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Breaking the Cycle of Ehrlichiosis: A Novel RipE-Based Vaccine and Detection Platform
TS-072613 — A novel vaccine and diagnostic platform targeting the conserved Ehrlichia virulence factor RipE offers the first pan-Ehrlichia solution for preventing and detecting tick-borne ehrlichiosis in humans and animals.
Tick-borne ehrlichiosis cases continue to rise globally, yet no licensed human vaccine exists and current diagnostic tools remain limited. Existing approaches struggle due to the pathogen’s antigenic variability, intracellular lifecycle, and lack of classical surface PAMPs, hindering effecti…
- College: College of Veterinary Medicine
- Inventors: Rikihisa, Yasuko
- Licensing Officer: Dahlman, Jason "Jay"
Addressing Tick-Borne Diseases with Advanced Therapeutic Interventions
TS-062227 — he Need:
Tick-borne diseases, especially Human Monocytic Ehrlichiosis (HME), have become a significant public health concern in the United States due to their prevalence, life-threatening nature, and lack of effective treatment options. Current therapies are limited to the broad-spectrum antibiotic…
- College: College of Veterinary Medicine
- Inventors: Rikihisa, Yasuko; Zhang, Wenqing
- Licensing Officer: Dahlman, Jason "Jay"
