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Hybrid Collaborative Filtering Methods for Recommending Search Terms to Clinicians
TS-063237 — Electronic Health Records (EHR) are used in over 88% of all US medical clinics to improve care and streamline data. In addition, they enable sharing of data to multiple providers dealing with the same patient, thereby enhancing efficiency and care. The Need In the last decade, medical practices…
  • College: College of Medicine (COM)
  • Inventors: Ning, Xia; Peng, Bo; Ren, Zhiyun
  • Licensing Officer: Hampton, Andrew

Fast-charging anodes for lithium-ion batteries
TS-063224 — The Need In the rapidly evolving landscape of electric vehicle (EV) technology, there exists a pressing commercial need for rechargeable lithium-ion batteries (LiBs) that can not only deliver high charge capacities and power densities but also address the critical issues of capacity fading and safe…
  • College: College of Engineering (COE)
  • Inventors: Kim, Jung Hyun; Jiao, Xinwei "Jocelyn"; Yap, Jun Wei; Yu, Chanyeop
  • Licensing Officer: Randhawa, Davinder

Substrates for vertical power devices
TS-062951 — The Need In today's fast-paced technological landscape, there is an ever-growing demand for high-performance vertical power devices with enhanced breakdown voltage capabilities, exceeding 20 kV. Meeting this commercial need requires an innovative approach to semiconductor drift layer developmen…
  • College: College of Engineering (COE)
  • Inventors: Zhao, Hongping; Bhuiyan, A F M Anhar Uddin; Meng, Lingyu
  • Licensing Officer: Randhawa, Davinder

Bi-specific T-Cell Engagers as Anti-cancer Therapeutics
TS-062677 — Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths. The most common cancers are breast, lung, colon and rectum and prostate cancers. The Need Current cancer treatments mainly rely on chemotherapy, radiation, surgery and bon…
  • College: College of Medicine (COM)
  • Inventors: Caligiuri, Michael; Chan, Wing; Yu, Jianhua
  • Licensing Officer: Taysavang, Panya

Fluorescent probes for intracellular RNA tracking
TS-062554 — The Need: Intracellular RNA fluorescence labeling is a crucial technique for studying cellular processes and understanding gene expression. However, the conventional MS2 labeling method using protein fusion labels can have drawbacks, such as increased mass, potential steric accessibility issues, and…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng
  • Licensing Officer: Panic, Ana

Addressing the Treatment Gap in Advanced Liposarcoma
TS-062480 — Novel therapeutic compounds to treat advanced liposarcoma.
Patients diagnosed with advanced liposarcoma (LPS) face a significant treatment challenge, as current chemotherapy approaches exhibit low response rates of only 25%, leading to a dismal overall survival at 5 years, ranging between 20% to 34%. The Need Despite extensive efforts, there has been no s…
  • College: College of Medicine (COM)
  • Inventors: Beane, Joal; Goryunova, Marina; Hadad, Christopher; He, Yiran; Zhu, Hua
  • Licensing Officer: Willson, Christopher

Revolutionizing Cancer Research: Unveiling the Dynamics of K-Ras for Targeted Therapies
TS-062433 — The Need: Understanding the intricate functions of the K-Ras protein is crucial in combating various types of human cancer. However, the lack of detailed atomic-level information has hindered progress in this area, leaving significant gaps in our comprehension of its roles in health and disease. Th…
  • College: Enterprise for Research, Innovation and Knowledge (ERIK)
  • Inventors: Bruschweiler, Rafael; Bruschweiler-Li, Lei "Lei"; Hansen, Alexandar "Alex"; Xiang, Xinyao; Yuan, Chunhua
  • Licensing Officer: Dahlman, Jason "Jay"

MRI Transmit Field Estimation in K-space Domain
TS-062329 — The Need: Medical imaging plays a crucial role in diagnosing various diseases, and Magnetic Resonance Imaging (MRI) has emerged as one of the most important imaging modalities due to its safety and effectiveness. Unlike other imaging methods that use ionizing radiation, MRI poses far fewer risks to …
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua; Ding, Yu
  • Licensing Officer: Panic, Ana

Method for Preparing High-Energy Electrodes with Controlled Microstructures for Energy-Storage Devices
TS-061848 — The current manufacturing methods for Lithium-Ion Batteries are limited to around 200 Wh/kg. Power density is a factor of the battery construction and is highly dependent on the electrodes.
The Need Conventional Li-ion batteries consist of electrodes constructed of stacks of 70 µm films. The thin electrodes then require current collectors and separators for assembly, which increase mass without adding charge capacity. The need for these inactive components limits the power densi…
  • College: College of Engineering (COE)
  • Inventors: Kim, Jung Hyun; Rao, Lalith; Sayre, Jay
  • Licensing Officer: Randhawa, Davinder

A Lightweight Low Inductance Power Module with Insulated Baseplates
TS-048588 — A lightweight power module that reduces loop stray inductance while maintaining good electrical insulation and thermal dissipation.
In conventional power module structures, the die is attached to the substrate, usually direct bonding copper (DBC). The ceramic substrate layer provides electrical insulation between the circuit and cooling structure and attaches to a conductive baseplate material (Cu, Al, AlSiC) to dissipate heat…
  • College: College of Engineering (COE)
  • Inventors: Lyu, Xintong; Wang, Jin
  • Licensing Officer: Ashouripashaki, Mandana

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