TS-065859 — FIELD: Revolutionizing Canine Lung Cancer Treatment The Need: Lung cancer in canines poses significant clinical challenges, mirroring the complexities of human lung cancer in non-smokers. With limited standard treatments beyond surgery, there's an urgent demand for advanced methods to assess, c…

TS-065847 — The Need: In today's world, rapid and accurate detection of bacterial pathogens is crucial for safeguarding public health and animal well-being. With the emergence of diseases transmitted by ticks and the increasing importance of understanding vector-borne infections, there's a pressing need…

TS-065843 — The Need Potomac horse fever (PHF) poses a significant threat to equine health, presenting as a severe and often fatal febrile diarrheal disease. Current understanding identifies Neorickettsia risticii as the sole causative agent, associated with digenean trematodes. However, recent research reveal…

TS-065842 — The Need Potomac horse fever (PHF) poses a significant threat to equine health, presenting as a severe and often fatal febrile diarrheal disease. Current understanding identifies Neorickettsia risticii as the sole causative agent, associated with digenean trematodes. However, recent research reveal…

TS-065841 — The Need Potomac horse fever (PHF) poses a significant threat to equine health, presenting as a severe and often fatal febrile diarrheal disease. Current understanding identifies Neorickettsia risticii as the sole causative agent, associated with digenean trematodes. However, recent research reveal…

TS-065394 — The Need: In the dairy industry, combating Salmonella Dublin is crucial due to production losses and its impact on human health. Current detection methods, particularly culture-based techniques, are laborious, time-consuming, and lack sensitivity in environmental samples. As a result, treatment effe…

TS-064192 — The Need: The global impact of the SARS CoV-2 coronavirus has created an urgent need for innovative medical interventions to address the challenges posed by COVID-19. Despite the availability of vaccines, sub-optimal vaccine uptake and concerns about new virus variants necessitate additional medical…

TS-064191 — The emergence of SARS-CoV-2 variants poses a significant challenge to existing COVID-19 vaccines, necessitating the development of a more durable and broadly protective solution. Current vaccines show reduced efficacy over time and struggle against Variants of Concern (VoCs) such as Omicron. Addre…

TS-064189 — The Need The current global landscape demands innovative solutions to address the urgent need for a safe and efficacious SARS-CoV-2 vaccine, particularly for the vulnerable population of infants and children under 12 years old. Existing vaccines face challenges in terms of durability, cost, and sta…

TS-062421 — The Need: Addressing the Global HTLV-1 Epidemic with a Novel Vaccine Human T cell leukemia virus type-1 (HTLV-1) is a significant global health concern, responsible for causing Adult T cell leukemia/lymphoma (ATLL) and human myelopathy/tropical spastic paraparesis (HAM/TSP). With over 10 million pe…

TS-062349 — The Need In the veterinary field, there is a crucial need for accurate and specific diagnostic tests to identify and distinguish between Anaplasma platys (Apl) and other related pathogens like Anaplasma phagocytophilum (Aph). Current diagnostic methods lack specificity, leading to challenges in dif…

TS-062231 — The Need: Addressing the Urgent Need for a Safe and Effective SARS-CoV-2 Vaccine for Infants and Children The ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought about significant economic, emotional, and public health challenges worldwide. The pressing dema…

TS-062227 — he Need: Tick-borne diseases, especially Human Monocytic Ehrlichiosis (HME), have become a significant public health concern in the United States due to their prevalence, life-threatening nature, and lack of effective treatment options. Current therapies are limited to the broad-spectrum antibiotic…

TS-062213 — The Need: Preventing Respiratory Syncytial Virus (RSV) Infection and Disease Respiratory Syncytial Virus (RSV) is a highly prevalent and dangerous pathogen responsible for significant morbidity and mortality, particularly in infants, young children, and immunocompromised individuals. Despite its gl…

TS-062208 — The Need: Tick-borne zoonosis caused by Ehrlichia chaffeensis is a growing concern, leading to a febrile disease that can be fatal, especially in immunocompromised and elderly individuals. Early diagnosis and appropriate treatment with doxycycline are crucial to prevent severe complications. However…

TS-040419 — A method of identifying a canine lymphoid neoplastic disease with no clinical symptoms using plasma DNA.

TS-037753 — A method to create vaccines for pneumoviruses, using recombinant viruses.

TS-037299 — Recombinant vesicular stomatitis virus (rVSV) vaccines to fight against respiratory syncytial virus (RSV) infections.

TS-032198 — A parenteral administration of a naturally occurring chemical used to treat influenza­-induced hypoxemia, lung dysfunction, and acute respiratory distress syndrome (ARDS). This treatment could also be potentially useful in treating ARDS from other causes.

TS-015239 — Enhancing the mucosal (IgA) immune response by transiently blocking a specific cellular subset during vaccination.