson, Christopher
Drug Delivery System for the Treatment of Neurological Diseases
TS-054464 — Novel drug delivery system that enables efficient transfer of FDA-approved drugs for the treatment of neurological injuries.
Traumatic brain and spinal cord injury cause devastating neurological deficits and long-term disability due to detrimental structural and functional alteration in neuronal circuits. Treatment of brain injury and neurological disorders has traditionally been challenging due to the inability to deli…
- College: College of Engineering (COE)
- Inventors: Lannutti, John; Fan, Fan; Tedeschi, Andrea
- Licensing Officer: Willson, Christopher
Stealth liposomes with greater stability for improved drug delivery
TS-048888 —
Liposome drug delivery systems play a significant role in the formulation of new therapies. These liposome-encapsulated drugs are used to treat a wide range of diseases such as cancer, influenza, and hepatitis. While endogenous liposomes are recognized by the mononuclear phagocyte system and clear…
- College: College of Arts & Sciences
- Inventors: Bong, Dennis
- Licensing Officer: Panic, Ana
Multi-Functional Drug Delivery Nanodevice for Precision Medicine
TS-041485 — A functionalized DNA nanostructure made through a scaffolded DNA origami molecular self-assembly process to deliver clinically significant concentrations of therapeutics.
This novel therapeutic approach leverages structural nanotechnology to create a DNA nanostructure that acts as a customizable delivery vehicle for therapeutic molecules. The technology allows for a highly tunable and customizable multi-functional drug delivery platform that incorporates interchang…
- College: College of Engineering (COE)
- Inventors: Castro, Carlos; Byrd, John; Halley, Patrick; Lucas, Christopher
- Licensing Officer: He, Panqing
Perivascular Drug Delivery Nanoplatform for Preventing Restenosis After Open Surgery
TS-039004 — Pericelle: a nanoparticle based perivascular drug delivery system to prevent stenosis and failure in vascular reconstruction surgeries.
Imaging and re-intervention procedures, necessary to maintain open blood vessels following vascular reconstruction surgery, are expensive. For example, the cost of maintenance for an arteriovenous (AV) fistula used in hemodialysis access has been estimated at $15,000/year. In bypass and AV fistula…
- College: College of Medicine (COM)
- Inventors: Kent, K. Craig; Chen, Guojun; Gong, Shaoqin; Guo, Lianwang; Shi, Xudong
- Licensing Officer: Taysavang, Panya
