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Quadruplex-Based Technology for Mono-Adapter DNA Library Preparation and Isothermal Clone Generation for Next Generation Sequencing (NGS)
TS-037745 — A technique for the isothermal amplification of DNA libraries for a more efficient and robust sequencing method.
Identification of a particular nucleic acid is desirable in the use of diagnostic and forensic applications. However, often the target nucleic acid sequence may only be a small portion of the DNA or RNA in question so that amplification is needed before sufficient quantities are available for iden…
  • College: College of Arts & Sciences
  • Inventors: Kankia, Besik
  • Licensing Officer: Flammang, Ann Marie

Rapidly reversible DNA-quadruplex-based molecular capture system
TS-015081 — A specific and rapidly reversible system for single molecule capture employing magnesium-dependent DNA quadruplex structures.
Research and medical technology are increasingly dependent on single molecule capture and analysis. The current gold standard for non-covalent immobilization is streptavidin-biotin (STV-B). Although widely used, the biotin component in the interaction is resistant to dissociation, thus requiring h…
  • College: College of Arts & Sciences
  • Inventors: Kankia, Besik
  • Licensing Officer: Flammang, Ann Marie

Real-Time Quadruplex Priming Amplification (QPA) for Nucleic Acid Amplification and Quantification
TS-014824 — An enhanced nucleic acid amplification system that is more efficient and cost-effective than conventional polymerase chain reaction methods.
Identification of a particular nucleic acid is desirable in the use of diagnostic and forensic applications. However, often the target nucleic acid sequence may only be a small portion of the DNA or RNA in question so that it might be difficult to detect the presence of the target sequence using p…
  • College: College of Arts & Sciences
  • Inventors: Kankia, Besik
  • Licensing Officer: Flammang, Ann Marie
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