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mCherry Fluorescence-Producing Ehrlichia chaffeensis: Revolutionizing Bacterial Detection
TS-065847 — The Need: In today's world, rapid and accurate detection of bacterial pathogens is crucial for safeguarding public health and animal well-being. With the emergence of diseases transmitted by ticks and the increasing importance of understanding vector-borne infections, there's a pressing need…
  • College: College of Veterinary Medicine
  • Inventors: Rikihisa, Yasuko; Lin, Mingqun "Mingqun"
  • Licensing Officer: Dahlman, Jason "Jay"

SCTaware: Empowering Health Equity through Virtual Sickle Cell Trait Education
TS-062440 — The Need: Sickle Cell Trait (SCT) affects a significant portion of the population, posing a pressing public health concern. Lack of awareness and limited access to understandable information about SCT's reproductive implications contribute to health disparities among affected individuals. In-per…
  • College: College of Arts & Sciences
  • Inventors: Chan, Peter; McCorkle, Benson; Shen, Yvette
  • Licensing Officer: Panic, Ana

A novel VSV-based vaccine platform for Zika virus
TS-062261 — The Need: Addressing the Zika Virus Outbreak The Zika virus outbreak, which started in South America and quickly became a global public health issue, has led to severe neurological disorders, birth defects, and other health complications in affected populations. Despite efforts to combat the virus,…
  • College: College of Medicine (COM)
  • Inventors: Peeples, Mark; Li, Jianrong
  • Licensing Officer: Dahlman, Jason "Jay"

Live Attenuated Mumps Virus-Based SARS-CoV-2 Vaccines for Infants and Children
TS-062231 — The Need: Addressing the Urgent Need for a Safe and Effective SARS-CoV-2 Vaccine for Infants and Children The ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought about significant economic, emotional, and public health challenges worldwide. The pressing dema…
  • College: College of Veterinary Medicine
  • Inventors: Li, Jianrong; Boyaka, Prosper; Lu, Mijia; Zhang, Yuexiu
  • Licensing Officer: Dahlman, Jason "Jay"

Addressing Tick-Borne Diseases with Advanced Therapeutic Interventions
TS-062227 — he Need: Tick-borne diseases, especially Human Monocytic Ehrlichiosis (HME), have become a significant public health concern in the United States due to their prevalence, life-threatening nature, and lack of effective treatment options. Current therapies are limited to the broad-spectrum antibiotic…
  • College: College of Veterinary Medicine
  • Inventors: Rikihisa, Yasuko; Zhang, Wenqing
  • Licensing Officer: Dahlman, Jason "Jay"

A liposomal subunit flu vaccine formulation
TS-062211 — The Need: Addressing the Limitations of Current Flu Vaccines Influenza epidemics and pandemics present significant challenges to public health and global economies. Existing flu vaccines are strain-specific, providing limited cross-protective immunity and often lack long-term effectiveness. Additio…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Gourapura, Renukaradhya; Carson, Kennith; Cheng, Xingguo; Dhakal, Santosh; Lee, Chang Won; McDonough, Joseph
  • Licensing Officer: Dahlman, Jason "Jay"

Water treatment to eliminate cyanobacteria and other toxins by unmanned surface vehicles (USVs)
TS-058408 — Freshwater resources around the world are under stress due to naturally occurring events and human impacts, causing an increase in cyanobacteria blooms. These cyanobacteria release harmful toxins, known as cyanotoxins. The proposed USV degrades the toxins on-site with UV light, reducing the accumulation of toxins, preventing groundwater contamination, and improving water quality.
Treatment of cyanobacteria and cyanotoxins is necessary before they reach a critical point, or they can contaminate other environments. For example, waste produced by water treatment facilities serves as fertilizer for agricultural land, and if not properly treated, toxic cyanobacteria can grow in…
  • College: College of Public Health
  • Inventors: Lee, Jiyoung; Byrd, Kendall
  • Licensing Officer: Randhawa, Davinder

Antimicrobials to Control Campylobacter
TS-044474 — The Need: Addressing the Growing Threat of Foodborne Illness Foodborne illnesses caused by bacterial pathogens pose a significant public health concern worldwide, leading to millions of illnesses and thousands of deaths each year. Traditional antimicrobial therapies are facing challenges due to the…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Acuna, Ulyana Munoz; Antwi, Janet; Carcache de Blanco, Esperanza; Fuchs, James; Kumar, Anand; Nislow, Corey; Pascall, Melvin
  • Licensing Officer: Dahlman, Jason "Jay"

Live vaccine candidate for Chagas disease
TS-044084 — Trypanosoma cruzi is a protozoan parasite that causes Chagas disease, a PRV-eligible disease that is the leading cause of heart failure in Latin America. Due to migration of infected hosts from endemic regions, Chagas disease is also a growing public health concern in the USA and other migrant des…
  • College: College of Medicine (COM)
  • Inventors: McGwire, Bradford
  • Licensing Officer: He, Panqing

Control of Salmonella in poultry using new generation small molecule growth inhibitors
TS-039567 — Small molecule compounds that can be used to inhibit Salmonella growth for safe and sustainable poultry production.
The Need: Controlling Microbial Growth for Public Health and Safety The increasing incidence of foodborne illnesses caused by bacterial pathogens poses significant public health risks and economic burdens worldwide. Conventional antimicrobial treatments have become less effective, and the developme…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Rajashekara, Gireesh; Deblais, Loic; Kathayat, Dipak; Miller, Sally; Mohamed, Yosra
  • Licensing Officer: Dahlman, Jason "Jay"

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