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Phyllanthusmin and acutissimalignan A compound derivatives for anticancer and immunostimulation
TS-037721 — A group of potential antitumor arylnapthalene lactone derivatives, which may be developed as novel anticancer and immunostimulant agents.
Natural products and semi-synthetic derivatives derived from them have been used for anticancer drugs or drug leads for many years. However, side-effects such as myelosuppression and secondary leukemia have been reported. Furthermore, these natural products can be difficult to use for targeting sp…
  • College: College of Pharmacy
  • Inventors: Kinghorn, Alan "Dr. A. Douglas Kinghorn"; Fuchs, James; Huntsman, Andrew
  • Licensing Officer: He, Panqing

Silvestrol as an Immune Adjuvant for Vaccines
TS-014782 — Silvestrol promotes the prevention and treatment of various cancers as an immune adjuvant.
Molecular changes due to malignant tumors and toxicity of chemotherapeutic regimen suppress the immune system of cancer patients. This immunosuppression also leaves patients vulnerable to opportunistic infections and reactivation of latent viral or mycobacterial infections. Immunostimulation, or a…
  • College: College of Medicine (COM)
  • Inventors: Baiocchi, Robert; Grever, Michael; Kinghorn, Alan "Dr. A. Douglas Kinghorn"; Lucas, David; Patton, John
  • Licensing Officer: He, Panqing

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