Available Technologies
# of Displayed Technologies: 10 / 15
Applied Category Filter (Click To Remove): Therapeutics
Novel HIV Targeting Strategy for Next‑Generation Antivirals
TS-074218 — This HIV-focused technology introduces a novel strategy for engaging conserved viral biology that is not directly addressed by existing antiretroviral classes. By expanding the range of actionable HIV mechanisms, the approach creates new opportunities for therapeutic discovery, combination strategies, and next‑generation intervention concepts. The technology is designed to complement current HIV treatment paradigms while supporting diversification of long‑term antiviral pipelines.
Technology Overview
This HIV-focused technology introduces a novel strategy for engaging conserved viral biology that is not directly addressed by existing antiretroviral classes. By expanding the range of actionable HIV mechanisms, the approach creates new opportunities for therapeutic discove…
- College: College of Arts and Sciences (ASC)
- Inventors: Musier-Forsyth, Karin; Kelley, Elise; Nielsen, Andrew
- Licensing Officer: Panic, Ana
Cyclic Cell-Penetrating Peptides: Revolutionizing Intracellular Delivery
TS-073895 — The Need
In the rapidly evolving field of biotechnology and pharmaceuticals, there is a critical need for efficient delivery mechanisms to transport therapeutic agents directly into cells. Cell-penetrating peptides (CPPs) initially were considered a potential solution. Short sequences of amino acid…
- College: College of Arts and Sciences (ASC)
- Inventors: Pei, Dehua
- Licensing Officer: Dahlman, Jason "Jay"
Breakthrough In Delivery: Expanding Access to Intracellular Targets for Next-Generation Therapies
TS-072004 — Empower your pipeline with a versatile platform for efficient, customizable biomolecule transport.
Overview
Intracellular delivery remains a persistent challenge in drug delivery, gene editing, and biotechnology. Pharmaceutical and biotech companies lose valuable opportunities when promising drugs and biologics cannot reach their intended targets inside cells, limiting product effectiveness and m…
- College: College of Arts and Sciences (ASC)
- Inventors: Bong, Dennis
- Licensing Officer: Panic, Ana
A new modular format for bispecific antibody fragments
TS-068425 — Functionalization of scFvs with cyclic peptide linkers
The Need
The high specificity of antibodies has been utilized to develop numerous technologies, tools and therapeutics, like ADCs and radiopharmaceuticals. Engineered antibody fragments like single-chain variable fragments (scFvs) are starting to see their way into the clinic in BiTEs and CAR T. Sc…
- College: College of Arts and Sciences (ASC)
- Inventors: Magliery, Thomas; Do, Jamie; Han, Jeong Min "Mina"; Zhu, Ian
- Licensing Officer: Panic, Ana
Cyclic Cell-Penetrating Peptides: Revolutionizing Intracellular Delivery
TS-066751 — The Need
In the rapidly evolving field of biotechnology and pharmaceuticals, there is a critical need for efficient delivery mechanisms to transport therapeutic agents directly into cells. Cell-penetrating peptides (CPPs) initially were considered a potential solution. Short sequences of amino acid…
- College: College of Arts and Sciences (ASC)
- Inventors: Pei, Dehua
- Licensing Officer: Dahlman, Jason "Jay"
Precision RNA-PROTACs: Revolutionizing Therapeutic Targeting of Dysregulated Ribonucleoprotein Complexes
TS-065457 — The Need:
In the realm of therapeutic development, there's a pressing need for precise targeting of dysregulated ribonucleoprotein (RNP) complexes to combat various diseases, particularly neurodegenerative disorders like ALS, Alzheimer’s, and Huntington’s diseases. Traditional metho…
- College: College of Arts and Sciences (ASC)
- Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"; Strong, Rebekah
- Licensing Officer: Panic, Ana
Addressing the Challenges in Cancer Imaging
TS-062545 — The Need: Addressing the Challenges in Cancer Imaging
Cancer continues to be a major cause of global mortality, with over 10% of all deaths attributed to this devastating disease. Despite significant advancements in cancer research, there remains a critical need to enhance current techniques for pr…
- College: College of Arts and Sciences (ASC)
- Inventors: Magliery, Thomas; Long, Nicholas; Sullivan, Brandon
- Licensing Officer: Panic, Ana
Addressing the Challenges in Cancer Imaging
TS-062544 — The Need: Addressing the Challenges in Cancer Imaging
Cancer continues to be a major cause of global mortality, with over 10% of all deaths attributed to this devastating disease. Despite significant advancements in cancer research, there remains a critical need to enhance current techniques for pr…
- College: College of Arts and Sciences (ASC)
- Inventors: Magliery, Thomas; Allen, Heather; Alten, Edward; Hitchcock, Charles; Long, Nicholas; Martin, Edward; Sullivan, Brandon
- Licensing Officer: Panic, Ana
Novel use of novobiocin to potentiate the antimicrobial efficacy of polymyxins
TS-062439 — The Need: Addressing the Growing Threat of Gram-Negative Bacterial Infections
Gram-negative bacterial pathogens, including Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae, are responsible for more than 35% of common hospital-acquired infections. These no…
- College: College of Arts and Sciences (ASC)
- Inventors: Kahne, Daniel; Baidin, Vadim; Mandler, Michael; Ruiz, Natividad
- Licensing Officer: Dahlman, Jason "Jay"
Mini-PCDH15 for treatment of deafness
TS-050433 — A gene therapy solution for Usher Syndrome Type 1F.
Mutations in PCDH15 cause Usher 1F, a recessive syndrome characterized by profound congenital deafness and absence of vestibular function, and progressive blindness beginning in the second decade. Because patients who lack hearing and balance rely on vision for communication and mobility, the late…
- College: College of Arts and Sciences (ASC)
- Inventors: Sotomayor, Marcos
- Licensing Officer: Dahlman, Jason "Jay"
