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Diffusion-Only Microfluidic Platform for Spatiotemporal Cell Signaling Analysis
TS-073289 — Understanding how cells respond to soluble signals under diffusion-limited conditions remains a significant gap in current in vitro models. Most microfluidic systems rely on convective flow, which does not accurately reflect transport in interstitial tissue or solid tumors, where diffusion dominat…
  • College: College of Engineering (COE)
  • Inventors: Fuller, Brendan; Jones, Travis; Song, Jonathan "Jon"
  • Licensing Officer: Ashouripashaki, Mandana

Low-Cost, Multiplexed Microfluidic Force Spectroscopy on-a-Chip
TS-057780 — A novel, low-cost, and massively-parallel force spectroscopy strategy that leverages microfluidic technology to dynamically test strength of molecular binding interactions to enable quick, full characterization of a molecular interaction of interest.
Development of several force spectroscopy strategies have enabled characterization of various types of molecular binding interactions with applications in biophysics, molecular biology and medicine. Despite various efforts to decrease the cost of force spectroscopy, full characterization of a mole…
  • College: College of Engineering (COE)
  • Inventors: Akbari, Ehsan; Castro, Carlos; Shahhosseini, Melika; Song, Jonathan "Jon"
  • Licensing Officer: He, Panqing

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