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NucNano: Predictive Drug Screening Platform

TS-071946 — Mechanistic drug screening technology to improve preclinical decision-making and reduce late-stage development risk.

Technology Summary NucNano is an emerging drug screening platform from The Ohio State University designed to help pharmaceutical and biotechnology companies identify more promising therapeutic candidates earlier in development. By moving beyond conventional assays that primarily measure bindin…

College: College of Arts and Sciences (ASC)
Inventors: Poirier, Michael; Bonin, Kalven; Bundschuh, Ralf; Castro, Carlos
Licensing Officer: Panic, Ana

Low-Cost, Multiplexed Microfluidic Force Spectroscopy on-a-Chip

TS-057780 — A novel, low-cost, and massively-parallel force spectroscopy strategy that leverages microfluidic technology to dynamically test strength of molecular binding interactions to enable quick, full characterization of a molecular interaction of interest.

Development of several force spectroscopy strategies have enabled characterization of various types of molecular binding interactions with applications in biophysics, molecular biology and medicine. Despite various efforts to decrease the cost of force spectroscopy, full characterization of a mole…

College: College of Engineering (COE)
Inventors: Akbari, Ehsan; Castro, Carlos; Shahhosseini, Melika; Song, Jonathan "Jon"
Licensing Officer: He, Panqing