Available Technologies
# of Displayed Technologies: 2 / 2
Engineered Guide RNA as a Tool for CRISPR/Cpf1 Gene Editing
TS-036754 — This technology aims to optimize the CRISPR-Cpf1 complex by chemically modifying the crRNA nucleotides and engineering crRNA sequences.
CRISPR technology is a new and exciting tool for editing the genomes of live organisms. With CRISPR, researchers have replaced target genes with chosen alternative genes in species ranging from bacteria to live mice. The CRISPR system uses either the Cas9 or Cpf1 protein to bind a given DNA sequen…
- College: College of Pharmacy
- Inventors: Dong, Yizhou; Li, Bin
- Licensing Officer: He, Panqing
Modified Guide RNA for CRISPR/Cpf1 Genome Editing System
TS-032141 — The guide RNA is chemically modified to improve Cpf1 nuclease activity, reduce toxicity, decrease off-target effects, and increase stability.
The Need
CRISPR technology is an exciting tool for editing the genomes of live organisms. With CRISPR, researchers have replaced target genes with chosen alternative genes in species ranging from bacteria to live mice. The CRISPR system uses either the Cas9 or Cpf1 protein to bind a given DNA seque…
- College: College of Pharmacy
- Inventors: Dong, Yizhou; Li, Bin
- Licensing Officer: He, Panqing
